This study has been financially supported by the National Key R&D Program of China(2021YFA0805800 and 2020YFA0803202 to R.J.);the National Natural Science Foundation of China(31970538 to R.J.,32100703 to C.W.);Guangzhou Medical University Discipline Construction Funds(Basic Medicine)(JCXKJS2022A02 to R.J.);the 111 Project(D18010 to R.J.),the Local Innovative and Research Teams Project of Guangdong Perl River Talents Program(2017BT01S155 to R.J.);the Special Innovation Projects of Universities in Guangdong Province(2022KTSCX096 to C.W.);the grant of the State Key Laboratory of Respiratory Disease,Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease(GHMJLRID-Z-202106 to C.W.).
The innate immune system is the first line of host defense against the invading pathogens in multicellular organisms,which is the key to eliminating pathogen infections,mitigating pathogen-induced inflammation,and act...
supported by the National Key Research and Development Program of China(No.2022YFD1200300);by grants from the State Key Laboratory of Plant Genomics.
The fungal cell wall is the front-line in host-pathogen interactions,which is an essential dynamic structure maintaining cellular integrity and protecting the fungal cell from external aggressors,such as environmental...
supported by the National Natural Science Foundation of China,China(32000576);the Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0882).
Angiogenesis is a process in which newborn vessels sprout from preexisting blood vessels(Isogai et al.,2003;Geudens and Gerhardt,2011;Herbert and Stainier,2011;Chen et al.,2019,2021),and the dynamic changes of the cyt...
supported by the National Natural Science Foundation of China(31671336 and 31972958);the Start-Up Funds for High Level Talents of Qingdao Agricultural University(663-1120001);the First Class Grassland Science Discipline Program of Shandong Province,China。
Chloroplasts most likely originated from the endosymbiosis of cyanobacterial ancestors,entering the eukaryotic lineage about 1.0-1.5 billion years ago(Parfrey et al.,2011;Archibald,2015).Consequently,their biogenesis ...
supported by grants from the Guangdong Natural Science Funds for Distinguished Young Scholars (2021B1515020089);the National Natural Science Foundation of China (32030080);the Major Program of Guangdong Basic and Applied Research(2019B030302006)
In plants,lipid transfer proteins(LTPs)transport pollen wall constituents from the tapetum to the exine,a process essential for pollen wall development.However,the functional cooperation of different LTPs in pollen wa...
funded by grants from the National Institutes of Health (R01GM129157, R01HD095938, R01HD097268, and R01HL146664);by contracts from New York State Stem Cell Science (NYSTEM#C35583GG and C35584GG)。
Pluripotency is recognized as a spectrum of cellular states spanning the na?ve pluripotency established in the preimplantation blastocyst and its transition into primed pluripotency in the postimplantation epiblast ce...
supported by the National Natural Science Foundation of China(32070739,31771528,and 91754107);Zhejiang Provincial Natural Science Foundation of China(LR21C070001);the National Basic Research Program of China(2017YFA0503402)to C.Yi;Natural Science Foundation for Young Scientists of China(81800085);Natural Science Foundation of Hubei Province,China(ZRMS2020002147)to J.Tong;Zhejiang Key R&D Program of China(2019C02030)to L.Zhang。
Autophagy is a highly conserved degradation process in which intracellular components are engulfed into a double membrane structure,known as the autophagosomes,and then delivered to lysosomes/vacuoles for degradation(...
grants from the National Key R&D Program of China(2018YFA0903202);the China Postdoctoral Science Foundation(230210538)。
Embryogenesis is central to the life cycle of higher plants,which starts from division of the single-cell zygote and culminates in formation of the mature embryo with major cell precursors.Such a process generally inv...
financially supported by grants from the National Natural Science Foundation of China (Nos.31522035,31371460 and 31590832)
Prpf4 (pre-mRNA processing factor 4), a key component of spliceosome, plays critical roles in pre-mRNA splicing and its mutations result in retinitis pigmentosa due to photoreceptor defects. In this study, we charac...
supported by the Fundamental Research Funds for the Central Universities(2662017PY013 and 2662015PY101);the Autonomous Project of State Key Laboratory of Freshwater Ecology and Biotechnology(2011FBZ22);the Autonomous Projects of the Institute of Hydrobiology,Chinese Academy of Sciences(Y25A17 and Y45A171301)
Signal transducer and activator of transcription 5b(STAT5b) has been identified as a key downstream mediator of growth hormone(GH) signaling in somatic growth of mammalian. However, the corresponding homologue gen...