SIGNAL_TRANSDUCTION

作品数:482被引量:3037H指数:28
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Identification and Expression Analysis of Abscisic Acid Signal Transduction Genes in Hemp Seeds
《Phyton-International Journal of Experimental Botany》2023年第7期2087-2103,共17页Cong Hou Kang Ning Xiuye Wei Yufei Cheng Huatao Yu Haibin Yu Xia Liu Linlin Dong 
funded by the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ13-YQ049);the Scientific Research Project of Hainan Academician Innovation Platform(SQ2021PTZ0052);the National Key R&D Program of China from the Ministry of Science and Technology of China(No.2019YFC1711100).
Abscisic acid(ABA)is involved in regulating diverse biological processes,but its signal transduction genes and roles in hemp seed germination are not well known.Here,the ABA signaling pathway members,PYL,PP2C and SnRK...
关键词:Hemp seeds abscisic acid seed germination PYL-PP2C-SnRK2 gene expression 
Roles of flotillins in tumors被引量:2
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2018年第3期171-182,共12页Xu-xu LIU Wei-dong LIU Lei WANG Bin ZHU Xiao SHI Zi-xuan PENG He-cheng ZHU Xing-dong LIU Mei-zuo ZHONG Dan XIE Mu-sheng ZENG Cai-ping REN 
Project supported by the National Natural Science Foundation of China(Nos.81773179 and 81272972);the National Basic Research Program(973)of China(No.2010CB833605);the Hunan Provincial Science and Technology Department(Nos.2013FJ4010 and2014FJ6006);the Open-End Fund for the Valuable and Precision Instruments of Central South University(Nos.CSUZC201634 and CSUZC201638);the Natural Science Foundation of Hunan Province(No.2016JJ2172);the National College Students Innovation Projects(Nos.201610533264 and 201610533538),China
The identification and use of molecular biomarkers have greatly improved the diagnosis and treatment of malignant tumors. However, a much deeper understanding of oncogenic proteins is needed for the benefit to cancer ...
关键词:Flotillins TUMOR Lipid raft protein Signal transduction 
Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition model
《Frontiers of Medicine》2016年第3期311-319,共9页Jiansong Huang Yulan Zhou Xiaoyu Su Yuanjing Lyu Lanlan Tao Xiaofeng Shi Ping Liu Zhangbiao Long Zheng Ruan Bing Xiao Wenda Xi Quansheng Zhou Jianhua Mao Xiaodong Xi 
We thank all the laboratory members for helpful discussion. This work was supported by grants from National Natural Science Foundation of China (No. 81270594), National Basic Research Program of China (No. 2012CB518000, No. 2013CB966800) and National Natural Science Foundation of China (No. 81070414). Jiansong Huang is a recipient of a fellowship from The China Postdoctoral Science Foundation (No. 2013M531185).
We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e.,...
关键词:integrin β3 signal transduction tmns-dominant inhibition model 
Immune Regulation of Interleukin-27 in Malignant Pleural Effusion被引量:4
《Chinese Medical Journal》2015年第14期1932-1941,共10页Shi Li Wen-Jie You Jian-Chu Zhang Qiong Zhou Huan-Zhong Shi 
Source of Support: This work was supported by grants in part from National Basic Research Program of China (No. 2012CB518706); in part from National Natural Science Foundation of China (No. 81272591 and No. 81470274). Conflict of Interest: None declared.
Background: lnterlcukin (IL)-27 has been reported to have anti-proliferate and anti-angiogenic activities on cancer cells. However, the involvement of IL-27 in malignant pleural effusion (MPE) remains unknown. Th...
关键词:INTERLEUKIN-27 Lung Cancer Malignant Pleural Effusion Signal Transduction 
Focusing on the Focus: What Else beYOnd the Master Switches for Polar Cell Growth?被引量:2
《Molecular Plant》2015年第4期582-594,共13页Yuan Qin Juan Dong 
Y.Q. is supported by the Ministry of Science and Technology of China (2011CB944603; 2012C8944801), National Natural Science Foundation of China (31170290; 31470284), and Program for New Century Excellent Talents in Fujian Province University (JA14096). J.D. is supported by grants front the U.S. National Institute of General Medical Sciences (R01GM 109080) and Rutgers University.ACKNOWLEDGMENTS We apologize for the work not cited in tills review due to the size Iirnit. No conflict of interest declared,
Cell polarity, often associated with polarized cell expansion/growth in plants, describes the uneven distribution of cellular components, such as proteins, nucleic acids, signaling molecules, vesicles, cytoskeletal el...
