TRANSCRIPTION_FACTOR

作品数：701被引量：3400H指数：25
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Single-cell transcriptomic landscape of human blood cells被引量：8
《National Science Review》2021年第3期37-47,共11页Xiaowei Xie Mengyao Liu Yawen Zhang Bingrui Wang Caiying Zhu Chenchen Wang Qing Li Yingying Huo Jiaojiao Guo Changlu Xu Linping Hu Aiming Pang Shihui Ma Una Wang Wenbin Cao Shulian Chen Qiuling Li Sudong Zhang Xueying Zhao Wen Zhou Hongbo Luo Guoguang Zheng Erlie Jiang Sizhou Feng Lixiang Chen Lihong Shi Hui Cheng Sha Hao Ping Zhu Tao Cheng 
supported by the Ministry of Science and Technology of China(2018YFA0107801,2016YFA0100600,2017YFA0103400);the National Key Research and Development Program of China(2018YFA0107804);the National Natural Science Foundation of China(81670106,81421002,81730006,81890990,81970104,32000803);the CAMS Initiative for Innovative Medicine(2017-I2M-1-015,2019-I2M-1-006,2016-I2M-1-017,2019-I2M-2-001)。
High throughput single-cell RNA-seq has been successfully implemented to dissect the cellular and molecular features underlying hematopoiesis.However,an elaborate and comprehensive transcriptome reference of the whole...
关键词：human hematopoietic cells lnc RNAs transcription factor single-cell RNA-seq 
Transcription factor ZmNAC126 plays an important role in transcriptional regulation of maize starch synthesis-related genes被引量：7
《The Crop Journal》2021年第1期192-203,共12页Qianlin Xiao Yayun Wang Hui Li Chunxia Zhang Bin Wei Yongbin Wang Huanhuan Huang Yangping Li Guowu Yu Hanmei Liu Junjie Zhang Yinghong Liu Yufeng Hu Yubi Huang 
supported by the National Natural Science Foundation of China(31571757);the National Key Basic Research Program of China(2014CB138202)。
Maize(Zea mays L.)is one of the most important food crops in the world,and starch is the main component of its endosperm.Transcriptional regulation plays a vital role in starch biosynthesis.However,it is not well unde...
关键词：MAIZE Starch synthesis ZmNAC126 CO-EXPRESSION Transcription regulation 
The transcription factor GATA10 regulates fertility conversion of a two-line hybrid tms5 mutant rice via the modulation of UbL40 expression^∞被引量：3
《Journal of Integrative Plant Biology》2020年第7期1034-1056,共23页Jing Jin Songtao Gui Qian Li Ying Wang Hongyuan Zhang Zhixuan Zhu Hao Chen Yueyang Sun Yu Zou Xingguo Huang Yi Ding 
We acknowledge Jinghong Yu(College of Life Sciences,Wuhan University,Wuhan,430072,China)for breeding rice WXS.This research is financially supported by National Natural Science Foundation of China(31471464);the funding from National Program on Key Basic Research Project of China(973 Program:2013CB126900).
The thermosensitive genic male sterile 5(tms5)mutation causes thermosensitive genic male sterility in rice(Oryza sativa)through loss of RNase ZS1 function,which influences ubiquitin fusion ribosomal protein L40(UbL40)...
关键词：SATIVA FERTILITY STERILE 
Oncoprotein HBXIP induces PKM2 via transcription factor E2F1 to promote cell proliferation in ER-positive breast cancer被引量：4
《Acta Pharmacologica Sinica》2019年第4期530-538,共9页Bo-wen Liu Tiarvjiao Wang Lei-lei Li Lu Zhang Yun-xia Liu Jin-yan Feng Yue Wu Fei-fei Xu Quan-sheng Zhang Ming-zhu Bao Wei-ying Zhang Li-hong Ye 
National Basic Research Program of China (973 Program, No. 2015CB553905);National Natural Science Foundation of China (Nos. 81372186 and 31670771);the Fundamental Research Funds for the Central Universities;Project of Prevention and Control of Key Chronic Non Infectious Diseases (No. 2016YFC1303401).
We have reported that hepatitis B X-interacting protein (HBXIP, also termed LAMT0R5) can act as an oncogenic transcriptional co-activator to modulate gene expression, promoting breast cancer development. Pyruvate kina...
关键词：HBXIP PKM2 E2F1 BREAST cancer proliferation 
Medicago AP2-Domain Transcription Factor WRI5a Is a Master Regulator of Lipid Biosynthesis and Transfer during Mycorrhizal Symbiosis被引量：15
《Molecular Plant》2018年第11期1344-1359,共16页Yina Jiang Qiujin Xie Wanxiao Wang Jun Yang Xiaowei Zhang Nan Yu Yun Zhou Ertao Wang 
the National Key Research and Development Program of China (2016YFA0500502);the National Science Foundation (31730103,31522007);the 973 National Key Basic Research Program in China (2015CB158300); the Shanghai Rising-star Program (18QA1401600).
Most land plants have evolved a mutualistic symbiosis with arbuscular mycorrhiza (AM)fungi that improve nutrient acquisition from the soil.In return,up to 20% of host plant photosynthate is transferred to the mycorrhi...
