IMPORTIN

作品数:37被引量:116H指数:6
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相关领域:生物学医药卫生更多>>
相关作者:段志强胡焱嵇辛勤赵佳福熊建民更多>>
相关机构:贵州大学厦门大学九江学院北京大学更多>>
相关期刊:《Cellular & Molecular Immunology》《Science China(Life Sciences)》《中国综合临床》《Virologica Sinica》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划贵州省科学技术基金贵州省科技计划项目更多>>
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Regulation of FLC nuclear import by coordinated action of the NUP62-subcomplex and importinβSAD2
《Journal of Integrative Plant Biology》2023年第9期2086-2106,共21页Gang Chen Danyun Xu Qing Liu Zhichuang Yue Biao Dai Shujuan Pan Yongqiang Chen Xinhua Feng Honghong Hu 
supported by grants from the National Natural Science Foundation(31970730 and 32170721)to H.H;the Baichuan felowship from College of Life Science and Technology,Huazhong Agricultural University to D.X。
Flowering locus C(FLC)is a central transcriptional repressor that controls flowering time.However,how FLC is imported into the nucleus is unknown.Here,we report that Arabidopsis nucleoporins 62(NUP62),NUP58,and NUP54 ...
关键词:FLC flowering time IMPORTIN nuclear import NUCLEOPORIN 
Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importinα7 is counteracted by TBK1-p62 axis-mediated autophagy被引量:5
《Cellular & Molecular Immunology》2022年第10期1168-1184,共17页Xuyuan Wang Li Jiang Guangwen Wang Wenjun Shi Yuzhen Hu Bo Wang Xianying Zeng Guobin Tian Guohua Deng Jianzhong Shi Liling Liu Chengjun Li Hualan Chen 
This investigation was funded by a grant from the Laboratory of Lingnan Modern Agriculture Project(NT2021007 to HC and CL);the National Natural Science Foundation of China(NSFC)(32192453 to CL,32172847 to LJ);the National Key Research and Development Program of China(2021YFD1800203 to HC,2021YFD1800204 to CL);the Natural Science Foundation of Heilongjiang Province(JQ2019C005 to CL);the Central Public-Interest Scientific Institution Basal Research Fund(Y2017JC35 to GT).
As a major component of the viral ribonucleoprotein(vRNP)complex in influenza A virus(IAV),nucleoprotein(NP)interacts with isoforms of importinαfamily members,leading to the import of itself and vRNP complex into the...
关键词:Influenza A virus BinCARD1 TRAF3 TBK1 P62 
The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication被引量:4
《Protein & Cell》2022年第5期360-378,共19页Wan Zhao Junjie Zhu Hong Lu Jiaming Zhu Fei Jiang Wei Wang Lan Luo Le Kang Feng Cui 
the State Key Research Development Program of China(No.2019YFC1200504);the National Natural Science Foundation of China(No.32090012);the National Key R&D Program of China(No.2017YFD0200400);the Collaborative Program between Chinese Academy of Sciences and CSIRO of Australia(No.152111KYSB20190062);the Youth Innovation Promotion Association,CAS(No.2019086).
Rice stripe virus(RSV)transmitted by the small brown planthopper causes severe rice yield losses in Asian countries.Although viral nuclear entry promotes viral replication in host cells,whether this phenomenon occurs ...
关键词:rice stripe virus nucleocapsid protein nuclear localization importinα YY1 
SWO1 modulates cell wall integrity under salt stress by interacting with importinɑin Arabidopsis被引量:2
《Stress Biology》2021年第1期98-119,共22页Zhidan Wang Mugui Wang Changhong Yang Lun Zhao Guochen Qin Li Peng Qijie Zheng Wenfeng Nie Chun-Peng Song Huazhong Shi Jian-Kang Zhu Chunzhao Zhao 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences,Grant XDB27040101(to J-K.Z.);Shanghai Pujiang Program,Grant 20PJ1414800(to C.Z.),and National Natural Science Foundation of China,Grant No.32070295(to C.Z.).
Maintenance of cell wall integrity is of great importance not only for plant growth and development,but also for the adaptation of plants to adverse environments.However,how the cell wall integrity is modulated under ...
