TRAUMA

作品数：933被引量：1560H指数：18
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相关机构：浙江大学医学院附属第二医院西安外国语大学中国人民解放军总医院北京积水潭医院更多>>
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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury
《Neural Regeneration Research》2025年第11期3317-3329,共13页Jennifer M.Colón-Mercado Aranza I.Torrado-Tapias Iris K.Salgado Jose M.Santiago Samuel E.Ocasio Rivera Dina P.Bracho-Rincon Luis H.Pagan Rivera Jorge D.Miranda 
supported by COBRE(P30GM149367);the Puerto Rico Science&Technology Trust(2022-00125);MBRS-RISE Program(R25 GM061838);SC1GM144032 program(all to JDM)。
In addition to the loss of motor function,~60% of patients develop pain after spinal cord injury.The cellular-molecular mechanisms are not well understood,but the data suggests that plasticity within the rostral,epice...
关键词：ALLODYNIA central neuropathic pain EAAT-1/GLAST EAAT-2/GLT-1 glutamate transporters selective estrogen receptor modulator sexual dimorphism spinal cord injury TRAUMA 
Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury被引量：3
《Neural Regeneration Research》2024年第1期35-42,共8页Rongrong Wang Jinzhu Bai 
supported by Key Project of China Rehabilitation Research Center,Nos.2022ZX-05,2018ZX-08(both to JB)。
Traumatic spinal cord injury is a devastating disorder chara cterized by sensory,motor,and autonomic dysfunction that seve rely compromises an individual's ability to perform activities of daily living.These adve rse ...
关键词：blood-spinal cord barrier drug therapy MICROCIRCULATION microvascular blood flow NEUROPROTECTION pharmacological intervention PHARMACOTHERAPY spinal cord injury TRAUMA 
Ketamine,a trauma analgesic with sex-specific immunomodulatory function
《Neural Regeneration Research》2023年第6期1263-1264,共2页Haley F.Spencer Rina Y.Berman Martin Boese Kwang H.Choi 
Ketamine,a multimodal dissociative anesthetic,produces powerful analgesia at subanesthetic doses in traumatically injured patients.As ketamine does not induce respiratory depression or hemodynamic instability,the Comm...
关键词：doses ACUTE 
Functions and mechanisms of cytosolic phospholipase A_(2)in central nervous system trauma被引量：2
《Neural Regeneration Research》2023年第2期258-266,共9页Hao-Jie Zhang Yi-Tuo Chen Xin-Li Hu Wan-Ta Cai Xiang-Yang Wang Wen-Fei Ni Kai-Liang Zhou 
supported by the National Natural Science Foundation of China,No.82072192(to KLZ);Public Welfare Technology Research Project of Zhejiang Province,No.LGF20H150003(to KLZ);the Natural Science Foundation of Zhejiang Province,Nos.LY17H060009 and Y21H060050(both to WFN);Wenzhou Science and Technology Bureau Foundation,No.Y20210438(to KLZ)。
Central nervous system(CNS)trauma,including traumatic brain injury and spinal cord injury,has a high rate of disability and mortality,and effective treatment is currently lacking.Previous studies have revealed that ne...
关键词：autophagy cytosolic phospholipase A_(2) drugs lysosome membrane permeability mitogen-activated protein kinase NEUROINFLAMMATION spinal cord injury traumatic brain injury 
Robust temporal changes of cellular senescence and proliferation after sciatic nerve injury被引量：2
《Neural Regeneration Research》2022年第7期1588-1595,共8页Yin-Ying Shen Rui-Rui Zhang Qian-Yan Liu Shi-Ying Li Sheng Yi 
supported by the National Natural Science Foundation of China,No.31970968(to SYL);Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
Cellular senescence and proliferation are essential for wound healing and tissue remodeling.However,senescence-proliferation cell fate after peripheral nerve injury has not been clearly revealed.Here,post-injury gene ...
