Objective To investigate the effects of bone morphogenetic protein-7(BMP7)on insulin signaling transduction in C2C12 myotubes and Hep G2 hepatocytes,and to study the underlying mechanisms preliminarily.Methods The C2C...
Objective To investigate the differential gene expression profile of the lung tissues in experimental silicosis rats and to screen for and identify the key signal transduction pathways in pulmonary silicotic fibrosis....
Objective To explore the influence of fluorine on mRNA and protein expression of the insulin-like growth factor-1 (IGF-1) and its receptor of rat osteoblasts.Methods Osteoblasts were isolated from rat bone by enzyme d...
Objective To observe the cell proliferation and the protein expression of STAT1,phosphorylation of STAT1(p-STAT1),STAT3,p-STAT3and transforming growth factor β1(TGF-β1) in human glomerulur
Objective To observe the effect of signal transduction pathway of NF-κB on tubular cell apoptosis in ischemia-reperfusion induced acute kidney injury(AKI)in mice.Methods Eighteen C57B/6 mice
Objective To study the transduction efficiency of expressing human neprilysin by using lentiviral(Lenti-NEP) in mouse embryonic neural stem cells(NSC) in vitro. Methods Primary NSC were harvested from C57BL/6J pregnan...
Objective To study the molecular mechanisms of Curcuma Wenyujin extract-mediated inhibitory effects on human esophageal carcinoma cells. Methods The Curcuma Wenyujin extract was obtained by supercritical carbon dioxid...
2010229 Expression and significance of phosphtidylinositol 3-kinase/protein kinase B signal transduction pathway in severe acute pancrceatitis-associated lung injury. KANG Xin(康新),et al. Dept Emerg Med,Zhongshan Hos...
To study on the effect of low dose irradiation (LDI) on expression of membrane molecules of T lymphocytes in cord blood.Methods Freshly isolated lymphocytes from cord blood were irradiated with 62mGy gamma-ray. At d...