FELODIPINE

作品数：20被引量：18H指数：3
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相关领域：医药卫生更多>>
相关作者：司良毅赵学张远慧王国超周烨胤更多>>
相关机构：第三军医大学哈尔滨医科大学第三军医大学附属第一医院中南大学更多>>
相关期刊：《Advances in Microbiology》《Chemical Research in Chinese Universities》《Cellular & Molecular Immunology》《药学进展》更多>>
相关基金：国家自然科学基金上海市青年科技启明星计划更多>>
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A SARS-CoV-2-specific CAR-T-cell model identifies felodipine,fasudil,imatinib,and caspofungin as potential treatments for lethal COVID-19
《Cellular & Molecular Immunology》2023年第4期351-364,共14页in Xia Lun-zhi Yuan Ya-hong Hu Jun-yi Liu Guo-sheng Hu Ruo-yao Qi Tian-ying Zhang Hua-long Xiong Zao-zao Zheng Hong-wei Lin Jia-mo Zhang Chao Yu Ming Zhou Jian Ma Tong Cheng Ri-rong Chen Yi Guan Ning-shao Xia Wen Liu 
Fundamental Research Funds for the Central Universities(20720200104)to LX;the Ministry of Science and Technology of China(2020YFA0112300 and 2020YFA0803600);the National Natural Science Foundation of China(82125028,U22A20320,91953114,31871319,81761128015,and 81861130370);the Natural Science Foundation of Fujian Province of China(2020J02004);the Fundamental Research Funds for the Central University(20720190145 and 20720220003)to WL;the China Postdoctoral Science Foundation(2022M720119)to ZZZ.Part of Fig.6 was drawnbyusingFigdraw.
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019(COVID-19)severity and lethality.However,drugs that are effective against inflammat...
关键词：COVID-19 SARS-CoV-2 CAR-T anti-inflammation NF-kB pathway 
Felodipine enhances aminoglycosides efficacy against implant infections caused by methicillin-resistant Staphylococcus aureus,persisters and biofilms被引量：1
《Bioactive Materials》2022年第8期272-289,共18页Shutao Zhang Xinhua Qu Juyang Jiao Haozheng Tang Minqi Wang You Wang Hongtao Yang Weien Yuan Bing Yue 
supported by the National Natural Science Foundation of China(Grant No.82172464,82172453,81972086);National Key Research and Development Project of China(Grant No.2020YFC1107500,2020YFC1107503);The Shanghai Rising-Star Program(21QA1405500);Shanghai“Rising Stars of Medical Talent”Youth Development Program(Youth Medical Talents-Specialist Program)(Grant No.2019-72);“Technology Innovation Action Plan”Key Project of Shanghai Science and Technology Commission(Grant No.19411962800);Shanghai municipal education commission-Gaofeng clinical medicine grant support(Grant No.20161423);NSFC Advancing Targeted Projects(RJTJ-JX-005,RJTJ22-RC-011).
Methicillin-resistant Staphylococcus aureus(MRSA),biofilms,and persisters are three major factors leading to recurrent and recalcitrant implant infections.Although antibiotics are still the primary treatment for chron...
关键词：AMINOGLYCOSIDES FELODIPINE Persisters Methicillin-resistant Staphylococcus aureus Implant infection 
Study of the Reactivity of (100) Felodipine Surface Model Based on DFT Concepts
《Open Journal of Physical Chemistry》2019年第1期1-12,共12页Carlos Tepech-Carrillo Roxana Licona-Ibarra J. Francisco Rivas-Silva Antonio Flores-Riveros 
In this study, Density Functional Theory including a dispersion correction is employed to model and analyze the structural, electronic and local reactivity of the (100) surface of felodipine. The surface energy calcul...
关键词：1 4-Dihydropyridine FELODIPINE Density FUNCTIONAL Theory Fukui FUNCTIONS 
Effect of felodipine in combined with irbesartan on the blood uric acid,serum adiponectin,and renal function in young males with essential hypertension
《Journal of Hainan Medical University》2017年第18期27-30,共4页Jing Wang Yan-Li Liu 
Objective: To explore the effect of felodipine in combined with irbesartan on the blood uric acid (UA);serum adiponectin (APN);and renal function in young males with essential hypertension (EH). Methods: A total of 13...
