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Phosphoglucose isomerase gene expression as a prognostic biomarker of gastric cancer被引量：1: 《Chinese Journal of Cancer Research》2019年第5期771-784,共14页Han-Chen Huang Xian-Zi Wen Hua Xue Run-Sheng Chen Jia-Fu Ji Lei Xu; supported by grants from the Ministry of Science and Technology of the People’s Republic of China (No. SS2014AA020603);Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (No. ZYLX201701);Beijing Municipal Science and Technology Commission (No. D1311 00005313010);the National Natural Science Foundation of China (No. 31520103905);the National High Technology Research and Development Program (“863” Program) of China (No. 2015AA020108);the Zhi-Yuan chair professorship start-up grant WF220103010 from Shanghai Jiao Tong University; Objective: Tumor heterogeneity renders identification of suitable biomarkers of gastric cancer(GC)challenging. Here, we aimed to identify prognostic genes of GC using computational analysis.Methods: We first used micr...; 关键词：GASTRIC cancer gene expression profile PROGNOSTIC BIOMARKER phosphoglucose ISOMERASE tumor metabolism

Inhibition of HOXB7 Gene Expression in Melanoma Cells by Small Interfering RNA: 《Chinese Journal of Cancer Research》2008年第2期90-99,共10页葛林虎彭思达谭获王春燕于宝丹郑丽霞叶絮; the grants from the Research Foundation of Science & Technology Bureau of Guangzhou(2004Z2-E0011);the Guangdong Province Natural Science Foundation(5002318); Objective： HOXB7 gene is a kind of transcription regulator over-expressed in malignant melanoma （MM） cell lines. It can specifically up-regulate the expression of angiogenic factors and tumor growth factors such as...; 关键词：Small interference RNA Malignant melanoma cell HOXB7 gene bFGF gene siRNA expression vector

ESTROGEN REGULATION OF LRP16 GENE EXPRESSION INVOLVES SP1 TRANSCRIPTION FACTOR: 《Chinese Journal of Cancer Research》2006年第4期251-256,共6页司艺玲韩为东赵亚力李琦郝好杰宋海静母义明于力; This work was supported by the NationaNatural Science Foundation of China (No.30572096) andBeijing Natural Science Foundation (No.5052024).; Objective： To investigate the role of Spl as transcription factor required for transactivation of LRP16 gene by estrogen. Methods： Specific antibodies of ERα and Spl were used to precipitate the target DNA/protein...; 关键词：SP1 LRP16 gene Small interference RNA ESTROGEN Gene expression

TRICHOSTATIN A INHIBITS PROLIFERATION,INDUCES APOPTOSIS AND CELL CYCLE ARREST IN HELA CELLS被引量：1: 《Chinese Journal of Cancer Research》2006年第3期188-192,共5页徐周敏汪宜群梅琪陈坚杜佳魏燕徐迎春; Objective： The histone deacetylase inhibitors （HDACIS） have been shown to inhibit cancer cell proliferation, stimulate apoptosis, an induce cell cycle arrest. Our purpose was to investigate the antiproliferative ef...; 关键词：Trichostatin A HeLa cells APOPTOSIS Cell cycle Gene expression

EXPRESSION OF INTRON 9 IN CD44 GENE IN CERVICAL CANCER AND CIN AND ITS CLINICAL SIGNIFICANCE: 《Chinese Journal of Cancer Research》2006年第1期57-61,共5页王敏高岩王欣彦张颖; Objective： To detect the retention of intron 9 in CD44 mRNA in cervical cancer tissue, CIN, cervicitis and their exfoliated cells, and to study their clinical significance in diagnosis and treatment of early-stage, n...; 关键词：Cervical cancer CIN CD44 gene Gene expression

GROWTH-INHIBITORY EFFECTS OF CURCUMIN ON Raji CELLS AND ITS MECHANISMS: 《Chinese Journal of Cancer Research》2005年第3期203-206,共4页陈燕吴青李新刚; This work was supported by the National Natural Science Foundation of China (No. 30271672).; Objective： To study the growth-inhibitory effects of curcumin on B-NHL cell line Raji cells in vitro and its molecular mechanisms. Methods： The growth inhibition rates of Raji cells, after being treated with 6.25μm...; 关键词：CURCUMIN Raji cell Gene expression APOPTOSIS

THE EFFECT OF RNAI-MEDIATED GENE SILENCING ON HER-2/NEU GENE EXPRESSION IN LUNG ADENOCARCINOMA CELLS被引量：2: 《Chinese Journal of Cancer Research》2005年第2期84-89,共6页任淑华王井伟曲平刘义张伟张林; This work was supported by the NationalNatural Science Foundation of China (No.30371624).; Objective: Her-2/neu protein overexpression has been demonstrated in Non-small cell lung cancer, especially in lung adenocarcinoma. Its overexpression often indicates a poor prognosis. Therapeutic agents against her-2...; 关键词：RNAI HER-2/NEU Lung adenocarcinoma cells SIRNA

A POTENTIAL TUMOR SUPPRESSOR GENE: Doc-1R被引量：2: 《Chinese Journal of Cancer Research》2004年第1期15-19,共5页生秀杰周伟强姜莉张梅英王太一张学; Thisworkwassupportedbythenational9thFive-YearplanResearchProgramofChina(No.96-A230602)andtheNationalNaturalScienceFoundationofChina(No.39980011).; Objective: To detect the expression and the genomic sequence of Doc-1R gene in mice. Methods: The gene specific primers were designed and synthesized according to the cDNA sequence of Doc-1R gene. The sequence of Doc-...; 关键词：DOC-1R DNA sequencing Gene expression

UP-REGULATION OF CYCLOOXYGENASE-2 GENE EXPRESSION CORRELATES WITH TUMOR ANGIOGENESIS IN HUMAN BREAST CANCER被引量：2: 《Chinese Journal of Cancer Research》2003年第2期149-151,156,共4页代志军王西京刘小旭康华峰姜建涛管海涛张淑群薛兴欢薛锋杰; Objective: To study the relationship between cyclooxygenase-2 (COX-2) expression and tumor angiogenesis in human breast cancer. Methods: Archival primary breast carcinomas (n = 62), adjacent ductal carcinoma in situ (...; 关键词：Breast carcinoma CYCLOOXYGENASE-2 VEGF Microvessel density

GENE EXPRESSION OF NOVEL RETROVIRUS ASSOCIATED WITH HUMAN ACUTE MULOID LEUKEMIA: 《Chinese Journal of Cancer Research》2003年第2期98-101,共4页许晓华徐荣臻王世炯郑树朱宁希周旋; this study was supported by the National Natural Science Foundation of China(No. 39670326).; Objective: To explore the potentiality of retroviral etiology in human acute myeloid leukemia(AML). Methods: The expression of clone 6#11 in leukemic cell samples from 19 AML cases and peripheral blood mononuclear cel...; 关键词：Gene expression RETROVIRUS Acute myeloid leukemia

GENE_EXPRESSION