COLORECTAL

作品数：1242被引量：5539H指数：26
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相关机构：江苏省人民医院浙江省肿瘤医院复旦大学附属肿瘤医院上海健康医学院更多>>
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Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy
《Genes & Diseases》2025年第2期304-318,共15页Wei Qiao Shuxin Li Linna Luo Meiling Chen Xiaobin Zheng Jiacong Ye Zhaohui Liang Qiaoli Wang Ting Hu Ling Zhou Jing Wang Xiaosong Ge Guokai Feng Fang Hu Rongbin Liu Jianjun Li Jie Yang 
supported by grants from the National Natural Science Foundation of China (No.82373174,82002466,82202907).
Photodynamic therapy is an"old"strategy for cancer therapy featuring clinical safety and rapid working,but suitable photosensitizers for colorectal cancer therapy remain lacking.This study synthesized a novel photosen...
关键词：Anti-tumorimmunity Ce6-GFFY Colorectal cancer Novel photosensitizer Photodynamic therapy 
Construction of a risk prediction model for postoperative cognitive dysfunction in colorectal cancer patients
《World Journal of Gastrointestinal Surgery》2025年第4期221-232,共12页Zhen-Ping Zheng Yong-Guo Zhang Ming-Bo Long Kui-Quan Ji Jin-Yan Peng Kai He 
Supported by the Research Fund of Qiannan Medical College for Nationalities,No.Qnyz202222.
BACKGROUND Colorectal cancer(CRC)is one of the most prevalent and lethal malignant tumors worldwide.Currently,surgical intervention was the primary treatment modality for CRC.However,increasing studies have revealed t...
关键词：Colorectal cancer POSTOPERATIVE Cognitive dysfunction ANESTHESIA Risk prediction model DEXMEDETOMIDINE Preventive value 
A surgical orthotopic xenograft approach with immune response for colorectal cancer research
《Animal Models and Experimental Medicine》2025年第3期558-567,共10页Xiaoying Hou Xiaoxuan Li Qian Fang Yufei Deng Haiping Wang Binlian Sun Chengliang Zhang Hongzhi Du Yuchen Liu 
Research Fund of Jianghan University,Grant/Award Number:2021jczx-002;Natural Science Foundation of Hubei Province,Grant/Award Number:2024AFB941 and 2024AFD241;Wuhan Science and Technology Project,Grant/Award Number:2023010201020448;National Natural Science Foundation of China,Grant/Award Number:82204416。
The high morbidity and mortality of colorectal cancer(CRC)is a major challenge in clinical practice.Although a series of alternative research models of CRC have been developed,appropriate orthotopic animal models that...
关键词：animal model colorectal cancer orthotopic tumor model tumor immunology 
Important role of lymphovascular and perineural invasion in prognosis of colorectal cancer patients with N1c disease
《World Journal of Gastroenterology》2025年第5期57-67,共11页Zhi-Gang Sun Shao-Xuan Chen Bai-Long Sun Da-Kui Zhang Hong-Liang Sun Huang Chen Yu-Wan Hu Tong-Yin Zhang Zi-Han Han Wen-Xiao Wu Zhi-Yong Hou Li Yao Jian-Zheng Jie 
Supported by the National High Level Hospital Clinical Research Funding,No.2023-NHLHCRF-BQ-32 and No.2023-NHLHCRFYYPPLC-ZR-13;the Elite Medical Professionals Project of China-Japan Friendship Hospital,No.ZRJY2024-GG01.
BACKGROUND Lymphovascular invasion(LVI)and perineural invasion(PNI)are associated with decreased survival in colorectal cancer(CRC),but its significance in N1c stage remains to be clearly defined.AIM We retrospectivel...
关键词：Colorectal cancer N1c Lymphovascular invasion Perineural invasion PROGNOSIS 
Discovery of a novel viroid-like circular RNA in colorectal cancer
《Cancer Communications》2025年第1期46-50,共5页Meini Wu Wenliang Li Ningzhu Hu Changning Liu Jianfang Li Yanhan Li Ning Xu Jiandong Shi Jing Sun Jing Li Yunzhang Hu 
supported by grants from the National Natural Science Foundation of China(No.31500748);the CAMS Innovation Fund for Medical Sciences(No.2017-I2M-3-022).
