EPSTEIN-BARR_VIRUS

作品数:211被引量:791H指数:14
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相关作者:罗兵翁新宪顾焕华邓锡云曹亚更多>>
相关机构:青岛大学湖南医科大学福建省肿瘤医院昆明医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>
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Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein-Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma被引量:11
《Chinese Journal of Cancer》2017年第12期737-743,共7页Ji‑Jin Yao Guan‑Qun Zhou Ya‑Qin Wang Si‑Yang Wang Wang‑Jian Zhang Ya‑Nan Jin Fan Zhang Li Li Li‑Zhi Liu Zhi‑Bin Cheng Jun Ma Zhen‑Yu Qi 
supported by Grants from the National Natural Science Foundation of China(Nos.81372409,81402532);the Sun Yat-sen University Clinical Research 5010 Program(No.2012011)
Background: According to the 7 th edition of the American Joint Committee on Cancer(AJCC) staging system, over50% of patients with nasopharyngeal carcinoma(NPC) have N1 disease at initial diagnosis. However, patients ...
关键词:NASOPHARYNGEAL carcinoma LYMPH node VOLUME Epstein–Barr virus DNA Distant metastasis Prognostic model 
Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis被引量:3
《Chinese Journal of Cancer》2016年第3期100-108,共9页Ying Shi Song‑Ling Peng Li‑Fang Yang Xue Chen Yong‑Guang Tao Ya Cao 
supported by the National Basic Research Program of China[2011CB504300(Y.T.;Y.C.),2015CB553903(Y.T.)];the National High Technology Research and Development Program of China(863 Program)[2012AA02A501(Y.C.)];the National Natural Science Foundation of China[81,171,881 and81372427(Y.T.),81271763(S.L.),81,302,354(Y.S.)];the Hunan Natural Science Foundation of China[12JJ1013(Y.T.)]
Viral infections contribute to approximately 12%of cancers worldwide,with the vast majority occurring in developing countries and areas.Two DNA viruses,Epstein-Barr virus(EBV) and human papillomavirus(HPV),are associa...
关键词:EPSTEIN-BARR virus  Human papillomavirus  Co-infection  NASOPHARYNGEAL carcinoma  Cervical cancer Breast cancer  Prostate CANCER 
single nucleotide polymorphism in theEpstein-Barr virus genome is strongly associatedwith a high risk of nasopharyngeal carcinoma被引量:7
《Chinese Journal of Cancer》2015年第12期563-572,共10页
Background Epstein-Barr virus (EBV) commonly infects the general population and has been associated withnasopharyngeal carcinoma (NPC), which has a high incidence in certain regions.This study aimed to address how...
关键词:EPSTEIN-BARR virus  NASOPHARYNGEAL carcinoma  RPMS1  Association 
Epstein-Barr virus and the origin of Hodgkin lymphoma被引量:2
《Chinese Journal of Cancer》2014年第12期591-597,共7页Martina Vockerodt Fathima Zumla Cader Claire Shannon-Lowe Paul Murray 
Although Epstein-Barr virus(EBV)is present in the malignant Hodgkin/Reed-Sternberg(HRS)cells of a proportion of cases of classical Hodgkin lymphoma(c HL),how the virus contributes to the pathogenesis of this disease r...
关键词:EPSTEIN-BARR病毒 淋巴瘤 起源  恶性肿瘤 发病机制 辅助因子 EBV 
Epstein-Barr virus and Burkitt lymphoma被引量:16
《Chinese Journal of Cancer》2014年第12期609-619,共11页Martin Rowe Leah Fitzsimmons Andrew I Bell 
supported by a grant from the Cancer Research UK,London(Programme Award C5575/A15032)
In 1964,a new herpesvirus,Epstein-Barr virus(EBV),was discovered in cultured tumor cells derived from a Burkitt lymphoma(BL)biopsy taken from an African patient.This was a momentous event that reinvigorated research i...
关键词:EPSTEIN-BARR病毒 淋巴瘤 C-MYC基因 肿瘤细胞 发病机理 染色体易位 C-MYC 疱疹病毒 
Epstein-Barr virus and nasopharyngeal carcinoma被引量:32
《Chinese Journal of Cancer》2014年第12期581-590,共10页Lawrence S.Young Christopher W.Dawson 
supported by Cancer Research UK and the European Commission’s FP6 Life-Sciences-Health Programme(INCA Project:LSHC-CT-2005-018704)
Since its discovery 50 years ago,Epstein-Barr virus(EBV)has been linked to the development of cancers originating from both lymphoid and epithelial cells.Approximately 95%of the world’s population sustains an asympto...
关键词:EPSTEIN-BARR病毒 鼻咽癌 肿瘤细胞 上皮细胞 EB病毒 癌症治疗 细胞起源 世界人口 
Epstein-Barr virus at 50——future perspectives被引量:1
《Chinese Journal of Cancer》2014年第11期527-528,共2页Lawrence S.Young 
The special November and December issues of the Chinese Journal of Cancer celebrate the 50th anniversary of the discovery of Epstein-Barr virus(EBV) with a series of reviews covering the association of the virus with ...
关键词:EPSTEIN-BARR病毒 病毒感染 NPC 发病机制 EB病毒 临床医生 相互作用 环境因素 
Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma被引量:9
《Chinese Journal of Cancer》2014年第11期529-538,共10页Samantha Wei-Man Lun Siu-Tim Cheung Kwok-Wai Lo 
supported by funding from the Focus Investigation Scheme-A of The Chinese University of Hong Kong;the Research Grants Council of Hong Kong, GRF (471211, 470312), CRF (CUHK8/CRF/11R) and AoE NPC (AoE/M-06/08);the Theme-Based Research Scheme (T12-401/13-R)
Although the Epstein-Barr virus(EBV) has spread to all populations in the world, EBV-associated nasopharyngeal carcinoma(NPC) is prevalent only in South China and Southeast Asia. The role of EBV in the malignant trans...
关键词:肿瘤干细胞 EB病毒 鼻咽癌 潜伏膜蛋白1 上皮细胞 东南亚地区 三磷酸腺苷 EBV 
The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma被引量:13
《Chinese Journal of Cancer》2014年第11期556-568,共13页Maria Li Lung Arthur Kwok Leung Cheung Josephine Mun Yee Ko Hong Lok Lung Yue Cheng Wei Dai 
supported by the Research Grants Council Area of Excellence grant (AoE/M-06/08)
The interplay between host cell genetics and Epstein-Barr virus(EBV) infection contributes to the development of nasopharyngeal carcinoma(NPC). Understanding the host genetic and epigenetic alterations and the influen...
关键词:EB病毒 遗传因素 鼻咽癌 宿主 人类白细胞抗原 细胞遗传学 基因调控 细胞信号 
Polymorphisms of Epstein-Barr virus BHRF1 gene, a homologue of bcl-2被引量:7
《Chinese Journal of Cancer》2010年第12期1000-1005,共6页Yong-Zheng Jing Yun Wang Yu-Ping Jia Bing Luo 
National Natural Science Foundation of China (No30740068);Natural Science Foundation of Shandong Province, China(No Y2008C90)
Background and Objective: EBV BamHI fragment H rightward open reading frame 1 (BHRF1), the Epstein-Barr virus (EBV) early gene, is structurally and functionally homologous to the oncogene bcl-2 and may play an importa...
关键词:EB病毒 早期基因 同源基因 多态性 全国人民代表大会 基因突变 开放阅读框架 聚合酶链反应 
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