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Multidimensional Role of Amino Acid Metabolism in Immune Regulation:From Molecular Mechanisms to Therapeutic Strategies: 《Chemical Research in Chinese Universities》2025年第1期1-14,共14页QIN Changjuan YANG Guanqing WEI Qi XIN Hua DING Jianxun CHEN Xuesi; supported by the National Natural Science Foundation of China(Nos.U23A20591,52273158,and 52203200);the Science and Technology Development Program of Jilin Province,China(Nos.20240101002JJ,20240404010ZP,and YDZJ202402077CXJD);the Youth Talents Promotion Project of Jilin Province,China(No.Y2023066).; Immune cells are essential components of the human immune system,playing a critical role in maintaining human health and defending against diseases.Changes in nutritional metabolism influence the activation,proliferat...; 关键词：Amino acid METABOLISM Dendritic cell T cell IMMUNOMODULATION

Molecular Insights into Distinct Membrane-insertion Behaviors and Mechanisms of 20 Amino Acids:an All-atom MD Simulation Study: 《Chemical Research in Chinese Universities》2023年第5期829-839,共11页TU Wenqiang DONG Xuewei OU Luping ZHANG Xinke YUAN Bing YANG Kai; This work was supported by the Open Research Fund of Songshan Lake Materials Laboratory,China(No.2021SLABFK10);the National Natural Science Foundation of China(Nos.12274307,32230063,21774092 and 22303060);the Natural Science Foundation of Guangdong Province,China(No.2023A1515011610);the Open Research Fund of State Key Laboratory of Surface Physics of Fudan University,China(No.KF2023_03).; Interfacial interactions of proteins with cell membranes play important roles in fundamental physiological processes of cells.The binding of proteins to membranes involves interactions between amino acids and membrane...; 关键词：Amino acid-membrane interaction Membrane insertion capability Insertion depth and angle Molecular dynamic simulation

Contemporary Approaches toα,β-Dehydroamino Acid Chemical Modifications: 《Chemical Research in Chinese Universities》2021年第5期1044-1054,共11页ZHANG Mengqian HE Peiyang LI Yanmei; This work was supported by the National Key R&D Program of China(Nos.2018YFA0507600,2019YFA0904200);the National Natural Science Foundation of China(No.92053108).; As one of the most common unnatural amino acids(uAAs),α,β-dehydroamino acids(α,β-dhAAs)can be found in various ribosomally synthesized and post-translationally modified peptides(RiPPs)and other naturally occurring...; 关键词：TRANSLATIONAL CONTINUE ACIDS

Chemical Synthesis of Proteins Containing 300 Amino Acids被引量：4: 《Chemical Research in Chinese Universities》2020年第5期733-747,共15页ZHANG Baochang LI Yulei SHI Weiwei WANG Tongyue ZHANG Feng LIU Lei; Supported by the National Key R&D Program of China(No.2017YFA0505200);the National Natural Science Foundation of China(Nos.21532004,91753205,81621002).; Chemical synthesis of proteins containing up to 300 amino acids may cover 30%—50%of all the proteins encountered in biomedical studies and may provide an alternate approach to the usually used recombinant expression ...; 关键词：Chemical protein synthesis Solid-phase synthesis PEPTIDE LIGATION 300 amino acid

Baeyer-Villiger Oxidation of Cyclic Ketones Catalyzed by Amino Acid Ionic Liquids被引量：2: 《Chemical Research in Chinese Universities》2020年第5期865-869,共5页YU Fengli CHI Yujie GAO Chong CHEN Ruirui XIE Congxia YU Shitao; Supported by the National Natural Science Foundation of China(No.21878166);the Taishan Scholar Project of Shandong Province,China(No.ts201511033);the Emphasis Development Plan of Shandong Province,China(Nos.2017GGX70102,2017GGX40107);the Open Project of the Chemistry Department in Qingdao University of Science and Technology of China(No.QUSTHX201811).; A series of amino-acid-based ionic liquids was synthesized via one-step protonation of the corresponding L-amiiio acid by utilizing an array of proton sources.The catalytic activity of the amino-acid-based ionic liqui...; 关键词：Amino acid ionic liquid Baeyer-Villiger oxidation Cyclic ketone LACTONE