Viroids,the smallest known infectious agents,were initially discovered in plants[1],and have caused significant agricultural diseases[2–4].Recently,viroids have been identified in fungi[5–7]and bacteria[8],but none ...
关键词：COLORECTAL CANCER CIRCULAR 
Construction of a nomogram prediction model for early postoperative stoma complications of colorectal cancer
《World Journal of Gastrointestinal Surgery》2025年第1期165-174,共10页Ming-Qin Ba Wen-Lin Zheng Yu-Ling Zhang Lin-Lin Zhang Jing-Jing Chen Jie Ma Jia-Li Huang 
BACKGROUND Postoperative enterostomy is increasing in patients with colorectal cancer,but there is a lack of a model that can predict the probability of early complications.AIM To explore the factors influencing early...
关键词：COLORECTAL POSTOPERATIVE STOMA COMPLICATIONS NOMOGRAM 
Interplay and therapeutic implications of colorectal cancer stem cells,tumor microenvironment,and gut microbiota
《World Journal of Stem Cells》2024年第12期1110-1114,共5页Hui Zhang Bo-Tao Xu Di-Ping Luo Tie-Fei He 
This article discusses the interplay between colorectal cancer(CRC)stem cells,tumor microenvironment(TME),and gut microbiota,emphasizing their dynamic roles in cancer progression and treatment resistance.It highlights...
关键词：Colorectal cancer Stem cells Tumor microenvironment Gut microbiota Treatment resistance Therapeutic strategies Personalized medicine Cancer ecosystem Research advancements 
The Role of High Expression of BECN1 and CD68 in Prognostic Evaluation for Colorectal Cancer Patients
《Proceedings of Anticancer Research》2024年第6期239-250,共12页Yan Zhang Wenjiong Sheng Yuhui Han Xiuxin Liu Yanchao Ma 
National Natural Science Foundation of China Youth Fund Project(82203543);Shandong Provincial Natural Science Foundation Youth Fund Project(ZR2022QH267);Shandong Provincial Innovation Development Joint Fund Project(ZR2023LZL008);Binzhou Medical University Research Start-up Fund Project(50012304458);Shandong Province Medical and Health Science and Technology Project(202309030619)。
Objective:To explore the changes in the expression of autophagy-related protein BECN1 and tumor-associated macrophage marker CD68 in colorectal cancer and investigate their association with clinicopathological feature...
关键词：Colorectal cancer AUTOPHAGY BECN1 Tumor-associated macrophages CD68 
Prognostic value of combined systemic inflammation response index and prognostic nutritional index in colorectal cancer patients
《World Journal of Gastrointestinal Surgery》2024年第12期3794-3805,共12页Ke-Jin Li Zi-Yi Zhang Subinur Sulayman Yin Shu Kuan Wang Saibihutula Ababaike Xiang-Yue Zeng Ze-Liang Zhao 
Supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region,No.2022D01C297.
BACKGROUND The prognosis of colorectal cancer(CRC)patients is notably influenced by both inflammation and nutritional status.The prognostic nutritional index(PNI)and systemic inflammatory response index(SIRI)have been...
关键词：Colorectal cancer Prognostic nutritional index Systemic inflammatory response index PROGNOSIS 
Assessing a complex patient with both colorectal cancer and diverticulitis of the sigmoid colon: A case report and literature review
《Laparoscopic, Endoscopic and Robotic Surgery》2024年第4期181-185,共5页Luis A.Hernandez-Flores Daniel Aillaud-De-Uriarte Fabiola Perez-Baca Arion Yu Diego Marines-Copado 
Diverticular disease,including diverticulitis,is a common disease;it accounts for more than 165,000 annual admissions in the United States,1 with an incidence of 188/100,000 person-years,2 being the most common gastro...
关键词：COLON diagnosis COLORECTAL 
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