Object:Parkinson disease(PD)is the second most common progressive neurodegenerative disorder.The available therapies for PD only treat the symptoms of the disease,without neuroprotective and disease-modifying effects....
Introduction: The Parkinson’s KinetiGraph (PKG) is a digital measurement system for motor fluctuations (FS). The aim of this study is to investigate whether FS, measured by the PKG, are associated with disease durati...
This work was supported by grants from the National Natural Science Foundation of China (No. 91649114),Jiangsu Provincial Special Program of Medical Science (No. BL2014042), the Plans for Graduate Research and Innovation in Colleges and Universities of Jiangsu Province (No. KYZZ15_0334), and Suzhou Clinical Research Center of Neurological Disease (No. Szzx201503). This was also partly supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions and Jiangsu Provincial Medical Key Discipline Project.
Background: Parkinson's disease (PD) patients with long-term levodopa (L-DOPA) treatment are suffering from severe circadian dysfunction. However, it is hard to distinguish that the circadian disturbance in pati...
Specific Research Funding for the Traditional Chinese Medicine Industry of State Administration of Traditional Chinese Medicine (No.200807052)
BACKGROUND: Parkinson's disease (PD) is a complicated disease, commonly diagnosed among the elderly, which leads to degeneration of the central nervous system. It presently lacks an effective therapy for its compl...
This project was supported by a grant from National Natural Sciences Foundation of China(No.30170334).
In order to observe neuronal toxical effect of Levodopa and investigate if using Levodopa together with Ginkgo Bilobar Extract (EGb) would be an workable method to treat Parkinson disease, rat models of Parkinson dise...