关键词：MYCORRHIZAL SYMBIOSIS lipid transfer TRANSCRIPTION factor AW box 
Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons被引量：4
《Translational Neurodegeneration》2018年第1期307-321,共15页Kangmu Ma Xiaobei Deng Xiaohuan Xia Zhaohuan Fan Xinrui Qi Yongxiang Wang Yuju Li Yizhao Ma Qiang Chen Hui Peng Jianqing Ding Chunhong Li Yunlong Huang Changhai Tian Jialin C.Zheng 
This work was supported in part by research grants from the National Basic Research Program of China(973 ProgramGrant No.2014CB965001 to JZ);Innovative Research Groups of the National Natural Science Foundation of China(#81221001 to JZ);Joint Research Fund for Overseas Chinese,Hong Kong and Macao Young Scientists of the National Natural Science Foundation of China(#81329002 to JZ);the National Institutes of Health:2R56NS041858-15A1(JZ),1R01NS097195-01(JZ),and R03 NS094071-01(YH);the State of Nebraska,DHHS-LB606 Stem Cell 2009-10 to JZ.
Background:Cell replacement therapy has been envisioned as a promising treatment for neurodegenerative diseases.Due to the ethical concerns of ESCs-derived neural progenitor cells(NPCs)and tumorigenic potential of iPS...
关键词：ASTROCYTES iNPCs REPROGRAMMING Transcription factor Neuronal lineage Cholinergic neurons Dopaminergic neurons Lhx8 Foxa2 Lmx1a 
Zinc finger transcription factor Sp7/Osterix acts on bone formation and regulates col10a1a expression in zebrafish被引量：5
《Science Bulletin》2017年第3期174-184,共11页Pengfei Niu Zhaomin Zhong Mingyong Wang Guodong Huang Shuhao Xu Yi HOU Yilin Yan Han Wang 
supported by the grants from National High Technology Research and Development Program of China (2011AA100402-2);the National Natural Science Foundation of China (NSFC) (31271356, 31030062, 81070455);National Basic Research Program of China (2012CB947600);the Jiangsu Distinguished Professorship Program (SR13400111);the Natural Science Foundation of Jiangsu Province (BK2012052);the Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions (YX13400214);the High-Level Innovative Team of Jiangsu Province;the ‘‘333” project of Jiangsu Province (BRA2015328)
Sp7/Osterix as a zinc finger transcription factor is expressed specifically in osteoblasts. Embryonic lethality of Sp7 knockout mice, however, has prevented from examining the functions of Sp7 in osteoblast and bone f...
关键词：Sp7/Osterix col10a1a Osteoblast Opercula TALEN Zebrafish 
Activating transcription factor 5 regulates lipid metabolism in adipocytes被引量：1
《Science Bulletin》2016年第23期1802-1809,共8页Jing-Hui Jiang Yue Zhao Liu-Ling Xiao Cui-Song Zhu Shu-Fen Li Xi Li 
supported by the National Key Basic Research Project (2013CB530601 to X. Li);the National Natural Science Foundation of China (81270954, 31571401 to X. Li)
Activating transcription factor 5(ATF5) is a member of the activating transcription factor/cA MP response element binding protein(ATF/CREB) family, and is highly expressed in liver and adipose tissue. Previous reports...
关键词：Activating tra scription factor 5 ADIPOCYTES Lipid metabolism. 
Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1被引量：5
《Acta Pharmacologica Sinica》2015年第10期1228-1236,共9页Zhan-ping LU Ze-lin XIAO Zhe YANG Jiong LI Guo-xing FENG Fu-quan CHEN Ying-hui LI Jin-yan FENG Yu-en GAO Li-hong YE Xiao-dong ZHANG 
Acknowledgements This work was supported by grants from the National Basic Research Program of China （973 Program, No 2015CB553703, 2015CB553905）, the National Natural Science Foundation of China （No 81272218, 81372186） and the Project of Prevention and Treatment of Key Infectious Diseases （No 2014ZX0002002005）.
Aim： Sphingosine kinase 1 （SPHK1） is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. As an oncogenic kinase, SPHK1 is as...
关键词：hepatitis B virus X protein hepatocellular carcinoma HepG2 ceils tumor xenograft model sphingosine kinase 1 transcription factor AP2α ceil proliferation 
The functional analysis of OsTDF1 reveals a conserved genetic pathway for tapetal development between rice and Arabidopsis被引量：19
《Science Bulletin》2015年第12期1073-1082,I0002,共11页Ci-Feng Cai Jun Zhu Yue Lou Zong-Li Guo Shuang-Xi Xiong Ke Wang Zhong-Nan Yang 
This work was supported by the grants from the Ministry of Science and Technology of China （2013CB945100）, the National Natural Science Foundation of China （31100227）.
During anther development, the tapetum pro- vides materials and nutrients for pollen development. In Arabidopsis, several transcription factors have been iden- tified to form a genetic pathway （DYT1-TDF1-AMS- MS188-...
关键词：Oryza sativa Transcription factor TAPETUM OsTDF1 
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