funded by the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ13-YQ049);the Scientific Research Project of Hainan Academician Innovation Platform(SQ2021PTZ0052);the National Key R&D Program of China from the Ministry of Science and Technology of China(No.2019YFC1711100).
Abscisic acid(ABA)is involved in regulating diverse biological processes,but its signal transduction genes and roles in hemp seed germination are not well known.Here,the ABA signaling pathway members,PYL,PP2C and SnRK...
Project supported by the National Natural Science Foundation of China(Nos.81773179 and 81272972);the National Basic Research Program(973)of China(No.2010CB833605);the Hunan Provincial Science and Technology Department(Nos.2013FJ4010 and2014FJ6006);the Open-End Fund for the Valuable and Precision Instruments of Central South University(Nos.CSUZC201634 and CSUZC201638);the Natural Science Foundation of Hunan Province(No.2016JJ2172);the National College Students Innovation Projects(Nos.201610533264 and 201610533538),China
The identification and use of molecular biomarkers have greatly improved the diagnosis and treatment of malignant tumors. However, a much deeper understanding of oncogenic proteins is needed for the benefit to cancer ...
We thank all the laboratory members for helpful discussion. This work was supported by grants from National Natural Science Foundation of China (No. 81270594), National Basic Research Program of China (No. 2012CB518000, No. 2013CB966800) and National Natural Science Foundation of China (No. 81070414). Jiansong Huang is a recipient of a fellowship from The China Postdoctoral Science Foundation (No. 2013M531185).
We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e.,...
Source of Support: This work was supported by grants in part from National Basic Research Program of China (No. 2012CB518706); in part from National Natural Science Foundation of China (No. 81272591 and No. 81470274). Conflict of Interest: None declared.
Background: lnterlcukin (IL)-27 has been reported to have anti-proliferate and anti-angiogenic activities on cancer cells. However, the involvement of IL-27 in malignant pleural effusion (MPE) remains unknown. Th...
Y.Q. is supported by the Ministry of Science and Technology of China (2011CB944603; 2012C8944801), National Natural Science Foundation of China (31170290; 31470284), and Program for New Century Excellent Talents in Fujian Province University (JA14096). J.D. is supported by grants front the U.S. National Institute of General Medical Sciences (R01GM 109080) and Rutgers University.ACKNOWLEDGMENTS We apologize for the work not cited in tills review due to the size Iirnit. No conflict of interest declared,
Cell polarity, often associated with polarized cell expansion/growth in plants, describes the uneven distribution of cellular components, such as proteins, nucleic acids, signaling molecules, vesicles, cytoskeletal el...
supported by the National Basic Research Program of China (2012CB114306);the National Natural Science Foundation of China (31070254 and 31271631);the Fundamental Research Funds for the Central Universities (KYZ201157 and KYTZ201402);the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions;the Research Fund for the Doctoral Program of Higher Education of China (20130097110025)
In this study, the role of the rice (Oryza sativa L.) histidine kinase OsHK3 in abscisic acid (ABA)-induced antioxidant defense was investigated. Treatments with ABA, H2O2, and polyethylene glycol (PEG) induced ...
We apologize to those whose work we could not cite due to space limitations. Y Chen is supported by grams from the National Natural Science Foundation of China (31271579), National Key Basic Research Program of China (2013CB910900), American Heart Association postdoctoral fellowship (10POST3640046), Kunming Institute of Zoology startup foundation and Chinese Academy of Sciences. J Jiang is supported by grants from NIH (GM067045 and GM061269), CPRIT (RPI00561) and Welch foundation 0-1603), and is a Eugene McDermott Endowed Schol-ar of Biomedical Science at UTSW.
Hedgehog (Hh) signaling plays pivotal roles in embryonic development and adult tissue homeostasis, and its de-regulation leads to numerous human disorders including cancer. Binding of Hh to Patched (Ptc), a twelve...
supported,in part,by grants from the National Natural Science Foundation(Nos.81130035,30901561,30971192,81071545);the National Basic Research Program of China(No.2012CB518102);the China Postdoctoral Science Foundation(Nos.20100480347,201104125)
High mobility group box 1 protein (HMGB1) is a highly conserved, ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted into the extracellular milieu and acts as a proinflammatory...
This work was supported by the 973 Program of the Ministry of Science and Technology of China (2010CB529700 and 2012CB910204), the National Natural Science Foundation of China (NSFC10979005 and NSFC30970566) and the Science and Technology Commission of Shanghai Municipality (11JC14140000). Dr ZZ is a scholar of the Hundred Talents Program of the Chinese Academy of Sciences. Dr Greene is supported by grants from the NIH, NCI, the Abramson Family Research Institute and the BCRF.
Germinal center kinases (GCKs) participate in a variety of signaling pathways needed to regulate cellular functions including apoptosis, cell proliferation, polarity and migration. Recent studies have shown that GCK...
the National Basic Research Program of China,the National Natural Science Foundation of China,the Fundamental Research Funds for the Central Universities,the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions,the Natural Science Foundation of Jiangsu Province,the Research Fund for the Doctoral Program of Higher Education of China,the Program for New Century Excellent Talents in University,the grant from the Education Department of Jiangsu
Ca^2+ and calmodulin (CAM) have been shown to play an important role in abscisic acid (ABA)-induced anti- oxidant defense. However, it is unknown whether Ca^2+/CaM-dependent protein kinase (CCaMK) is involved ...