关键词:cell expansion CYTOSKELETON polarity polarity determination signal transduction 
OsHK3 is a crucial regulator of abscisic acid signaling involved in antioxidant defense in rice被引量:2
《Journal of Integrative Plant Biology》2015年第2期213-228,共16页Feng Wen Tingting Qin Yao Wang Wen Dong Aying Zhang Mingpu Tan Mingyi Jiang 
supported by the National Basic Research Program of China (2012CB114306);the National Natural Science Foundation of China (31070254 and 31271631);the Fundamental Research Funds for the Central Universities (KYZ201157 and KYTZ201402);the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions;the Research Fund for the Doctoral Program of Higher Education of China (20130097110025)
In this study, the role of the rice (Oryza sativa L.) histidine kinase OsHK3 in abscisic acid (ABA)-induced antioxidant defense was investigated. Treatments with ABA, H2O2, and polyethylene glycol (PEG) induced ...
关键词:Abscisic acid antioxidant defense histidine kinase signal transduction RICE 
Decoding the phosphorylation code in Hedgehog signal transduction被引量:9
《Cell Research》2013年第2期186-200,共15页Yongbin Chen Jin Jiang 
We apologize to those whose work we could not cite due to space limitations. Y Chen is supported by grams from the National Natural Science Foundation of China (31271579), National Key Basic Research Program of China (2013CB910900), American Heart Association postdoctoral fellowship (10POST3640046), Kunming Institute of Zoology startup foundation and Chinese Academy of Sciences. J Jiang is supported by grants from NIH (GM067045 and GM061269), CPRIT (RPI00561) and Welch foundation 0-1603), and is a Eugene McDermott Endowed Schol-ar of Biomedical Science at UTSW.
Hedgehog (Hh) signaling plays pivotal roles in embryonic development and adult tissue homeostasis, and its de-regulation leads to numerous human disorders including cancer. Binding of Hh to Patched (Ptc), a twelve...
关键词:HEDGEHOG SMO GLI signal transduction PHOSPHORYLATION development cancer 
Novel insights for high mobility group box 1 proteinmediated cellular immune response in sepsis:A systemic review被引量:20
《World Journal of Emergency Medicine》2012年第3期165-171,共7页Li-feng Huang Yong-ming Yao Zhi-yong Sheng 
supported,in part,by grants from the National Natural Science Foundation(Nos.81130035,30901561,30971192,81071545);the National Basic Research Program of China(No.2012CB518102);the China Postdoctoral Science Foundation(Nos.20100480347,201104125)
High mobility group box 1 protein (HMGB1) is a highly conserved, ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted into the extracellular milieu and acts as a proinflammatory...
关键词:High mobility group box 1 protein SEPSIS Immunological effect CYTOKINE Signal transduction 
Germinal center kinases in immune regulation被引量:1
《Cellular & Molecular Immunology》2012年第6期439-445,共7页Hailei Yin Zhubing Shi ShiJiao Cuicui Chen Wenjia Wang Mark I Greene Zhaocai Zhou 
This work was supported by the 973 Program of the Ministry of Science and Technology of China (2010CB529700 and 2012CB910204), the National Natural Science Foundation of China (NSFC10979005 and NSFC30970566) and the Science and Technology Commission of Shanghai Municipality (11JC14140000). Dr ZZ is a scholar of the Hundred Talents Program of the Chinese Academy of Sciences. Dr Greene is supported by grants from the NIH, NCI, the Abramson Family Research Institute and the BCRF.
Germinal center kinases (GCKs) participate in a variety of signaling pathways needed to regulate cellular functions including apoptosis, cell proliferation, polarity and migration. Recent studies have shown that GCK...
关键词:germinal center kinases immune regulation signal transduction 
OsDMI3 Is a Novel Component of Abscisic Acid Signaling in the Induction of Antioxidant Defense in Leaves of Rice被引量:11
《Molecular Plant》2012年第6期1359-1374,共16页Ben Shi Lan Ni Aying Zhang Jianmei Cao Hong Zhang Tingting Qin Mingpu Tan Jianhua Zhang Mingyi-Jiang 
the National Basic Research Program of China,the National Natural Science Foundation of China,the Fundamental Research Funds for the Central Universities,the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions,the Natural Science Foundation of Jiangsu Province,the Research Fund for the Doctoral Program of Higher Education of China,the Program for New Century Excellent Talents in University,the grant from the Education Department of Jiangsu
Ca^2+ and calmodulin (CAM) have been shown to play an important role in abscisic acid (ABA)-induced anti- oxidant defense. However, it is unknown whether Ca^2+/CaM-dependent protein kinase (CCaMK) is involved ...
关键词:OsDMI3 abscisic acid antioxidant defense H202 oxidative stress signal transduction. 
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