关键词:Agenet domain Salt stress IMPORTINS Plant cell wall ARABIDOPSIS 
African Swine Fever Virus MGF360-12L Inhibits Type Ⅰ Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway被引量:34
《Virologica Sinica》2021年第2期176-186,共11页Yisha Zhuo Zeheng Guo Tongtong Ba Cheng Zhang Lihua He Cuiping Zeng Hanchuan Dai 
sponsored by National key Research and Development Program(Grant No.2017YFD0502301);National College Students’innovation and entrepreneurship training program(201910504017)。
African swine fever(ASF)is an infectious transboundary disease of domestic pigs and wild boar and spreading throughout Eurasia.There is no vaccine and treatment available.Complex immune escape strategies of African sw...
关键词:African swine fever virus(ASFV) MGF360-12L IFN-Ⅰ NF-κB Nuclear transport 
猫importin基因生物信息分析及其在犬细小病毒感染F81细胞表达的动态变化
《中国畜牧兽医》2020年第12期3861-3869,共9页赵航 宋姗姗 王建科 林鹏 
国家自然科学基金(3170131433)。
试验旨在系统研究猫源不同亚型importin(importinα1、importinα3、importinα4、importinα5、importinα6、importinα7、importinα8和importinβ)基因序列和蛋白基本特性,探讨其在犬细小病毒(canine parvovirus,CPV)感染F81细胞表...
关键词:输入蛋白 犬细小病毒(CPV) 序列分析 表达差异 
NLS-RARα通过与importin α1/β1(KPNA2/KPNB1)结合入核并抑制U937细胞分化被引量:1
《细胞与分子免疫学杂志》2020年第6期499-506,共8页叶娇 刘北忠 李健 熊玲 余莉华 但文冉 刘冬冬 姚娟娟 袁桢 钟鹏强 刘俊梅 钟梁 
国家自然科学基金(81772280);重庆市科学技术委员会(cstc2018jscx-msybX0173)。
目的探究核定位信号-维甲酸受体α(NLS-RARα)异常的核定位对细胞分化的抑制作用以及其核转运机制。方法过表达带有血凝素(HA)标签的NLS-RARα慢病毒和空载体慢病毒转染HEK293T细胞和U937细胞,设为NLS-RARα过表达组(NR组)和阴性对照组...
关键词:核定位信号 维甲酸受体α(RARα) 细胞分化 核转运蛋白α2/输入蛋白α1(KPNA2/importinα1) 核转运蛋白β1/输入蛋白β1(KPNB1/importinβ1) 
山东农业大学揭示核输入蛋白IMPORTIN β4调控胚珠发育的机制
《蔬菜》2019年第3期7-7,共1页
山东农业大学张彦和李厦课题组揭示了拟南芥核输入蛋白IMPORTIN β4 (IMB4 )通过介导转录激活因子GIFs入核,从而调控胚珠发育的分子机制。课题组综合运用细胞生物学、生物化学、分子生物学,以及遗传学等手段,发现核输入蛋白IMB4功能缺...
关键词:山东农业大学 胚珠发育 分子机制 蛋白 调控 转录激活因子 细胞生物学 分子生物学 
Tip60 Tumor Suppressor Requires Its NLS Motif to Interact with Importin <i>α</i>
《CellBio》2019年第1期1-16,共16页Eun Jeoung Lee Sung Hwa Shin Sang Sun Kang 
Tip60 is a specific member of MYST (Moz-Ybf2/Sas3-Sas2-Tip60) family of nuclear histone acetyltransferases (HAT). It is essential for cellular survival, differentiation, and metabolism. A putative canonical NLS motif ...
关键词:Tip60 IMPORTIN α Nuclear Localization Sequence PROTEIN-PROTEIN Interaction HAT Activity Cell Survival 
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants被引量:5
《Science China(Life Sciences)》2019年第2期257-267,共11页Ye Liu Yinyu Wang Fangfang Wang Jiexue Pan Jingjing Xu Jingyi Li Chengliang Zhou Guolian Ding Yanting Wu Xinmei Liu Jianzhong Sheng Hefeng Huang 
supported by the National Key Research and Development Program of China (2017YFC1001303);International Cooperation Project of China and Canada NSFC (81661128010);National Natural Science Foundation of China (31471405, 81671456, 81671412);the National Key Basic Research Program (2013CB967404); the Doctoral Innovation Fund of School of Medicine, Shanghai Jiao Tong University (BXJ201640)
As shown in our previous study, two alternatively spliced androgen receptor(AR) variants, which are exclusively expressed in the granulosa cells of patients with polycystic ovary syndrome, exhibit retarded nuclear tra...
关键词:ANDROGEN receptor SPLICE variants nuclear TRANSLOCATION heat shock protein 90 IMPORTIN α POLYCYSTIC OVARY syndrome 
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