Aerobic Alcohol Ammoxidation Catalyzed by Copper（I）/Amino Acid： a Scalable Protocol to Nitriles被引量：1: 《Chemical Research in Chinese Universities》2016年第4期586-593,共8页ZHANG Guofu ZHANG Guihua LEI Jie LI Shasha XU Shengjun DING Chengrong SHAN Shang; Supported by the National Natural Science Foundation of China（No.20702051） and the Natural Science Foundation of Zhejiang Province, China（No.LY 13B020017）.; A facile, practical and scalable catalyst system for alcohols ammoxidation into nitriles was developed using amino acid as ligand, oxygen as terminal oxidant and copper iodide（CuI） as catalyst. The catalyst system s...; 关键词：ALCOHOL Amino acid NITRILE Copper iodide Scale up

Rapid Determination of Amino Acids in Ginseng by High Performance Liquid Chromatography and Chemometric Resolution被引量：2: 《Chemical Research in Chinese Universities》2014年第4期578-581,共4页HAN Jing WU Xi CAI Wensheng SHAO Xueguang; Supported by the National Natural Science Foundation of China（No.21175074）.; Ginseng is one of the most important traditional Chinese medicines and functional foods.A method for the fast determination of amino acids in ginseng samples using high performance liquid chromatography（HPLC） was de...; 关键词：High performance liquid chromatography（HPLC） CHEMOMETRICS Amino acid GINSENG Immune algorithm

Theoretical Studies on Complexes of Calcium Ion with Amino Acids被引量：1: 《Chemical Research in Chinese Universities》2014年第1期125-129,共5页QIN Penghua LU Wencai QIN Wei ZHANG Wei XIE Hui; Supported by the National Natural Science Foundation of China（No. 21273122）.; The complexes formed by calcium ion and 12 common amino acids were investigated systematically in the gas phase at the level of MP2/6-311＋＋G（d,p）//MP2/6-3 1G（d,p）.The results show that the salt-bridge structure ...; 关键词：Amino acid Calcium ion complex MP2 calculation

Synthesis, Crystal Structures and Catalysis of Dinuclear Cd(Ⅱ) Complexes Bridged by Unusual (N,O,O′)-Coordinated α-Amino Acids: 《Chemical Research in Chinese Universities》2012年第1期73-78,共6页DENG Dong-sheng1,2, WANG Li1, PEI Ya-mei1, FENG Lu2 and LIU Chang-lin1 1. Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, School of Chemistry, Central China Normal University, Wuhan 430079, P. R. China 2. College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, P. R. China; Supported by the National Natural Science Foundation of China(No.21001047);the Self-determined Research Funds of Central China Normal University from the Colleges’ Basic Research and Operation of Ministry of Education, China(No. CCNU10A01010); Four dinuclear amino acid cadmium（II） complexes [Cd2（tren）2（dl-alaninato）]（ClO4）3·H2O（I）, [Cd2（tren）2· （l-alaninato）]（ClO4）3·H2O（II）, [Cd2（tren）2（dl-phenylalaninato）]（ClO4）3（III） and [Cd2...; 关键词：Dinuclear cadmium（II） complex Amino acid Aldol reaction

Syntheses, Structures, and Properties of Five Coordination Polymers Involving Phthalic Acid: 《Chemical Research in Chinese Universities》2011年第5期724-729,共6页WU Li-li HE Rong WEI Zhen SONG Hui-hua; Supported by the National Natural Science Foundation of China(Nos.20601007, 20773034);the Natural Science Foundation of Hebei Province, China (No.B2008000143);the Natural Science Foundation of Hebei Education Department, China(No. ZH2006002);the Doctoral Foundation of Hebei Normal University, China (No.103261); Five new coordination polymers Cu（phen）（H2O）（phth）·CH3OH（1）, [Cu（2,2′-bipy）（H2O）]（phth）·3.5H2O（2）, Zn（phen）（phth）（H2O）·1.125H2O（3） and [M（4,4′-bipy）（H2O）2]（phth）·2H2O[M=Zn（4）, Mn...; 关键词：Crystal structure Amino acid derivative Phthalic acid Coordination polymer

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