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作品数：163被引量：415H指数：9
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相关领域：医药卫生农业科学更多>>
相关作者：陆丽丽刘丹赵艳敏饶纯倪毅然更多>>
相关机构：内蒙古科技大学三峡大学天津市泰达医院中南大学湘雅三医院更多>>
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Colon cancer-associated transcript 1(CCAT1):A potential novel target in cancer therapy
《Chinese Medical Journal》2024年第17期2128-2130,共3页Jinjie Ma Junpeng Pei Xueping Zhang Xiao Bai Siqi Ding Dongqiu Dai 
supported by the grant from the National Natural Science Foundation of China(No.81972322).
To the Editor:Long non-coding RNAs(lncRNAs)are a class of RNA molecules comprising more than 200 nucleotides in length,which possess negligible ability to encode functional proteins.LncRNAs are involved in several cel...
关键词：CCAT1 COLON CANCER 
Long non-coding RNA colon cancer-associated transcript 1-Vimentin axis promoting the migration and invasion of HeLa cells被引量：1
《Chinese Medical Journal》2023年第19期2351-2361,共11页Zhangfu Li Jiangbei Yuan Qingen Da Zilong Yan Jianhua Qu Dan Li Xu Liu Qimin Zhan Jikui Liu 
supported by grants from the Sanming Project of Medicine in Shenzhen(No.SZSM201612021);Special Foundation for Science and Technology Development of Guangdong Province(No.2017B090904010);Scientific Research Project of Health and Family Planning Commission of Shenzhen Municipality(No.SZXJ2018086);the Science and Technology Development Fund Project of Shenzhen(Nos.JCYJ20190809100217290 and JCYJ20190809095801653)
Background:Long non-coding RNA colon cancer-associated transcript 1(CCAT1)is involved in transforming multiple cancers into malignant cancer types.Previous studies underlining the mechanisms of the functions of CCAT1 ...
关键词：lncRNA CCAT1 RAP-MS RNA binding protein VIMENTIN MIGRATION INVASION 
Long non-coding RNA colon cancer-associated transcript 2:role and function in human cancers被引量：2
《Chinese Medical Journal》2022年第23期2785-2797,共13页Shuoshuo Ma Wenjing Wang Dengyong Zhang Guanru Zhao Zheng Lu 
Anhui Province Science Foundation(No.2008085MH256).
Long non-coding RNAs(lncRNAs)are a family of non-protein-coding RNAs that span a length of over 200 nucleotides.Research reports have illustrated that lncRNAs are involved in various cellular processes and that their ...
关键词：CANCER CCAT2 Long non-coding RNA Colon cancer-associated transcript 2 
Identification and characterization of a novel group of natural antisense transcripts from RNA1.2 gene locus of human cytomegalovirus
《Chinese Medical Journal》2019年第13期1591-1598,共8页Bing-Yang Liu Yan-Ping Ma Ying Qi Yu-Jing Huang Zhong-Yang Liu Meng-Qing Lu Qiang Ruan 
grants from the National Natural Science Foundation of China(Nos.81672028 and 81371788);the Outstanding Scientific Fund of Shengjing Hospital.
Background:Natural anti-sense transcripts(NATs),which are transcribed from the complementary DNA strand of annotated genes,exert regulatory function of gene expression.Increasing studies recognized anti-sense transcri...
关键词：HUMAN CYTOMEGALOVIRUS RNA1.2 NATURAL anti-sense TRANSCRIPT 
Effects of Glucocorticoid?Induced Transcript 1 Gene Deficiency on Glucocorticoid Activation in Asthmatic Mice被引量：5
《Chinese Medical Journal》2018年第23期2817-2826,共10页Cheng-Ping Hu Qiu-Fen Xun Xiao-Zhao Li Xin-Yue Hu Ling Qin Ruo-Xi He Jun-Tao Feng 
grants from the National Natural Science Foundation of China (No.81270080and No.81670027).
Background: Glucocorticoid (GC) is the first?line therapy for asthma, but some asthmatics are insensitive to it. Glucocorticoid?induced transcript 1 gene (GLCCI1) is reported to be associated with GCs efficiency in as...
