SMOOTH_MUSCLE_CELLS

作品数：141被引量：376H指数：10
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  • 期刊=Asian Journal of Andrologyx
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N-acetylcysteine ameliorates erectile dysfunction in rats with hyperlipidemia by inhibiting oxidative stress and corpus cavernosum smooth muscle cells phenotypic modulation
《Asian Journal of Andrology》2024年第1期99-106,共8页Wei Ding Jun-Hong Fan Li-Ren Zhong Nan-Xiong Wang Lu-Hao Liu Hai-Bo Zhang Li Wang Ming-Qiang Wang Bing-Lin He An-Yang Wei 
This work is supported by a grant from the National Natural Science Foundation of China(No.82060809);the Natural Science Foundation of Guangdong Province(No.2017A030313453 and No.2018A030313638);Guangzhou Basic and Applied Basic Research Foundation(No.202102020417).
Hyperlipidemia is a major risk factor for erectile dysfunction(ED).Oxidative stress and phenotypic modulation of corpus cavernosum smooth muscle cells(CcSMCs)are the key pathological factors of ED.N-acetylcysteine(NAC...
关键词：erectile dysfunction HYPERLIPIDEMIA N-ACETYLCYSTEINE oxidative stress henotypic modulation 
Experimental investigation of early assessment of corpora cavernosa fibrosis with two-dimensional shear wave elastography被引量：1
《Asian Journal of Andrology》2022年第2期207-212,共6页Li Yu Wan-Ting Rao Jing-Dong Tang Jin-Fang Xing 
This study was supported by grants from the Scientific Research Foundation of Shanghai Pudong Hospital,Fudan University Pudong Medical Center(No.YJRCJJ201804);the Outstanding Clinical Discipline Project of Shanghai Pudong(NO.PWYgy-2018-08);the Scientific Research Foundation of Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling(NO.zdsys202008).
This study explored the usefulness of two-dimensional shear wave elastography(2D-SWE)in the early assessment of corpora cavernosa fibrosis(CCF).New Zealand male rabbits were randomly assigned to an experimental group ...
关键词：collagen type I collagen type III ELASTOGRAPHY PENIS smooth muscle cells 
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection被引量：3
《Asian Journal of Andrology》2021年第3期249-258,共10页Xiao-Feng Yue Chong-Xing Shen Jian-Wu Wang Lin-Yong Dai Qiang Fang Lei Long Yi Zhi Xue-Ru Li Ya-Wei Wang Gu-Fang Shen Zu-Juan Liu Chun-Meng Shi Wei-Bing Li 
the National Key Research and Development Program(2016Y FC1000805);University Innovation Team Building Program of Chongqing(CXTDG201602020);Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202000433).
This study aimed to evaluate the therapeutic effect of IR-61,a novel mitochondrial heptamethine cyanine dye with antioxidant effects,on diabetes mellitus-induced erectile dysfunction(DMED).Eight-week-old male Sprague-...
关键词：corpus cavernosum smooth muscle cells diabetes erectile dysfunction IR-61 MITOCHONDRIA 
Effects of Ginkgo biloba extracts with mirodenafil on the relaxation of corpus cavernosal smooth muscle and the potassium channel activity of corporal smooth muscle cells被引量：1
《Asian Journal of Andrology》2011年第5期742-746,共5页Jung Jun Kim Deok Hyun Han Soo Hyun Lim Tae Hun Kim Mee Ree Chae Kyung Jin Chung Sung Chul Kam Ju-Hong Jeon Jong Kwan Parks Sung Won Lee 
In this study, we investigated the effects of a combination of Ginkgo biloba extracts （GBE） and phosphodiesterase type 5 （PDE-5） inhibitors on the muscular tone of the corpus cavernosum and potassium channel activ...
关键词：calcium-activated potassium channels erectile dysfunction Ginkgo biloba phosphodiesterase inhibitors smooth muscles 
Effects of ethanol on the tonicity of corporal tissue and the intracellular Ca^2＋ concentration of human corporal smooth muscle cells被引量：1
《Asian Journal of Andrology》2010年第6期890-898,共9页Sung Chul Kam Mee Ree Chae Ji Young Kim Seol Ho Choo Deok Hyun Han Sung Won Lee 
Heavy alcohol consumption is associated with an increased risk of erectile dysfunction （ED）; however, the acute effects of ethanol （EtOH） on penile tissue are not fully understood. We sought to investigate the eff...
关键词：ALCOHOL Ca^2＋-activated potassium channel corporal smooth muscle penile erection 
Effect of tankyrase 1 on autophagy in the corpus cavernosum smooth muscle cells from ageing rats with erectile dysfunction and its potential mechanism被引量：12
《Asian Journal of Andrology》2010年第5期744-752,共9页Jian Zhang Xiao-Jun Wu De-Xiang Zhuo Tao Liu Wei-Ren Li Ze-Bin Mao Zhong-Cheng Xin 
Acknowledgment We are grateful to Dr Tamotsu Yoshimori for providing the GFP-LC3 plasmid and Dr H. Seimiya for providing the tankyrase 1 plasmid. This study was supported by the National Natural Science Foundation of China （No. 30772285） and Beijing Municipal Commission of Science Technology, China （No. Z080507030808011）.
This study compared tankyrase 1 expression and autophagy quantity between erectile dysfunction （ED） and non-ED rats＇ corpus cavernosum smooth muscle cells （CSMCs）. This study aslo explored the effect and possible...
关键词：ageing AUTOPHAGY corpora cavernosum corpus cavemosum smooth muscle cells erectile dysfunction SENILE TANKYRASE 
Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells被引量：7
《Asian Journal of Andrology》2008年第6期905-913,共9页Matthew Hotston Jamie Y. Jeremy Jonathon Bloor Nick S. Greaves Raj Persad Gianni Angelini Nilima Shukla 
Aim： To study the effects of homocysteine and copper on type 5 phosphodiesterase （PDE5） expression in cavemosai vascular smooth muscle cells （CVSMCs） and to investigate superoxide （O2-） derived from nicotinamid...
关键词：erectile dysfunction superoxide PDE5 SILDENAFIL 
Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbits
《Asian Journal of Andrology》2006年第4期405-409,513-514,共5页Ji-Hong Liu Jun Chen Tao Wang Bo Liu Jun Yang Xiao-Wen Chen Shao-Gang Wang Chun-Ping Yin Zhang-Qun Ye 
Aim:To study the relaxation mechanisms of tetrandrine(Tet)on the corpus cavernosum smooth muscle.Methods: The corpus cavernosum smooth muscle cells from New Zealand white rabbits were cultured in vitro.[Ca^(2+)]_i was...
关键词：TETRANDRINE PENIS smooth muscle cell free calcium corpus cavernosum erectile dysfunction 
Androgen and prostatic stroma被引量：11
《Asian Journal of Andrology》2003年第1期19-26,共8页Yuan-Jie NIU, Teng-Xiang MA, Ju ZHANG, Yong XU, Rui-Fa HAN, Guang SUNDepartment of Prostatic Disease, Tianjin Institute of Urologial Surgery, Tianjin Medical University,Tianjin 300211, China 
PresentedattheFirstAsia-PacificForumonAndrology,17-21October2002,Shanghai,China.
Aim: To investigate the effect of androgen on the proliferation, differentiation and regression of canine prostatic stromal cells in vivo and human stromal cells in vitro. Methods: Twenty-two dogs, including...
关键词：androgen CASTRATION androgen receptor prostatic stroma smooth muscle cells 
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