PARKINSON_DISEASE

作品数:125被引量:198H指数:7
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相关作者:余舒扬陈滢陈晓春王涛张巧俊更多>>
相关机构:首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>
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NP-6 Rb Fraction Combined with Levodopa Prevent Parkinson Disease by Protecting Neurovascular Unit
《神经药理学报》2018年第4期105-105,共1页CHI Bin-bin LIAN Xiao-yuan 
Object:Parkinson disease(PD)is the second most common progressive neurodegenerative disorder.The available therapies for PD only treat the symptoms of the disease,without neuroprotective and disease-modifying effects....
关键词:PARKINSON disease GINSENOSIDES LEVODOPA NEUROVASCULAR unit NEUROPROTECTION 
Parkinson Kinetic Graph: Are Motor Fluctuations in Parkinson Disease Related with Disease Duration?被引量:1
《Advances in Parkinson's Disease》2018年第1期1-6,共6页Esther Berghuis Barbera Van Harten Mirjam Van Kesteren-Biegstraaten Wijnand Rutgers Nicolaas Verwey 
Introduction: The Parkinson’s KinetiGraph (PKG) is a digital measurement system for motor fluctuations (FS). The aim of this study is to investigate whether FS, measured by the PKG, are associated with disease durati...
关键词:Late Stage PARKINSON DISEASE LEVODOPA DISEASE Duration Fluctuations DYSKINESIA BRADYKINESIA 
Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease被引量:3
《Chinese Medical Journal》2017年第9期1085-1092,共8页Si-Yue Li Ya-Li Wang Wen-Wen Liu Dong-Jun Lyu Fen Wang Cheng-Jie Mao Ya-Ping Yang U-Fang Hu Chun-Feng Liu 
This work was supported by grants from the National Natural Science Foundation of China (No. 91649114),Jiangsu Provincial Special Program of Medical Science (No. BL2014042), the Plans for Graduate Research and Innovation in Colleges and Universities of Jiangsu Province (No. KYZZ15_0334), and Suzhou Clinical Research Center of Neurological Disease (No. Szzx201503). This was also partly supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions and Jiangsu Provincial Medical Key Discipline Project.
Background: Parkinson's disease (PD) patients with long-term levodopa (L-DOPA) treatment are suffering from severe circadian dysfunction. However, it is hard to distinguish that the circadian disturbance in pati...
关键词:Circadian Rhythm LEVODOPA Oxidopamine Parkinson Disease 
Evaluation of cardiovascular risk in patients with Parkinson disease under levodopa treatment被引量:3
《Journal of Geriatric Cardiology》2016年第1期75-80,共6页Zeki Yuksel Gunaydln Fahriye Feriha Ozer Ahmet Karagoz Osman Bektas Mehmet Baran Karatas Ash Vural Adil Bayramoglu Abdullah Celik Mehmet Yaman 
BackgroundLevodopa 是在有 Parkinson 疾病(PD ) 的病人的中间的治疗的不可缺少的选择。因为 L-dopa 治疗被显示增加浆液 homocysteine 层次,为心血管的混乱的一个著名风险因素,有在 L-dopa 治疗下面的 PD 的病人将在为未来的增加的...
关键词:Aortic distensibility Aortic stiffness Cardiovascular risk HOMOCYSTEINE Parkinson disease 
Evaluation on the efficacy and safety of Chinese herbal medication Xifeng Dingchan Pill in treating Parkinson's disease: study protocol of a multicenter, open-label, randomized active-controlled trial被引量:7
《Journal of Integrative Medicine》2013年第4期285-290,共6页Jie Zhang Yun-zhi Ma Xiao-ming Shen 
Specific Research Funding for the Traditional Chinese Medicine Industry of State Administration of Traditional Chinese Medicine (No.200807052)
BACKGROUND: Parkinson's disease (PD) is a complicated disease, commonly diagnosed among the elderly, which leads to degeneration of the central nervous system. It presently lacks an effective therapy for its compl...
关键词:Parkinson disease LEVODOPA drugs  Chinese herbal drug toxicity randomized controlled trial clinical protocols 
Experimental Study on Inhibition of Neuronal Toxical Effect of Levodopa by Ginkgo Biloba Extract on Parkinson Disease in Rats被引量:14
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2003年第2期151-153,共3页曹非 孙圣刚 童萼塘 
This project was supported by a grant from National Natural Sciences Foundation of China(No.30170334).
In order to observe neuronal toxical effect of Levodopa and investigate if using Levodopa together with Ginkgo Bilobar Extract (EGb) would be an workable method to treat Parkinson disease, rat models of Parkinson dise...
关键词:ginkgo biloba extract APOPTOSIS L-dihydroxy-phenylalanine 
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