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作品数：277被引量：66H指数：4
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相关机构：广州六福营销策划有限公司江苏省常熟市实验小学山西师范大学清华大学更多>>
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Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome被引量：1
《Cell Research》2019年第4期330-333,共4页Tonghui Yao Wei Jing Zhiguo Hu Ming Tan Mi Cao Qianmin Wang Yan Li Guiyong Yuan Ming Lei Jing Huang 
the National Key R&D Program of China(2016YFA0501803 and 2017YFA0504504);the National Natural Science Foundation of China(31570766 and U1632130);the Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(2017YZ004);the SHIPM-sigma fund(BJ1-7009-18-1303 and JY201805)from Shanghai Institute of Precision Medicine,Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,and Chinese Academy of Sciences Facility-based Open Research Program.
Dear Editor,Histone marks deposited by post-translational modifications(PTMs)frequently occur in interrelated combinational patterns to create a complex and precise control on the chromatin structure and function.1 On...
关键词：DEAR Editor complex and precise control TELOMERE SILENCING protein 
Transcriptome-wide reprogramming of N^6-methyladenosine modification by the mouse microbiome被引量：6
《Cell Research》2019年第2期167-170,共4页Xiaoyun Wang Yan Li Wenjun Chen Hailing Shi A.Murat Eren Aleksey Morozov Chuan He Guan-Zheng Luo Tao Pan 
National Institutes of Health (K01 DKI 11764 to XYW,RMI HGO08935 to TP);DoD/CDMRP (BC160450 to TP);the Natlonal Natural Science Foundation of China (31741033 and 91753129 to GZL).
Dear Editor, Microbiome affects many aspects of human health and disease and elicits a wide range of host responses including remarkable epigenetic changes such as DNA methylation,histone modification and non-coding R...
关键词：DEAR EDITOR MICROBIOME AFFECTS human health 
Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications被引量：4
《Cell Research》2019年第2期171-173,共3页Fan Yu Song Guo Te Li Jie Ran Wei Zhao Dengwen Li Min Liu Xiumin Yan Xiaoyong Yang Xueliang Zhu Jun Zhou 
grants from the National Key R&D Program of China (2017YFA0503500);the National Natural Science Foundation of Chma (31730050, 31701169,31741039,and 31471262).
Dear Editor Diabetes is a chronic metabolic disease that has become a major epidemic worldwide. High blood glucose is thought to be the primary cause of most devastating long-term complications of diabetes. In additio...
关键词：DEAR Editor Diabetes chronic metabolic disease EPIDEMIC WORLDWIDE 
Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome被引量：4
《Cell Research》2019年第2期174-176,共3页Jianan Li Zhen Liu Shisheng Huang Xiao Wang Guanglei Li Yuting Xu Wenxia Yu Shanshan Chen Yu Zhang Hanhui Ma Zunfu Ke Jia Chen Qiang Sun Xingxu Huang 
Dear Editor, Most disease-associated genomic mutations are base substitutions and approximately half of pathogenic human single nucleotide polymorphisms (SNPs)are related to C-to-T substitutions in the ClinVar databas...
关键词：DEAR Editor disease-associated GENOMIC MUTATIONS EFFICIENT BASE EDITING 
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