云南高校图书馆联盟文献共享服务平台- SPLICE

SPLICE: 作品数：39被引量：78H指数：4; 导出分析报告; 相关作者：刘莘冀肖榆张鹤顾懿李素波更多>>; 相关机构：清华大学锦州医科大学和之合股份有限公司桂林电子科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划上海市青年科技启明星计划梧州市科学研究与技术开发计划项目更多>>

虚拟仿真结合改良SPLICE教学法在医学专硕生批判性思维能力培养中的应用: 《中国医学教育技术》2025年第2期235-240,共6页王莉丽孙健; 辽宁省教育科学“十四五”规划2022年度立项课题一般课题(JG22DB276);锦州医科大学研究生教育教学研究与改革项目(YJ2024-012)。; 目的探讨虚拟仿真结合改良自我导向、问题导向、终身学习、综合临床案例练习(selfdirected,problem-oriented,lifelong learning,integrated clinical case exercise,SPLICE)教学法对临床医学专硕生批判性思维能力的影响。方法选取2024...; 关键词：虚拟仿真改良SPLICE教学批判性思维能力学业自我效能感

SNORD3B-2 promotes endometrial carcinoma progression by 2'-O-methylation modification of PLK1 and regulating RAB17 alternative splice: 《Genes & Diseases》2025年第2期90-93,共4页Xi Chen Yuping Du Bumin Xie Qianhui Li Yumeng Ji Yang Han Xiujie Sheng Shuo Chen Yang Zhao; supported by the National Natural Science Foundation of China (No.82072854 to Yang Zhao,82272985 to Shuo Chen);the Project for Key Medicine Discipline Construction of Guangzhou Municipality,Guangdong,China (No.2021-2023-17);the Science and Technology Projects in Guangzhou,Guangdong,China (No.202201020093 to Yang Zhao).; Endometrial cancer(EC)is one of the most common gynecological malignant tumors.Further investigation of the potential molecular mechanism of EC is important.Small nucleolar RNA(snoRNA)is a type of non-coding RNA,with ...; 关键词：PLK1 PI3K ENDOMETRIAL

虚拟仿真技术联合改良SPLICE教学法在皮肤科临床实践教学中的应用: 《中国医学教育技术》2025年第1期126-131,共6页王莉丽孙健; 2022年辽宁省教育科学“十四五”规划一般课题(JG22DB276);锦州医科大学研究生教育教学研究与改革项目(YJ2024-004)。; 目的应用柯氏评估模型探讨虚拟仿真技术联合改良SPLICE教学法在皮肤科临床实践教学中的应用效果。方法选取2023年3—7月在锦州医科大学附属第一医院皮肤科见习的2020级临床医学专业本科生共80名作为研究对象。采用随机分组法分为试验组(...; 关键词：虚拟仿真改良SPLICE教学皮肤科柯氏模型临床实践

基于splice-LSTM的多因素西江水位预测模型研究被引量：3: 《人民长江》2023年第7期81-88,共8页吕海峰冀肖榆丁勇; 国家自然科学基金项目(62172119);梧州市科技计划项目(2022A01036);国家级大学生创新创业训练计划立项项目(202211354015)。; 准确的水位和水量等水文时间序列预测是水资源管理的重要依据。受上游支流流量、水位等因素影响,传统的单因素水位预测模型不能有效考虑众多因素,水位预测精度面临严峻挑战。以典型西江干线梧州站水位精准预测为研究对象,建立了基于spli...; 关键词：水位预测船闸调度 splice-LSTM模型西江流域

The pentatricopeptide repeat protein EMB1270 interacts with CFM2 to splice specific group Ⅱ introns in Arabidopsis chloroplasts被引量：1: 《Journal of Integrative Plant Biology》2021年第11期1952-1966,共15页Li Zhang Jingli Chen Liqun Zhang Ying Wei Yajuan Li Xinyun Xu Hui Wu Zhong‐Nan Yang Jirong Huang Fenhong Hu Weihua Huang Yong‐Lan Cui; This study was supported by the National Natural Science Foundation of China(31100180,31470337,31570231);Shanghai Natural Science Foundation(18ZR1428200);The Fund of Innovation Program of Shanghai Municipal Education Commission(2021-01-07-00-02-E00117);Shanghai Engineering Research Center of Plant Germplasm Resources(17DZ2252700)。; Chloroplast biogenesis requires the coordinated expression of chloroplast and nuclear genes.Here, we show that EMB1270, a plastid-localized pentatricopeptide repeat(PPR) protein, is required for chloroplast biogenesis...; 关键词：Arabidopsis thaliana CRM Family Member 2 CHLOROPLAST EMB1270 intron splicing pentatricopeptide repeat protein

Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and fulllength Abelson interactor 1: 《World Journal of Gastroenterology》2021年第15期1595-1615,共21页Kun Li Yi-Fan Peng Jing-Zhu Guo Mei Li Yu Zhang Jing-Yi Chen Ting-Ru Lin Xin Yu Wei-Dong Yu; National Natural Science Foundation of China,No.30872923 and No.81672853;and Peking University People’s Hospital Scientific Research Development Found,No.RDH2020-11.; BACKGROUND Expression of the full-length isoform of Abelson interactor 1(ABI1),ABI1-p65,is increased in colorectal carcinoma(CRC)and is thought to be involved in one or more steps leading to tumor progression or metas...; 关键词：Colon cancer Abelson interactor 1 isoform-L Cell adhesion Cell migration WAVE2

Experimental seismic behavior of squat shear walls with precast concrete hollow moulds被引量：4: 《Earthquake Engineering and Engineering Vibration》2019年第4期871-886,共16页Han Wenlong Zhao Zuozhou Qian Jiaru Zhang Yingbao Ma Tao; Beijing Everest Green Building Technology Ltd. for the funding; This study proposes an innovative precast shear wall system, called an EVE precast hollow shear wall structure (EVE-PHSW). Precast panels in EVE-PHSW are simultaneously precast with vertical and horizontal holes. Nonc...; 关键词：precast concrete HOLLOW mould low-aspect-ratio NONCONTACT lap SPLICE prefabricated boundary element vertical and horizontal joints seismic behavior

CircAST:Full-length Assembly and Quantification of Alternatively Spliced Isoforms in Circular RNAs被引量：2: 《Genomics, Proteomics & Bioinformatics》2019年第5期522-534,共13页Jing Wu Yan Li Cheng Wang Yiqiang Cui Tianyi Xu Chang Wang Xiao Wang Jiahao Sha Bin Jiang Kai Wang Zhibin Hu Xuejiang Guo Xiaofeng Song; the National Natural Science Foundation of China(Grant No.61571223);the National Key R&D Program of China(Grant No.2016YFA0503300);supported by the National Natural Science Foundation of China(Grant Nos.61171191,31471403,and 81771641);the 333 Project of Jiangsu Province(Grant No.BRA2016386);the Program for Distinguished Talents of Six Domains in Jiangsu Province(Grant No.YY-019);the Fundamental Research Funds for the Central Universities(Grant No.NP2018109);the Fok Ying Tung Education Foundation(Grant No.161037),China.; Circular RNAs(circ RNAs),covalently closed continuous RNA loops,are generated from cognate linear RNAs through back splicing events,and alternative splicing events may generate different circ RNA isoforms at the same ...; 关键词：CIRCULAR RNA FULL-LENGTH reconstruction ISOFORM quantification Multiple SPLICE graph model Transcriptome

Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants被引量：5: 《Science China(Life Sciences)》2019年第2期257-267,共11页Ye Liu Yinyu Wang Fangfang Wang Jiexue Pan Jingjing Xu Jingyi Li Chengliang Zhou Guolian Ding Yanting Wu Xinmei Liu Jianzhong Sheng Hefeng Huang; supported by the National Key Research and Development Program of China (2017YFC1001303);International Cooperation Project of China and Canada NSFC (81661128010);National Natural Science Foundation of China (31471405, 81671456, 81671412);the National Key Basic Research Program (2013CB967404); the Doctoral Innovation Fund of School of Medicine, Shanghai Jiao Tong University (BXJ201640); As shown in our previous study, two alternatively spliced androgen receptor(AR) variants, which are exclusively expressed in the granulosa cells of patients with polycystic ovary syndrome, exhibit retarded nuclear tra...; 关键词：ANDROGEN receptor SPLICE variants nuclear TRANSLOCATION heat shock protein 90 IMPORTIN α POLYCYSTIC OVARY syndrome

Hepatitis B virus pre-S/S variants in liver diseases被引量：14: 《World Journal of Gastroenterology》2018年第14期1507-1520,共14页Bing-Fang Chen; Supported by the grant from the National Science Council(NSC 96-2320-B-030-004-MY3),Executive Yuan,Taiwan; Chronic hepatitis B is a global health problem. The clinical outcomes of chronic hepatitis B infection include asymptomatic carrier state, chronic hepatitis(CH), liver cirrhosis(LC), and hepatocellular carcinoma(HCC)....; 关键词：HEPATITIS B virus pre-S/S mutant pre-S DELETION SPLICE variant spPS1 chronic HEPATITIS liver cirrhosis hepatocellular carcinoma

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