GENE_EXPRESSION_PROFILE

作品数:110被引量:309H指数:9
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Gene Expression Profile Identifies LncRNA AL355974.3 As a Potential Glioma Biomarker
《Current Medical Science》2024年第5期1047-1057,共11页Hao-tian LU Yu-yang CHEN Yong-jia YU Xing-sheng LIAO Hui LIANG Lun LIANG Pan-lin MO Xin-kai HUANG Shuai DING Chang LIU Da-qin FENG 
supported by grants from the National Natural Science Foundation of China(No.82260554);Natural Science Foundation of Guangxi Province(No.2023GXNSFBA026092 and No.2024GXNSFAA010100);Key Research and development Program of Guangxi Province(No.2023AB22116).
Objective Glioma is a central nervous system tumor arising from glial cells.Despite significant advances in diagnosis and treatment,most patients with high-grade gliomas have a poor prognosis.Many studies have shown t...
关键词:GLIOMA long noncoding RNAs BIOMARKER RNA sequencing 
Epigenetic control on transcription of vernalization genes and whole-genome gene expression profile induced by vernalization in common wheat
《Plant Diversity》2024年第3期386-394,共9页Yunzhen Li Liujie Jin Xinyu Liu Chao He Siteng Bi Sulaiman Saeed Wenhao Yan 
supported by Project 2662020ZKPY002 supported by the Fundamental Research Funds for the Central Universities.
Vernalization is necessary for winter wheat to flower.However,it is unclear whether vernalization is also required for spring wheat,which is frequently sown in fall,and what molecular mechanisms underlie the vernaliza...
关键词:WHEAT VERNALIZATION VRN1 Histone modification Regulate network 
Identifying genetic susceptibility to Aspergillus fumigatus infection using collaborative cross mice and RNA-Seq approach
《Animal Models and Experimental Medicine》2024年第1期36-47,共12页Roa'a H.S.Yosief Iqbal M.Lone Aharon Nachshon Heinz Himmelbauer Irit Gat-Viks Fuad A.Iraqi 
European Sequencing and Genotyping Institutes(ESGI),Grant/Award Number:075491/Z/04,085906/Z/08/Z and 090532/Z/09/Z;Tel-Aviv University(TAU)。
Background:Aspergillus fumigatus(Af)is one of the most ubiquitous fungi and its infection potency is suggested to be strongly controlled by the host genetic back-ground.The aim of this study was to search for candidat...
关键词:aspergillus fumigatus infection collaborative cross(CC)mice gene expression profile gene-network host susceptibility quantitative trait loci(QTL)mapping RNA-SEQ 
Effect of Chuanzhifang component (ZGC) on macrophage inflammatory injury based on whole gene expression profile
《Journal of Hainan Medical University》2024年第3期15-22,共8页JIANG Jie AN Wan-li YANG Zhi-qian CHENG Wen-hui YANG Hong 
Chinese Academy of Traditional Chinese Medicine Autonomous Topic Selection Project(No.ZZ2018017);Research Development Fund Project of the Medical Experimental Center of the Chinese Academy of Traditional Chinese Medicine(No.FZ2023003)。
Objective: The effect of Chuanzhi Fang (ZGC) on the whole genome expression profile of RAW264.7 cells activated by lipopolysaccharide (LPS) was analyzed, and to explore the possible mechanism of action and core target...
关键词:Chinese herbal medicine component Chuanzhifang(ZGC) RAW264.7 cell CYTOKINE Gene expression profiling 
Transcriptional regulatory network during axonal regeneration of dorsal root ganglion neurons:laser-capture microdissection and deep sequencing被引量:1
《Neural Regeneration Research》2023年第9期2056-2066,共11页Li-Li Zhao Tao Zhang Wei-Xiao Huang Ting-Ting Guo Xiao-Song Gu 
supported by the National Natural Science Foundation of China,Nos. 31730031 and 32130060;the National Major Project of Research and Development,No. 2017YFA0104700;the Natural Science Foundation of Jiangsu Province,No. BK20202013 (all to XSG)。
The key regulators and regeneration-associated genes involved in axonal regeneration of neurons after injury have not been clarified.In high-throughput sequencing,various factors influence the final sequencing results...
