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RNA_INTERFERENCE: 作品数：484被引量：1982H指数：19; 导出分析报告; 相关作者：潘玉琴王书奎何帮顺李瑞俞强更多>>; 相关机构：江苏省人民医院中山大学清华大学南京师范大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>

RNA interference-mediated osteoprotegerin silencing increases the receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio and promotes osteoclastogenesis: 《World Journal of Stem Cells》2025年第4期64-78,共15页Song-Guan Wei Hui-Hong Chen Liu-Rong Xie Yuan Qin Yu-Ying Mai Lin-Hui Huang Hong-Bing Liao; Supported by the National Natural Science Foundation of China,No.82160192;and Guangxi Science and Technology Program,No.2023AB23037.; BACKGROUND In vivo degradation of bone scaffolds is significantly influenced by osteoclast(OC)activity,which is orchestrated by the interplay between receptor activator of nuclear factor-kappa B ligand(RANKL)and osteo...; 关键词：OSTEOPROTEGERIN Receptor activator of nuclear factor-kappa B ligand Bone marrow-derived mesenchymal stem cells RNA interference OSTEOCLAST Bone scaffold

Targeting Syntaxin 1A via RNA interference inhibits feeding and midgut development in Locusta migratoria: 《Insect Science》2025年第2期385-397,共13页Xiaojian Liu Ya Gao Yao Li Jianzhen Zhang; supported by the National Key R&D Program of China(2022YFD1700200);the Natural Science Foundation of Shanxi Province,China(20210302123440);the Fund for Shanxi“1331 Project”and the Graduate Education Innovation Project of Shanxi Province,China(2023SJ033).; Syntaxin 1A(Syx1A)has diverse and indispensable functions in animals.Pre-vious studies have mainly focused on the roles of Syx1A in Drosophila,and so how Syx1A operates during the development of other insects remains ...; 关键词：insulin/mTOR pathway Locusta migratoria midgut development RNAi Syntaxin 1A

Knockdown of vitellogenin receptor based on minute insect RNA interference methods affects the initial mature egg load in the pest natural enemy Trichogramma dendrolimi: 《Insect Science》2025年第2期487-500,共14页Cheng-Xing Wang Hui-Qiao Bao Zhi-Chao Yan Jie Wang Su Wang Yuan-Xi Li; supported by the National Natu-ral Science Foundation of China(32172483);Jiangsu Agriculture Science and Technology Innovation Fund(CX(22)3012);National Key R&D Plan of China(2023YFD1400605).; Vitellogenin receptor(VgR)plays a crucial role in oogenesis by mediating en-docytosis of vitellogenin and a portion of the yolk proteins in many insect species.How-ever,the function of VgR in minute parasitoid wasps i...; 关键词：initial mature egg load ovarian dysplasia parasitic capacity RNA interference vitellogenin receptor

RNAi-mediated pest control targeting the Troponin I(wupA)gene in sweet potato weevil,Cylas formicarius: 《Insect Science》2025年第2期631-648,共18页Mengjun Zhang Xiaxuan Zhang Tingting Chen Yonglin Liao Bin Yang Guirong Wang; supported from the National Key R&D Program of China(2022YFE0116500);the Shen zhen Science and Technology Program(Grant No.KQTD20180411143628272)and Agricultural Science and Technology Innovation Program(ASTIP).; The sweet potato weevil(Cylas formicarius)is a critical pest producing enor-mous global losses in sweet potato crops.Traditional pest management approaches for sweet potato weevil,primarily using chemical pesticides,c...; 关键词：BIOPESTICIDES gene knockdown IPM pest management RNA interference wupA

Drug development for chronic hepatitis B functional cure:Recent progress: 《World Journal of Hepatology》2025年第4期31-42,共12页Ting Liu He Wang Yue Zhao Ying-Xin Wang Xue Xing Peng Gao; Chronic hepatitis B virus(HBV)infection affects approximately 254 million individuals globally,contributing to significant morbidity and mortality due to HBV-related liver failure and cirrhosis,which result in million...; 关键词：Chronic hepatitis B infection Therapeutic targets Monoclonal antibody RNA interference IMMUNOMODULATORS

