supported by the Heritage College of Osteopathic Medicine at Ohio University and a John J.Kopchick Fellowship Award to SY.
Aim:Patients with prostate cancer frequently develop osteoblastic bone metastases.Canine models are important because dogs are the only mammal to develop spontaneous prostate cancer with osteoblastic bone metastases s...
supported by the National Cancer Institute grant R01 CA225716(to S.V.S.).
Aim:Leelamine(LLM)inhibits the growth of human prostate cancer cells but the underlying mechanism is not fully understood.The present study was undertaken to determine the effect of LLM on cMyc,which is overexpressed ...
Prostate cancer(PCa)is the leading cause of cancer death in men.With more therapeutic modalities available,the overall survival in PCa has increased significantly in recent years.Patients with relapses after advanced ...
Although prostate epithelium concentrates zinc for the purpose of promoting citrate secretion,it loses its capacity to import zinc while undergoing malignant transformation.This exclusion of zinc may be necessary for ...
Breast and prostate cancer are the leading causes of death in females and males, respectively. Triple negative breast cancer (TNBC) does not express the estrogen receptor, progesterone receptor, or human epidermal gro...
Syndrome of inappropriate antidiuresis (SIAD) is a common paraneoplastic syndrome commonly associated with thoracic malignancies, gastrointestinal cancers and kidney tumors. It is defined as hyponatremia in euvolemic ...
Aim:Benign prostatic hyperplasia and prostate cancer is an internationally important health problem of the man,particularly in developed countries.The aim of this exploratory study was to evaluate whether significant ...
Scientific work was funded by Ministry of Science and Higher Education Republic of Poland from the budget for science in the years 2016-2020 as a research project within the program "Diamond Grant" (0184/DIA/2016/45)
Aim:Prostate cancer(PCa)is the most commonly diagnosed non-skin cancer among men.Serum prostate-specific antigen level is used as a standard PCa biomarker for over 20 years.However,it has only 33%specificity and 86%se...
Hypoxia is a well-established characteristic of prostate tumors and is now recognised as a major contributory factor to both tumor progression and increased resistance to therapy.One strategy to target hypoxic tumor c...
In a normal prostate,the process of controling cell death is essential to maintain tissue homeostasis and its inhibition may lead to the development of cancer.Androgen receptor signaling plays pivotal roles in the pro...