IMMUNO

作品数：466被引量：1235H指数：18
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SARS-CoV-2 induced liver injury:Incidence,risk factors,impact on COVID-19 severity and prognosis in different population groups
《World Journal of Gastroenterology》2023年第16期2397-2432,共36页George D Liatsos 
Liver is unlikely the key organ driving mortality in coronavirus disease 2019(COVID-19)however,liver function tests(LFTs)abnormalities are widely observed mostly in moderate and severe cases.According to this review,t...
关键词：COVID-19 SARS-CoV-2 Liver injury Cytokine storm Endotheliopathy Immuno-thromboinflammation Direct hepatocyte injury 
Prognostic significance of hemoglobin,albumin,lymphocyte,platelet in gastrointestinal stromal tumors:A propensity matched retrospective cohort study被引量：2
《World Journal of Gastroenterology》2022年第27期3476-3487,共12页Zhou Zhao Xiao-Nan Yin Jian Wang Xin Chen Zhao-Lun Cai Bo Zhang 
Supported by National Natural Science Foundation of China,No.81572931;The 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYJC18034.
BACKGROUND The combined index of hemoglobin,albumin,lymphocyte,and platelet(HALP)can reflect systemic inflammation and nutritional status simultaneously,with some evidence revealing its prognostic value for some tumor...
关键词：Gastrointestinal stromal tumors Nutrition assessment Immuno-inflammatory-based prognostic scores Prognosis Propensity score 
Hepatitis B:Who should be treated?-managing patients with chronic hepatitis B during the immune-tolerant and immunoactive phases被引量：11
《World Journal of Gastroenterology》2021年第43期7497-7508,共12页Miwa Kawanaka Ken Nishino Hirofumi Kawamoto Ken Haruma 
New hepatitis B virus(HBV)infections are decreasing owing to improved antiviral therapy and increased HBV vaccination worldwide;however,the number of HBV infections remains a major cause of liver carcinogenesis.HBV tr...
关键词：Hepatitis B Immune tolerance Immune-inactive Anti-viral therapy Hepatocellular carcinoma CIRRHOSIS 
Exploring the food-gut axis in immunotherapy response of cancer patients被引量：1
《World Journal of Gastroenterology》2020年第33期4919-4932,共14页Edda Russo Giulia Nannini Monica Dinu Giuditta Pagliai Francesco Sofi Amedeo Amedei 
Supported by the Italian Ministry of University and Research,the Foundation“Ente Cassa di Risparmio di Firenze”FCR 2017;Italian Ministry of Health(Ricerca Finalizzata 2016),No.GR-2016-02361162.
Nowadays,immunotherapy is widely used to treat different cancer types as it boosts the body's natural defenses against the malignancy,with lower risk of adverse events compared to the traditional treatments.The immune...
关键词：Immune response IMMUNOTHERAPY Programmed cell death protein 1 PD-L1 Cancer Gut microbiota High fiber diet 
Positron-emission tomography for hepatocellular carcinoma:Current status and future prospects被引量：7
《World Journal of Gastroenterology》2019年第32期4682-4695,共14页Ren-Cai Lu Bo She Wen-Tao Gao Yun-Hai Ji Dong-Dong Xu Quan-Shi Wang Shao-Bo Wang 
Supported by the National Natural Science Foundation of China,No.81760306;the Basic Research on Application of Joint Special Funding of Science and Technology Department of Yunnan Province-Kunming Medical University,No.2018FE001(-291)
Hepatocellular carcinoma(HCC)is one of the leading causes of cancer mortality worldwide.Various imaging modalities provide important information about HCC for its clinical management.Since positron-emission tomography...
