supported by the National Natural Science Foundation of China,No.81472162(to MKZ)
Single-nucleotide polymorphisms in the brain-derived neurotrophic factor gene may affect the secretion and function of brain-derived neurotrophic factor, thereby affecting the occurrence, severity and prognosis of isc...
supported by a grant from the National Natural Science Foundation of China,No.81070913
Thromboxane A synthase 1 (TBXAS1) catalyses the synthesis of thromboxane A2 (TXA2), which plays an important role in the pathogenesis of ischemic stroke. Thus, the TBXAS1 gene was investigated as a candidate gene ...
funded by the National Natural Science Foundation of China,No.81360434
Developmental dyslexia is a complex reading and writing disorder with strong genetic components. In previous genetic studies about dyslexia, a number of candidate genes have been identified. These include DCDC2, which...
supported by the National Natural Science Foundation of China;No.81171867;a grant from the Key Research Program of Fujian Department of Science and Technology of China;No.2011Y0027
Evidence suggests that interleukin-10(IL-10) deficiency exacerbates inflammation and worsens the outcome of brain ischemia. In view of the critical role of the single nucleotide polymorphic sites-1082(A/G) and-819...
supported by the National Natural Science Foundation of China,No.81370445,81061120527,81241082;Major Funding from Beijing Hospital,No.BJ-2010-30;Key Project of Clinical Disciplines at the Subordinate Hospital,Ministry of Health,No.10120101;National Department Public Benefit Research Foundation by the Ministry of Health,No.201302008;12th 5-year National Program from Ministry of Scientific Technology,No.2012BAI10B01;Science and Technology Development Foundation of Guangxi Zhuang Autonomous Region,No.1355005-62;Canadian Institute of Health Research(CIHR),No.109606
Current evidence shows that apolipoprotein E (APOE), apolipoprotein CI (APOC1) and low density lipoprotein receptor-related protein (LRP) variations are related to late-onset Alzheimer's disease. However, it re...
supported by two grants from Science,Industry,Trade and Information Technology Commission of Shenzhen Municipality in China,grant No.201002063,JC20110518075 7A
The apolipoprotein E gene ε4 allele is considered a negative factor for neural regeneration in late-onset Alzheimer's disease cases. The aim of this study was to establish a non-invasive, rapid method to genotype ap...
Atherosclerosis plays an important role in ischemic stroke, and oxidative stress participates in the entire process of atherosclerosis. Glutathione S-transferase (GST) acting with other antioxidant enzymes can elimi...
supported by grants from the National Natural Science Foundation of China, No. 30770770,30971054;Personnel Returned Overseas Research Foundation of Shanxi Province, No. 2007-48;Science Foundation for Youths of Shanxi Province, No. 2010021036-3;the Special Fund Talent of Shanxi Province, Foundation for Youths of Shanxi Province, No. 2011021036-1
For this study, 461 Chinese Han patients with depressive disorder were recruited. The AKT1 genotype and allele distribution were determined by PCR amplification and direct sequencing. UNPHASED software was used to ana...
OBJECTIVE: To investigate the association of E-selectin $128R polymorphisms with ischemic stroke. DATA SOURCES: A computer-based online search was conducted in PubMed, Elsevier, Ovid Database, the China National Kno...
Serotonin (5-hydroxytryptamine, 5-HT) influences the cortical and subcortical excitatory/inhibitory balance and participates in the pathophysiological processes of epilepsy. The serotonin transporter (5-HTT) is th...