关键词：FELODIPINE IRBESARTAN YOUNG males EH UA APN RENAL function 
Enantioselective Conversion of Racemic Felodipine to S(-)-Felodipine by Aspergillus niger and Lipase AP6 Enzyme
《Advances in Microbiology》2016年第14期1062-1074,共14页Chandupatla Vijitha Ettireddy Swetha Ciddi Veeresham 
The present study involves the enantioselective resolution of racemic Felodipine by using free and immobilized forms of microbial cultures as well as an enzyme (Lipase AP6). Among the microbial cultures employed in th...
关键词：Racemic Felodipine Enantioselective Conversion BIOCATALYSTS Immobilization Lipase AP6 
Pharmacokinetics of two components in felodipine-enalapril sustained-release tablets in Chinese healthy volunteers
《Journal of Chinese Pharmaceutical Sciences》2015年第7期427-432,共6页吕伊莎 冉黎灵 吴蔚 李三望 周瑞 唐芳 余鹏 牟玲丽 程泽能 
National Natural Science Foundation of China(Grant No.81102499);supported by Hunan Science and Technology Project(Grant No.2011SK3261,Changsha,China)
To compare the pharmacokinetics properties of enalapril-felodipine sustained-release tablet with enalapril and felodipine in the two reference formulations in Chinese healthy volunteers, the study was designed to a ra...
关键词：FELODIPINE ENALAPRIL ENALAPRILAT PHARMACOKINETICS 
The influence of CYP3A5 ＊ 3 and BCRPC421A genetic polymorphisms on the pharmacokinetics of felodipine in healthy Chinese volunteers
《中国药理学通报》2015年第B11期215-215,共1页
Aim The aim of this study was to evaluate the pharmacogenetic variability in the disposition of felodip- ine in healthy Chinese subjects. Methods A single oral dose of 5 mg felodipine was orally administered to 45 hea...
关键词：FELODIPINE CHINESE CYP3A5 BCRPC421A PHARMACOKINETICS 
High performance liquid chromatographic separation of eight drugs collected in Chinese Pharmacopoeia 2010 on amylose ramification chiral stationary phase被引量：3
《Acta Pharmaceutica Sinica B》2012年第5期527-533,共7页Yan Wang Ying Zhou Chao Ma Beibei Yang Ru Feng Yiying Zhang Jie Fu Wenjing Chen Yupeng Sun Jingyi Ma Qiming Zhang Yulin Deng Yukui Zhang Wenyi He 
The enantiomers separation of ei ght pharmaceutical racemates collected in Chinese Pharmacopoeia 2010(Ch.P2010),including nitrendipine,felodipine,omeprazole,praziquantel,sulpiride,clenbuterol hydrochloride,verapamil h...
关键词：Normal phase HPLC Chiral stationary phase Optical enantiomers Amylose ramification NITRENDIPINE FELODIPINE Omeprazole Praziquantel SULPIRIDE Clenbuterol hydrochloride Verapamil hydrochloride Chlorphenamine maleate 
Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-κB activation被引量：3
《Acta Pharmacologica Sinica》2008年第9期1051-1059,共9页Hong-wei TAN 
This study was supported by research funding by AstraZeneca Pharmaceutical Co Ltd China （QD02 to Dr Wei ZHANG） and by the National Natural Science Foundation of China （No 30670874 to Dr Wei ZHANG）. Hong-wei TAN and Wei ZHANG designed research; Shah-shah XING, Xiu-ping BI, and Hui-ping GONG performed research; Ming ZHANG contributed new analytical tools and reagents; Hong-wei TAN and Li LI analyzed data; Hong-wei TAN, Yun ZHANG, and Wei ZHANG wrote the paper.
Aim： Metabolic syndrome is associated with an increased incidence of atherosclerosis. Clinical studies have shown that calcium channel blockers （CCB） inhibit the progression of atherosclerosis. However, the underly...
关键词：calcium channel blocker fructose-fed rat metabolic syndrome adhesion molecule 
非洛地平缓释片联合开搏通治疗高血压的临床疗效观察
《中外健康文摘：医药月刊》2008年第7期762-763,共2页邓卫雄 
目的观察非洛地平缓释片联合开搏通治疗高血压的临床疗效。方法2005年3月～2008年5月期间68例高血压患者，随机均分为两组；对照组单纯采用开搏通治疗，观察组在对照组的基础上加用非洛地平缓释片联合治疗；观察两组的治疗效果。结果与...
关键词：非洛地平缓释片 (Felodipine SUSTAINED-RELEASE Tablets) 疗效 高血压 开搏通(Captopril) 
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