supported by the Key Projects of Medical Science and Technology of Henan Province,No.SBGJ202002099(to JY)。
Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulat...
supported by JSPS KAKENHI Grant Number JP22K11823 to AH and JP22J01508 to KW。
Melatonin(N-acetyl-5-methoxytryptamine)is known as the hormone of darkness because it is synthesized at night and involved in regulating the circadian clock.The hormone is primarily synthesized by the vertebrate pinea...
supported by the National Natural Science Foundation of China (No.82071187,81870821,81501135,and 81471215);the National Key Research and Development Program of China (No.2021YFC2500100,2021YFC2500103);the Beijing Youth Talent Team Support Program (China) (No.2018000021223TD08);Science and Technology Program of Guangzhou (China) (No.202201020343).
CSF1R-microglial encephalopathy(CME)is a rare dementia with rapid development of cognitive impairment.The main clinical features of CME are progressive cognitive impairment,motor dysfunction,and neuropsychiatric sympt...
supported by the National Natural Science Foundation of China(No.51904036);the Hunan Provincial Key Research and Development Program,China(No.2023GK2049);Changsha Municipal Natural Science Foundation,China(Nos.kq2402016,kq2402014);the Postgraduate Scientific Research Innovation Project of Hunan Province,China(No.CX20240772);the Sichuan Science and Technology Program,China(No.2024NSFSC0151)。
The microstructure and mechanical properties of Mg−4.5Al−2.5Zn−0.3Mn−0.2Ca(wt.%,designated as AZ42)alloys in extruded(at extrusion ratios of 28,20 and 11.5)and peak-aged states were investigated,by using optical micro...
supported by grants from the Science and Technology Foundation of Chongqing,China (No.cstc2021jcyj-bshX0056);the Key Grant from the National Clinical Research Center for Child Health and Disorders (China) (No.NCRCCHD-2021-KP-01);the National Natural Science Foundation of China (No.81974030);the National Key Clinical Specialty (China).
Aging is an independent risk factor for cardiovascular diseases.Cardiac diastolic dysfunction(CDD),ultimately leading to heart failure with preserved ejection fraction(HFpEF),is prevalent among older individuals.Altho...