关键词：Asthma GLUCOCORTICOID Receptor Glucocorticoid-Induced TRANSCRIPT 1 GLUCOCORTICOIDS MITOGEN-ACTIVATED Protein Kinase Phosphatase-1 
Biological Function and Mechanism of Long Noncoding RNAs Nuclear-Enriched Abundant Transcript I in Development of Cervical Cancer被引量：5
《Chinese Medical Journal》2018年第17期2063-2070,共8页Hui-Ling Wang Shun-Yu Hou Hai-Bo Li Jian-Ping Qiu Le Bo Cai-Ping Mao 
This study was supported by grants from the National Natural Science Foundation of China （No. 81370719 and No. 81671535）, the Science Foundation of Jiangsu （No. BE2015642, and No. WSW023）, the Jiangsu Key Discipline of Human Assisted Reproduction Medicine Foundation （No. FXK201749）, and the Jiangsu Provincial Medical Youth Talent of the Project of Invigorating Health Care through Science, Technology, and Education （No. ZDRCA2016044）.
Background： Accumulating documents have demonstrated that long noncoding RNAs （lncRNAs） play critical roles in tumorigenesis. As an lncRNA, nuclear-enriched abundant transcript 1 （NEAT1） has been identified to be...
关键词：Cervical Cancer Long Noncoding RNA Nuclear-Enriched Abundant Transcript 1 Migration PI3K/Akt SignalingPathway Proliferation 
Urinary Biomarkers for Chronic Kidney Disease with a Focus on Gene Transcript被引量：1
《Chinese Medical Journal》2017年第18期2251-2256,共6页Lin-Li Lyu Ye Feng Bi-Cheng Liu 
Objective：In the upcoming era of precision medicine,searching for the early,noninvasive biomarkers has been the cornerstone and major challenge in the management of chronic kidney disease （CKD）.Urine contains rich ...
关键词：Biomarkers  Chronic Kidney Disease Extracellular Vesicle Gene Transcript URINE 
Hypermethylation of testis derived transcript gene promoter significantly correlates with worse outcomes in glioblastoma patients
《Chinese Medical Journal》2013年第11期2062-2066,共5页WANG Li-jia BAI Yu BAO Zhao-shi CHEN Yan YAN Zhuo-hong ZHANG Wei ZHANG Quan-geng 
This work was supported in part by grants from the National Natural Science Foundation of China （No. 81201993, No. 81071626, No. 30872933）, National High Technology Research and Development Program （No. 2012AA02AS08）, International Science and Technology Cooperation Program （No. 2012DFA30470）.
Background Glioblastoma is the most common and lethal cancer of the central nervous system. Global genomic hypomethylation and some CpG island hypermethylation are common hallmarks of these malignancies, but the effec...
关键词：GLIOBLASTOMA promoter hypermethylation testis derived transcript microarray analysis outcome 
Detecting PML-RARα transcript in acute promyelocytic leukemia using real-time quantitative RT-PCR被引量：5
《Chinese Medical Journal》2007年第20期1803-1808,共6页ZHU Hong-hu LIU Yan-rong QIN Ya-zhen JIANG Bin SHAN Fu-xiang WU Shu-lan YANG Ping-di ZHAO Jie LU Dao-pei 
Background Real-time quantitative RT-PCR （RQ-PCR） assay has become a vital tool to monitor residual disease of leukemia, However, the complexity and standardization of RQ-PCR should never be overlooked and the resul...
关键词：real-time quantitative RT-PCR arsenics all-trans retinoic acid acute promyelocytic leukemia PML-RARΑ 
Effect of dihydrofolate reductase gene knock-down on the expression of heart and neural crest derivatives expressed transcript 2 in zebrafish cardiac development被引量：7
《Chinese Medical Journal》2007年第13期1166-1171,共6页SUN Shu-na GUI Yong-hao WANG Yue-xiang QIAN Lin-xi JIANG Qiu LIU Dong SONG Hou-yan 
Background Folic acid is very important for embryonic development and dihydrofolate reductase is one of the key enzymes in the process of fotic acid performing its biological function. Therefore, the dysfunction of di...
关键词：folic acid heart and neural crest derivatives expressed transcript 2 protein HEART development ZEBRAFISH 
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