Adaptive evolution of traits for parasitism and pathogen transmission potential in bat flies: 《National Science Review》2025年第3期39-52,共14页Guangping Huang Xing Liu Xin Huang Chuang Gao Zhilin Wang Junxia Li Xiaocui Wei Wen-Hua Yu Yi Wu Ying Liu Jiang Feng Yang Li Fuwen Wei; supported by the National Natural Science Foundation of China(32192420);the Major Program of the Natural Science Foundation of Jiangxi Province of China(20233ACB209001 and 2023SSY02081);the Special Foundation for National Science and Technology Basic Research Program of China(2021FY100300);the National Key R&D Program of China(2023YFF1305402).; Deciphering the mechanisms underlying the transmission and spillover of zoonoses from reservoir hosts is essential in preventing future global pandemics.Bat flies-obligate blood-feeding ectoparasites of bats-are known...; 关键词：bat fly BAT host-pathogen interactions ECTOPARASITES adaptive evolution virus-host dynamics antiviral RNA interference

Point mutations of Dicer2 conferred Fusarium asiaticum resistance to RNAi-related biopesticide: 《Journal of Integrative Agriculture》2025年第2期623-637,共15页Kaixin Gu Ran Wei Yidan Sun Xiaoxin Duan Jing Gao Jianxin Wang Yiping Hou Mingguo Zhou Xiushi Song; funded by the National Natural Science Foundation of China(32372585);the Natural Science Foundation of Jiangsu Province,China(BK20231471);the National Training Program of Innovation and Entrepreneurship for Undergraduates,China(202210307013Z)。; The use of RNA interference(RNAi)technology to control pests is explored by researchers globally.Even though RNA is a new class of pest control compound unlike conventional chemical pesticides,the evolution of pest re...; 关键词：RNA interference DSRNA Dicer2 point mutation RESISTANCE Fusarium asiaticum

Functions and applications of RNA interference and small regulatory RNAs被引量：1: 《Acta Biochimica et Biophysica Sinica》2025年第1期119-130,共12页Xuezhu Feng Shouhong Guang; supported by the grants from the National Key R&D Program of China(Nos.2022YFA1302700 and 2019YFA0802600);the National Natural Science Foundation of China(Nos.32230016,32270583,32070619,2023M733425 and 32300438);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB39010600);the Research Funds of Center for Advanced Interdisciplinary Science and Biomedicine of IHM(No.QYPY20230021);the Fundamental Research Funds for the Central Universities.; Small regulatory RNAs play a variety of crucial roles in eukaryotes,influencing gene regulation,developmental timing,antiviral defense,and genome integrity via a process termed RNA interference(RNAi).This process invo...; 关键词：RNAI SIRNA MICRORNA PIRNA

Role of dsRNA-Based Insecticides in Agriculture:Current Scenario and Future Prospects: 《Phyton-International Journal of Experimental Botany》2024年第12期3217-3235,共19页Pratyush Kumar Das Satyabrata Nanda; Insect pests cause severe crop damage,resulting in substantial economic losses and threats to global food security.Conventional insecticides are low-cost chemical agents that kill the target insects and some non-speci...; 关键词：DSRNA INSECTICIDE integrated pest management RNA interference sustainable agriculture

Liposome-based RNAi delivery in honeybee for inhibiting parasite Nosema ceranae被引量：1: 《Synthetic and Systems Biotechnology》2024年第4期853-860,共8页Yue Qi Chen Wang Haoyu Lang Yueyi Wang Xiaofei Wang Hao Zheng Yuan Lu; supported by the National Natural Science Foundation of China(32170495,22278241);the National Key R&D Program of China(2018YFA0901700);a grant from the Institute Guo Qiang,Tsinghua University(2021GQG1016);the Department of Chemical Engineering-iBHE Joint Cooperation Fund.; Nosema ceranae,a parasite that parasitizes and reproduces in the gut of honeybees,has become a serious threat to the global apiculture industry.RNA interference(RNAi)technology can be used to inhibit N.ceranae growth ...; 关键词：HONEYBEE LIPOSOME Nosema ceranae RNA interference

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