关键词：bioinformatic analysis cellular senescence dorsal root ganglia P16 peripheral nerve regeneration peripheral nerve trauma PROLIFERATION rat sciatic nerves sciatic nerve crush β-galactosidase activities 
Can lithium enhance the extent of axon regeneration and neurological recovery following peripheral nerve trauma?被引量：2
《Neural Regeneration Research》2022年第5期948-952,共5页Damien P.Kuffler 
The clinical"gold standard"technique for attempting to restore function to nerves with a gap is to bridge the gap with sensory autografts.However,autografts induce good to excellent recovery only across short nerve ga...
关键词：ANASTOMOSIS axon regeneration LITHIUM nerve crush nerve gaps nerve repair nerve trauma neurological recovery Schwann cells 
Chitin scaffold combined with autologous small nerve repairs sciatic nerve defects被引量：3
《Neural Regeneration Research》2022年第5期1106-1114,共9页Bo Wang Chang-Feng Lu Zhong-Yang Liu Shuai Han Pi Wei Dian-Ying Zhang Yu-Hui Kou Bao-Guo Jiang 
supported by the National Natural Science Foundation of China,Nos.31571236(to YHK),81971177(to BGJ);Key Laboratory of Trauma and Neural Regeneration(Peking University)of the Ministry of Education of China,No.BMU2020XY005-03(to BGJ);the National Key Research and Development Program of China,No.2016YFC1101604(to DYZ);the Ministry of Education Innovation Program of China,No.IRT_16R01(to BGJ);China Postdoctoral Science Foundation-Funded Project,No.2019M664007(to ZYL)。
Although autologous nerve transplantation is the gold standard for treating peripheral nerve defects,it has many clinical limitations.As an alternative,various tissue-engineered nerve grafts have been developed to sub...
关键词：autologous small nerve chitin scaffold nerve defect nervous system peripheral nerve injury peripheral nerve regeneration sciatic nerve TRAUMA 
Mesenchymal stem cell treatment for peripheral nerve injury:a narrative review被引量：7
《Neural Regeneration Research》2021年第11期2170-2176,共7页Rui-Cheng Zhang Wen-Qi Du Jing-Yuan Zhang Shao-Xia Yu Fang-Zhi Lu Hong-Mei Ding Yan-Bo Cheng Chao Ren De-Qin Geng 
funded by Clinical Medicine Key Project from the Social Development and Collaborative Innovation Plans in Xuzhou City of China,No.KC14SX016(to DQG).
Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life.The peripheral nervous system has an inherent capability to regenerate axons.However,peripheral nerve regeneration fol...
关键词：axonal regeneration EXOSOMES genetic engineering mesenchymal stem cells neural conduit peripheral nerve peripheral nerve injury peripheral nerve regeneration Schwann cells sudden trauma 
Role of circular RNA expression in the pathological progression after spinal cord injury
《Neural Regeneration Research》2021年第10期2048-2055,共8页Wen-Zhao Wang Jun Li Lei Liu Zheng-Dong Zhang Ming-Xin Li Qin Li Hui-Xu Ma Hai Yang Xiao-Ling Hou 
This study was supported by the National Natural Science Foundation of China,No.81874002(to LL);the Science and Technology Support Project of Sichuan Province of China,Nos.2018SZ0159(to LL),2018SZ0246(to XLH);the Innovation and Entrepreneurship Project of Sichuan Technology Gallery of China,Nos.2019JDRC0100(to JL),2020JDRC0054(to WZW);the National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University,China,Nos.Y2018B22(to LL),Z20192013(to JL);West China Hospital Postdoctoral Research and Development Fund,No.2019HXBH068(to JL)。
Differential expression of non-coding RNA after traumatic spinal cord injury(TSCI)is closely related to the pathophysiological process.The purposes of this study were to systematically profile and characterize express...
关键词：BIOINFORMATICS circRNA/miRNA/mRNA network circular RNA gene KLF4 miR-135b-5p spinal cord injury TRAUMA 
Glutathione precursors shield the brain from trauma
《Neural Regeneration Research》2019年第10期1701-1702,共2页Lilia Koza Daniel A. Linseman 
In the United States, approximately one-third of all injury-related deaths are due to traumatic brain injury (TBI). Anyone is at risk for TBI;however, the risk is higher for athletes in contact sports, military person...
关键词：In the UNITED STATES approximately one-third reactive nitrogen species 
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