关键词：HEPATOCELLULAR CARCINOMA Positron-emission TOMOGRAPHY Radiotracer Immuno-positron EMISSION TOMOGRAPHY 
Clinical assessment and identification of immuno-oncology markers concerning the 19-gene based risk classifier in stage Ⅳ colorectal cancer被引量：2
《World Journal of Gastroenterology》2019年第11期1341-1354,共14页Jong Lyul Lee Seon Ae Roh Chan Wook Kim Yi Hong Kwon Ye Jin Ha Seon-Kyu Kim Seon-Young Kim Dong-Hyung Cho Yong Sung Kim Jin Cheon Kim 
Korea Research Foundation,No.2016R1E1A1A02919844 to Kim JC and No.2017R1A2B1009062 to Roh SA;Ministry of Science,ICT,and Future Planning,Republic of Korea;the Asan Institute for Life Sciences,No.2016-710 to Lee JL
BACKGROUND Genomic profiling of tumors has contributed to the understanding of colorectal cancer(CRC), facilitating diagnosis, prognosis and selection of treatments,including targeted regimens. A report suggested that...
关键词：Colorectal cancer Prognosis Immunotherapy Signaling LYMPHOCYTIC activation molecule family member 7 TRIGGERING receptor EXPRESSED on MYELOID cells 1 
Anti-tumor necrosis factor α therapy associates to type 17 helper T lymphocytes immunological shift and significant microbial changes in dextran sodium sulphate colitis被引量：2
《World Journal of Gastroenterology》2019年第12期1465-1477,共13页Valentina Petito Cristina Graziani Loris R Lopetuso Marco Fossati Alessandra Battaglia Vincenzo Arena Domenico Scannone Gianluca Quaranta Andrea Quagliariello Federica Del Chierico Lorenza Putignani Luca Masucci Maurizio Sanguinetti Alessandro Sgambato Antonio Gasbarrini Franco Scaldaferri 
BACKGROUND Anti-tumor necrosis factor α(TNFα) represents the best therapeutic option to induce mucosal healing and clinical remission in patients with moderate-severe ulcerative colitis. On the other side gut microb...
关键词：Gut microbiota DEXTRAN sodium sulphate COLITIS Immune system T cells MESENCHYMAL lymphnode Tumor NECROSIS factor α 
Advances in immuno-oncology biomarkers for gastroesophageal cancer:programmed death ligand 1,microsatellite instability,and beyond被引量：10
《World Journal of Gastroenterology》2018年第25期2686-2697,共12页Emily M Lin Jun Gong Samuel J Klempner Joseph Chao 
Blockade of the programmed death ligand 1(PD-L1) and programmed cell death 1(PD-1) receptor axis represents an effective form of cancer immunotherapy. Preclinical evidence initially suggested that gastric and gastroes...
关键词：IMMUNOTHERAPY programmed cell DEATH 1 programmed DEATH LIGAND 1 MICROSATELLITE instablility Gastric cancer 
Composition and immuno-stimulatory properties of extracellular DNA from mouse gut flora被引量：4
《World Journal of Gastroenterology》2017年第44期7830-7839,共10页Ce Qi Ya Li Ren-Qiang Yu Sheng-Li Zhou Xing-Guo Wang Guo-Wei Le Qing-Zhe Jin Hang Xiao Jin Sun 
Supported by China Postdoctoral Science Foundation,No.172774;Fund of Key Laboratory of Carbohydrate Chemistry and Biotechnology,Ministry of Education,Jiangnan University,No.KLCCB-KF201603;National Natural Science Foundation of China,No.31201805
AIM To demonstrate that specific bacteria might release bacterial extracellular DNA(e DNA) to exert immunomodulatory functions in the mouse small intestine.METHODS Extracellular DNA was extracted using phosphate buffe...
关键词：Bacterial extracellular DNA FLORA Immunestimulatory property Gut microbiota MOUSE Small intestine 
Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma被引量：17
《World Journal of Gastroenterology》2017年第13期2286-2293,共8页Kashif Asghar Asim Farooq Bilal Zulfiqar Muhammad Usman Rashid 
Tumor cells induce an immunosuppressive microen-vironment which leads towards tumor immune escape. Understanding the intricacy of immunomodulation by tumor cells is essential for immunotherapy. Indoleamine 2,3-dioxyge...
关键词：Hepatocellular carcinoma Hepatitis C virus Hepatitis B virus Indoleamine 2 3-dioxygenase 
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