关键词:Arid5a ATF3 Crem dorsal root ganglion Fosl1 KLF6 laser-capture microdissection NEURON smart-seq2 gene expression profile transcription factor 
Deep Contextual Representation Learning for Identifying Essential Proteins via Integrating Multisource Protein Features
《Chinese Journal of Electronics》2023年第4期868-881,共14页LI Weihua LIU Wenyang GUO Yanbu WANG Bingyi QING Hua 
This work was supported by the National Natural Science Foundation of China(32060151,62062066,61762090);the Doctor Scientific Research Fund of the Zhengzhou University of Light Industry(2021BSJJ032).
Essential proteins with biological functions are necessary for the survival of organisms.Computational recognition methods of essential proteins can reduce the workload and provide candidate proteins for biologists.Ho...
关键词:Essential proteins Protein interaction networks Gene expression profile Deep neural networks 
RNA-sequencing-based Gene Expression Profile Revealing Breast Tumor Development Induced by Exposure of Bisphenol S
《Chemical Research in Chinese Universities》2023年第3期441-448,共8页ZHOU Peng XIAO Yu ZHOU Xin LIU Jianjun ZHAO Chao 
supported by the National Natural Science Foundation of China(No.22176195);the Natural Science Foundation of Guangdong Province,China(No.2021A1515010171);the Key Program of Fundamental Research in Shenzhen,China(NoJCYJ20210324115811031);the Shenzhen Key Laboratory of Precision Diagnosis and Treatment of Depression,China(No.ZDSYS20220606100606014);the Shenzhen Key Medical Discipline Construction Fund,China(No.SZXK052);the Clinical Research Project of Shenzhen Second People’s Hospital,China(No.20203357001);the Guangdong Basic and Applied Basic Research Foundation,China(No.2021A1515110096).
Aberrant biological information occurs naturally at exposure to bisphenol A or its alternatives,which was associated with the occurrence and development of breast cancer.However,the potential molecular variation in ge...
关键词:Bisphenol S RNA-sequencing Breast cancer Tumor development 
Analysis of gene expression profile for identification of novel gene signatures during dengue infection
《Infectious Medicine》2023年第1期19-30,共12页Jhansi Venkata Nagamani Josyula Prathima Talari Agiesh Kumar Balakrishna Pillai Srinivasa Rao Mutheneni 
Background:Dengue is a major arthropod-borne viral disease spreading rapidly across the globe.The absence of vaccines and inadequate vector control measures leads to further expansion of dengue in many regions globall...
关键词:Dengue fever Severe dengue MICROARRAY Gene expression Data analysis Gene signatures 
Comprehensive Analysis of Differential Gene Expression Profile via RNA Sequencing in the Human Ovarian Cancer SKOV3 Cells Treated with Simvastatin
《Chemical Research in Chinese Universities》2022年第2期632-638,共7页LIU Qianyu DU Zhenwu ZHU He ZHAO Tianyu PAN Ying 
supported by the Jilin Science and Technology Funds,China (Nos.20180101165JC,2020SC2T042).
The experimental studies have demonstrated that some statins have an anticancer effect against ovarian cancer in vitro and in vivo, however, the potential molecular mechanism is still unclear. In the present study, hi...
关键词:SIMVASTATIN Ovarian cancer RNA sequencing Gene expression profile 
Network pharmacology-based approach to investigate the mechanism of Huang-Lian-Jie-Du-Decoction for treatment of type 2 diabetes mellitus
《Traditional Medicine Research》2021年第4期87-103,共17页Hui-Ling Li Chen Chen Chao Chen 
the Natural Science Foundation of Guangdong Province(No.2016A030313837).
Background:Although the benefits of Huang-Lian-Jie-Du-Decoction(HLJDD)on type 2 diabetes mellitus are noted,the material base and action mechanism remain unknown.This paper aim is to reveal the material base and actio...
关键词:Huang-Lian-Jie-Du-Decoction Type 2 diabetes mellitus Gene expression profile GEO database Network analysis Molecular docking 
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