This work was supported by the National Natural Science Foundation of China(51125014,51233003 and 21474077);the Ministry of Science and Technology of China(2011CB606202).
Camptothecin(CPT)-based drugs always undergo the reversible,pH-dependent lactone ring-opening reaction,yielding the inactive but toxic carboxylate form.Self-assembly strategy provides an effective route for preserving...
This work was supported by the Spain’s Ministerio de Economı´a y Competitividad[projects MAT2008-06887-C03-01,MAT2010-15310,MAT2013-41723-R,MAT2013-42473-R,VA313U14 and VA244U13].X.P.acknowledges grant BES-2009-027524 from the Spain’s Ministerio de Economı´a y Competitividad.
The integration of implants or medical devices into the body tissues requires of good cell–material interactions.However,most polymeric materials used for these applications lack on biological cues,which enhanced mid...
This work was financed by Portuguese funds through FCT-Fundac¸a˜o para a Cieˆncia e a Tecnologia in the framework of project UID/BIM/04293/2013.L.R.P.thanks FCT for her PhD grant(SFRH/BD/46015/2008).
Biomaterial-based strategies to restore connectivity after lesion at the spinal cord are focused on bridging the lesion and providing an favourable substrate and a path for axonal re-growth.Following spinal cord injur...
This work was supported by the Natural Science Foundation of China(Grant No.51303196 and U1432114);Ningbo Natural Science Foundation of China(Grant No.2013A610092);the Key Breakthrough Program of the Chinese Academy of Sciences(KGZD-EW-T06);Hundred Talents Program of Chinese Academy of Sciences(A.G.U.,2010-735).
Neuropeptide Y(NPY)was first identified from porcine brain in 1982,and plays its biological functions in humans through NPY receptors(Y1,Y2,Y4 and Y5).NPY receptors are known to mediate various physiological functions...
This work was financially supported by the National Natural Science Foundation of China(Nos.51303174,51273196,51203153,51233004,51390484,and 51321062);the Scientific Development Program of Jilin Province(Nos.20140520050JH and 20140309005GX);the Science and Technology Planning Project of Changchun City(No.14KG045).
The osteochondral defects caused by vigorous trauma or physical disease are difficult to be managed.Tissue engineering provides a possible option to regenerate the damaged osteochondral tissues.For osteochondral recon...