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作品数：4775被引量：11566H指数：31
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相关作者：邓汉武李一乔陈忠李元建龚建光更多>>
相关机构：复旦大学南京医科大学北京大学中国科学院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Sturgeon cartilage-derived chondroitin sulfate exhibited anti-inflammatory activity against dextran sulfate sodium-induced colitis via modification of gut microbiota
《Food Science and Human Wellness》2025年第4期1239-1250,共12页Ruiyun Wu Zixin Han Zhenyu Wang Pinglan Li Nan Shang 
funded by grants from Beijing Fishery Innovation Team Project(BAIC07-2023-13);National Natural Science Foundation of China(32201994)。
Chondroitin sulfate(CS)is one of the main bioactive compounds in animal cartilage.In this study,the antiinflammatory activity of sturgeon-derived chondroitin sulfate(SCS)was evaluated in the dextran sulfate sodium(DSS...
关键词：Sturgeon cartilage Chondroitin sulfate Anti-inflammatory activity Dextran sulfate sodium-induced colitis Gut microbiota 
Tremella polysaccharide mitigates high-fat diet-induced anxiety-like behavior through the microbiota-gut-brain axis
《Food Science and Human Wellness》2025年第3期1062-1079,共18页Haicui Wu Shuyu Chen Wenxiu Zhang Yuqing Lub Jiayi Zheng Jinhui Chang Jiachi Chiou 
supported by the Seed Fund of Research Institute of Future Food(1-CD54)。
High-fat diet(HFD)consumption induces gut microbiota dysbiosis and neuropsychiatric disorders,including anxiety.Previous research found that Tremella polysaccharide(TP)exhibited neuroprotective effects in vitro and in...
关键词：Tremella polysaccharide High-fat diet Anxiety-like behavior Microbiota-gut-brain axis 
Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury
《Neural Regeneration Research》2025年第5期1416-1430,共15页Mou Gao Qin Dong Dan Zou Zhijun Yang Lili Guo Ruxiang Xu 
supported by the National Natural Science Foundation of China,Nos.82271397(to MG),82001293(to MG),82171355(to RX),81971295(to RX),and 81671189(to RX)。
Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells ...
关键词：Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell MICROGLIA NEUROINFLAMMATION 
Pegaspargase induced multiple organ failure with acute lymphoblastic leukemia:A case report
《World Journal of Clinical Cases》2025年第13期14-19,共6页Su-Xia Bao Xiao-Ling Yuan Lei Yan Jie Xu 
Supported by National Natural Science Foundation of China,No.82100625;Zhejiang Provincial natural Science Foundation of China,No.Q20H030013.
BACKGROUND The introduction of pegaspargase has greatly advanced the treatment of acute lymphoblastic leukemia(ALL).In the literature,only one case of pegaspargaseinduced multiple organ failure has been reported,and t...
关键词：PEGASPARGASE Multiple organ failure Acute lymphoblastic leukemia Liver failure Case report 
Oxaliplatin-induced diffuse alveolar hemorrhage:A case report
《World Journal of Clinical Oncology》2025年第4期343-348,共6页Toshiaki Tsurui Emiko Mura Atsushi Horiike Takuya Tsunoda 
BACKGROUND Drug-induced lung injury is a common adverse effect of chemotherapeutic agents.Diffuse alveolar hemorrhage(DAH)is a fatal complication associated with druginduced lung injury.Early diagnosis and treatment o...
关键词：Diffuse alveolar hemorrhage OXALIPLATIN Esophageal neoplasms Lung injury Drug therapy Case report 
A Deep Learning Estimation Method for Temperature-Induced Girder End Displacements of Suspension Bridges
《Structural Durability & Health Monitoring》2025年第2期307-325,共19页Yao Jin Yuan Ren Chong-Yuan Guo Chong Li Zhao-Yuan Guo Xiang Xu 
The National Key Research and Development Program of China grant No.2022YFB3706704 received by Yuan Ren;the National Natural and Science Foundation of China grant No.52308150 received by Xiang Xu.
To improve the accuracy of thermal response estimation and overcome the limitations of the linear regression model and Artificial Neural Network(ANN)model,this study introduces a deep learning estimation method specif...
关键词：Suspension bridges thermal response girder end displacement deep learning 
Therapeutic potential of the citrus flavonoid hesperidin and its aglycone hesperetin against chemotherapy-induced toxicity
《Traditional Medicine Research》2025年第4期31-48,共18页Yu-Su Wang Wei-Jian Chen Zi-Yao Mo Yun-Jing He Ke Nie 
Innovative Team Project of Ordinary Universities in Guangdong Province(No.2022KCXTD016).
Chemotherapy-induced toxicity(CIT)remains a major concern in cancer patients undergoing chemotherapy.New approaches to ameliorate the side effects of chemotherapy are urgently needed.Recently,the nutritional value of ...
关键词：chemotherapy-induced toxicity citrus flavonoids HESPERIDIN HESPERETIN 
Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation
《Genes & Diseases》2025年第2期414-424,共11页Ye Zhu Xuehuan Meng Qiming Zhai Liangjing Xin Hao Tan Xinyi He Xiang Li Guoyin Yang Jinlin Song Leilei Zheng 
supported by the Natural Science Foundation of China (No.82471016,81470772);Chongqing Talent Program:Innovative Leading Talents (Medical Field,No.CQYC20210303384);Chongqing Medical Scientific Research Project (China) (No.cstc2020jcyj-msxmX0307);Youth Innovation in Future Medicine (Chongqing Medical University) (No.W0033).
Orthodontic tooth movement(OTM)depends on periodontal ligament cells(PDLCs),which sense biomechanical stimuli and initiate alveolar bone remodeling.Light(optimal)forces accelerate OTM,whereas heavy forces decelerate i...
关键词：BIOMECHANICS Bone remodeling/regeneration MECHANO-TRANSDUCTION Orthodontic tooth movement Periodontal ligament 
Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per-and polyfluoroalkyl substances
《Journal of Environmental Sciences》2025年第4期395-411,共17页Yanping Li Yadan Luo Yang Liu Na Li Kai Huang Lingxiangyu Li Zhigang Li Chao Han Nali Zhu Yawei Wang Guibin Jiang 
supported by the Key Research and Development Plan of Zhejiang Province(No.2021C03176);Zhejiang Provincial Natural Science Foundation of China(No.LY23B070001);the Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province(No.20230009);the National Natural Science Foundation of China(No.22106032);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0750000).
Per-and polyfluoroalkyl substances(PFASs)can induce a range of adverse health effects,with the precise molecularmechanisms remaining elusive.Extracellular vesicles(EVs)have demonstrated their potential to elucidate un...
关键词：Per-and polyfluoroalkyl substances Extracellular vesicles Health effects PROTEOMICS PROTEASOME 
Furmonertinib re-challenge for epidermal growth factor receptormutant lung adenocarcinoma after osimertinib-induced interstitial lung disease:A case report
《World Journal of Clinical Oncology》2025年第3期142-150,共9页Fei-Fei Wei Jing Zhang Zhe Jia Zhi-Chao Yao Chun-Qiao Chen 
Supported by Guangxi Guilin Science and Technology Fund,No.20190218-7-6.
BACKGROUND Most non-small cell lung cancer patients have epidermal growth factor receptor(EGFR)activating mutations,such as exon 19 deletion and exon 21 replacement mutations.Osimertinib is a third-generation EGFR-tyr...
关键词：Furmonertinib Osimertinib Lung adenocarcinoma Interstitial lung disease Case report 
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