GENE_TRANSFER

作品数:204被引量:510H指数:11
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相关作者:王晶江洪黄从新李庚山李建军更多>>
相关机构:武汉大学中国医学科学院阜外心血管医院大连民族大学青岛大学医学院附属医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划湖北省自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Lentiviral-mediated vascular endothelial growth factor 165 gene transfer into neural stem cells promotes proliferation被引量:1
《Neural Regeneration Research》2011年第19期1457-1461,共5页Shanshan Zhang Xiangrong Zheng Fei Yin Jielu Tan Yujia Yang 
the National Natural Science Foundation of China, No. 30772341, 81070523
We constructed a lentiviral vector carrying vascular endothelial growth factor 165, which was used to transfect neural stem cells. The transfection rate was approximately 50%, as determined by flow cytometry. Vascular...
关键词:vascular endothelial growth factor 165 gene therapy LENTIVIRUS neural stem cells TRANSFECTION 
Effect of adenovirus-mediated gene transfer of Olig1 on oligodendrocyte differentiation and remyelination in a rat model of focal cerebral ischemia被引量:1
《Neural Regeneration Research》2009年第11期862-867,共6页Hong Zhao Xiaoyu Gao Dexin Wang Yongbo Zhang 
the National Natural Science Foundation of China,No.30570626;the Natural Science Foundation of Beijing,No.7082028
BACKGROUND: The transcription factor Oligl is required for oligodendrocyte maturation and demyelinated lesion repair, and is a key regulator of myelinogenesis following ischemia. OBJECTIVE: To examine the efficacy o...
关键词:Oligl gene therapy cerebral ischemia rats OLIGODENDROCYTES REMYELINATION 
Effects of kallikrein gene transfer on penumbral microvascular proliferation and on regional cerebral blood flow following cerebral ischemia/reperfusion injury
《Neural Regeneration Research》2008年第10期1045-1050,共6页Ruiyan Lu Qingyu Shen Lianhong Yang Mei Li Yidong Wang Ying Peng 
Supported by: the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of China, No. D002006006
BACKGROUND: Recent findings have demonstrated that the kallikrein-kinin system (KKS) participates in the pathological process of cerebral ischemia/reperfusion injury. Kallikrein gene transfer exhibits neural protec...
关键词:cerebral ischemia ischemia/reperfusion injury ADENOVIRUS gene transfer KALLIKREIN vascular endothelial growth factor perfusion  regional 
Hepatocyte growth factor gene transfer effects on the femoral and intramuscular nerve in a canine model of lower limb ischemia被引量:1
《Neural Regeneration Research》2008年第6期625-628,共4页Xiaoqin Ha Bin Liu Zhen Qian Tongde LU Ling Hui Guanxian He Qiang Yin Tingxian Niu 
the Foundation of High-Tech Key Project of the National 863 Program, No. 2001AA217061
BACKGROUND: Recent advancements in gene therapy have provided new methodology for treating ischemia in lower extremities. Gene transfer of angiogenic factors to ischemic tissues may promote local proliferation of new...
关键词:hematopoietic reconstitution hepatocyte growth factor HISTOPATHOLOGY lower limb ischemia NERVE recombinant plasmid 
Adenovirus-mediated hypoxia-inducible factor-1 alpha gene transfer induces angiogenesis and neurogenesis following cerebral ischemia in rats
《Neural Regeneration Research》2008年第4期378-383,共6页Wanfu Wu Xiu Chen Zhen Yu Changlin Hu Wenqin Cai 
Key Program of Chongqing Municipal Health Bureau,No. 06-01-020
BACKGROUND: Hypoxia-inducible factor-1 (HIF-1) accumulates under conditions of hypoxia. HIF-1α target genes have pleiotropic effects on neurogenesis, neuroprotection and angiogenesis in the brain. OBJECTIVE: To i...
关键词:hypoxia-inducible factor-1α RATS ANGIOGENESIS NEUROGENESIS focal ischemia 
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