supported by the Scientific Research Projects Coordination Unit of Istanbul University(No.13930).
Spermatozoa have a highly complex RNA profile.Several of these transcripts are suggested as biomarkers for male infertility and contribute to early development.To analyze the differences between sperm RNA quantity and...
This work was supported by the National Key R&D Program of China(No.2018YFC1005001);the Zhongshan Hospital Youth Fund(No.2019ZSQN57);the National Natural Science Foundation of China(No.81971345).
Advanced paternal age has been overlooked,and its effect on fertility remains controversial.Previous studies have focused mainly on intracytoplasmic sperm injection(ICSI)cycles in men with oligozoospermia.However,few ...
A genetically and functionally proficient gamete is essential for normal fertilization and embryonic development.Any change in gamete health affects fertilization and subsequent events,including embryonic development,...
Evidence has shown that the health status of a pregnant woman can affect her children’s health over a long time and even to adulthood.Lousy diet habits,such as overeating before conception or during pregnancy that ca...
This work was supported by National Natural Science Foundation of China(No.31472054);the National Key Research and Development Program of China(2016YFC1000600).
Slow freezing is the most commonly used technique for the cryopreservation of spermatozoa in clinical practice.However,it has been shown to have a negative impact on sperm function and structure.Vitrification as a suc...
Oxidative stress is prevalent among infertile men and is a significant cause of sperm DNA damage.Since sperm DNA damage may reduce embryo quality and increase miscarriage rates,it is possible that untreated sperm oxid...
Peking Post-doctoral Research Fund(EE 2019-50);Peking University International Hospital Research Funds(No.YN2019QN13);NHC Key Laboratory of Family Planning and Healthy/key laboratory of reproductive medicine of Hebei provincial(SZ-202006).
Sperm cryopreservation is useful in assisted reproductive technology and male fertility preservation.However,freezing and thawing significantly reduces the total and progressive motility of human spermatozoa.In the pr...
Sperm DNA fragmentation(SDF)has been linked with male infertility,and previous studies suggest that SDF can have negative influence on pregnancy outcomes with assisted reproduction.We performed a retrospective review ...
An increased amount of DNA fragme ntation in the spermatozoa(SDF)is linked to male in fertility.The Sperm Chromati n Structure Assay(SCSA)is widely used for analysis of SDF.However,the current software(SCSASoftR)linke...
We thank the financial support from National Natural Science Foundation of China(81401252);MerckSerono China Research Fund for Fertility Experts.
Background:To study the effects of cryopreservation on human sperm glycocalyx.Methods:The lectin binding profilings of sperm after freeze-thaw were compared by lectin microarray.Results:CryoSperm^(TM) and direct fumig...