Supported by the Scientific Research Project of Shanghai Municipal Health Commission(No.202140416);the Clinical Research Boosting Program of the Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(No.JYLJ202117).
AIM:To investigate the refractive and the histological changes in guinea pig eyes after posterior scleral reinforcement with scleral allografts.METHODS:Four-week-old guinea pigs were implanted with scleral allografts,...
The main objective of this study was to evaluate the pharmacological potential of the hydroethanol extract of Strychnos camptoneura trunk bark on reproductive functions in male guinea pigs exposed to cypermethrin. The...
Supported by the National Natural Science Foundation of China(No.81400428);Self-selected Projects of Shanghai Children’s Hospital(No.2020R124);Shanghai Children’s Hospital Hospital-level Project Clinical Research Cultivation Special Focus Project(No.2021YLYZ03).
AIM:To quantitatively measure ocular morphological parameters of guinea pig with Python technology.METHODS:Thirty-six eyeballs of eighteen 3-weekold guinea pigs were measured with keratometer and photographed to obtai...
Supported by National Key R&D Program of China(No.2021YFC2702103,No.2021YFC2702100);the National Natural Science Foundation of China(No.82104937);the Key R&D Program of Shandong Province(No.2019GSF108252).
AIM:To investigate the effect of electroacupuncture(EA)on the mitochondria-dependent apoptotic signaling pathway in the ciliary muscle of guinea pigs with negative lensinduced myopia(LIM).METHODS:Guinea pigs were rand...
Supported by the National Key Research and Development Program(Nos.2021YFC2702103,2019YFC1710204);the Key Research and Development Program of Shandong Province(No.2019GSF108252);the Natural Science Foundation of Shandong Province(No.ZR2020MH393)。
Objective:To explore the underlying mechanism of inhibition by Jingui Shenqi Pills(JGSQP)on glucocorticoid-enhanced axial length elongation in experimental lens-induced myopia(LIM)guinea pigs.Methods:Sixty 2-week old ...
This work was supported by grants from the National Natural Science Foundation of China(Grant No.81870681);the Natural Science Foundation of Hainan Province(Grant No.817364).
Background:The use of ocular hypotensive drugs has been reported to attenuate myopia progression.This study explores whether brimonidine can slow myopia progression in the guinea pig form-deprivation(FD)model.Methods:...
BACKGROUND Many studies have shown that interstitial Cajal-like cell(ICLC)abnormalities are closely related to a variety of dynamic gastrointestinal disorders.ICLCs are pacemaker cells for gastrointestinal movement an...
Vocational Education Teaching Reform Project of Hunan Province in 2021(ZJBZ2021034);Special Scientific Research Project of Excellent Management Talents Training Plan of Hunan Polytechnic of Environment and Biology(PY-2021-01).
Guinea pig is widely used in clinical drug experiments as a laboratory animal.Because of its small and lovely size,guinea pig is often kept as a pet by many families.However,there are few reports on the feeding manage...
Supported by the Pudong New Area Clinical Traditional Chinese Medicine of Top Discipline Project,No.PDZY-2018-0603 and the Featured Clinical Discipline Project of Shanghai Pudong,No.PWYts2021-06.
BACKGROUND Impaired interstitial cells of Cajal(ICCs)are central to the pathophysiology of acute cholecystitis(AC).Common bile duct ligation is a common model of AC,producing acute inflammatory changes and decrease in...
Supported by the Key Research Plan of Shaanxi Province,China(No.2018SF-257);the Key Project of Equipment Scientific Research(No.172B02027)。
AIM:To explore the effects of laser-activated remote phosphors(LARP)on visual function in guinea pigs.METHODS:Electroretinogram(ERG)of guinea pigs were observed after LARP irradiation at different frequencies and irra...