Supported by The Guangdong Basic and Applied Basic Research Foundation,No.2023A1515011432;The Guangzhou Science and Technology Planning Project,No.2023A04J0627;and National Natural Science Foundation of China,No.82004256.
BACKGROUND Early diagnosis and therapeutic interventions can greatly enhance the developmental trajectory of children with autism spectrum disorder(ASD).However,the etiology of ASD is not completely understood.The pre...
BACKGROUND Angioedema is a disorder characterized by edema of the face,lips,tongue,and extremities due to increased vascular permeability.Angioedema of the tongue usually occurs bilaterally,and the incidence of unilat...
supported by the Fujian Provincial Health Technology Project of China,No.2018-CX-16;Fujian Provincial Hospital Flint Fund Project,No.2020HSJJ17(both to SRL).
Bradykinin(BK)is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective effects.We previously showed that BK postconditioning strongly protects rat hippocam...
the Arizona Biomedical Research Commission(ABRC)young investigator award;the Fred Hutchinson Cancer Research Center(0000917241);Tulane University Startup fund。
The critical roles of oxygen homeostasis in metabolism are indisputable and hypoxic responses are correlated with the pathogenesis of gastrointestinal, pulmonary, renal diseases and cancers. Evaluating tissue hypoxia ...
Circulating peptide is a potential source of biomarkers for cancer detection.However,the existence of large molecular weight proteins in plasma have a disastrous effect on circulating peptides isolating and detecting....
This placebo-controlled, double-blind, cross-over intervention with twelve normotensive healthy volunteers tested the effects of milk products containing either 5 or 50 mg of ACE1-inhibitory lactotripeptides (isolecin...
supported by Project of Natural Science Foundation of Hebei Province,No.H2014406047;Key Program of Science and Technology of Hebei Higher Education,No.ZD20131001~~
Objective: To observe the changes in numbers and degranulation status of local mast cells (MCs) of the complementary acupionts, as well as the concentrations of serum histamine and bradykinin after acupuncture at ...
AIM To study activation of extracellular signal-regulated kinase-1/2(ERK1/2) and pro-matrix metalloproteinases(pro-MMPs) secretion from isolated primary human ciliary muscle(h-CM) cells in response to bradykinin(BK) a...
OBJECTIVE: Though the initial etiologies of arthritis are multifactorial, clinically, patients share the prime complaints of the disease, pain. Here the authors assessed the analgesic and anti-inflammatory effects of...
Supported by Grants from the Shandong Provincial Natural Science Foundation,China,No.ZR2009CL047 and No.ZR2011HM043;the Scientific Research Foundation for Returned Scholars(Ministry of Education of China,2011,43~(th));Shandong Province Higher Educational Science and Technology Program,No.J14LK15;Excellent Teachers International Training Cooperation Program of Shandong Province(for Yang XY and Qu MH)
AIM: To investigate the mechanism for bradykinin(BK) to stimulate intestinal secretomotor neurons and intestinal chloride secretion. METHODS: Muscle-stripped guinea pig ileal preparations were mounted in Ussing flux c...