LONG-TERM

作品数：1222被引量：3113H指数：22
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Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregulation in dopaminergic neurons被引量：5
《Neural Regeneration Research》2020年第4期712-723,共12页Yun-Cheng Lv An-Bo Gao Jing Yang Li-Yuan Zhong Bo Jia Shu-Hui Ouyang Le Gui Tian-Hong Peng Sha Sun Francisco S.Cayabyab 
supported by the National Natural Sciences Foundation of China,No.81770460(to YCL);the Postdoctoral Research Fellowship of the Saskatchewan Health Research Foundation,No.SHRF,4144(to YCL);the third level of the Chuanshan Talent project of the University of South China,No.2017CST20(to YCL);the Aid Program,No.2017KJ268 and the Key Lab for Clinical Anatomy&Reproductive Medicine,No.2017KJ182 from the Science and Technology Bureau of Hengyang City,China(to YCL and XC);the Postgraduate Student Research Innovation Projects of Hunan Province,China,No.CX2018B62(to ABG)
Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative diseases.However,the pathogenesis underlying long-term adenosine A1 receptor...
关键词：cognitive dysfunction DOPAMINERGIC neuron DYSKINESIA JNK/c-JUN pathway LONG-TERM adenosine A1 receptor activation neural regeneration NEURODEGENERATIVE diseases SORTILIN Α-SYNUCLEIN 
GLYX-13 pretreatment ameliorates long-term isoflurane exposure-induced cognitive impairment in mice被引量：4
《Neural Regeneration Research》2020年第1期128-135,共8页Huan Liu Xiang-Dan Gong Xin Zhao Yue Qian Xiao-Ping Gu Tian-Jiao Xia 
supported by the National Natural Science Foundation of China,No.81730033(to XPG),81701371(to TJX),81801380(to XZ);Natural Science Foundation of Jiangsu Province of China,No.BK20170654(to TJX),BK20170129(to XZ)
Accumulating evidence indicates that inhalation anesthetics induce or increase the risk of cognitive impairment. GLYX-13（rapastinel） acts on the glycine site of N-methyl-D-aspartate receptors（NMDARs） and has been ...
关键词：Ca2+/calmodulin-dependent protein kinase II cognitive impairment contextual fear conditioning cyclic adenosine monophosphate response element binding protein GLYX-13 ISOFLURANE N-methyl-D-aspartate receptor novel object recognition rapastinel 
Can long-term thiamine treatment improve the clinical outcomes of myotonic dystrophy type 1？被引量：1
《Neural Regeneration Research》2016年第9期1487-1491,共5页Antonio Costantini Erika Trevi Maria Immacolata Pala Roberto Fancellu 
Myotonic dystrophy type 1, also known as Steinert＇s disease, is an autosomal dominant disorder with multisystemic clinical features affecting the skeletal and cardiac muscles, the eyes, and the endocrine system. Thia...
关键词：nerve regeneration myotonic dystrophy type I THIAMINE Steinert＇s disease muscular strength activity of daily living neural regeneration 
Comparison of short- with long-term regeneration results after digital nerve reconstruction with musclein-vein conduits
《Neural Regeneration Research》2015年第10期1674-1677,共4页Jennifer Lynn Schiefer Lukas Schulz Rebekka Rath Stéphane Stahl Hans-Eberhard Schaller Theodora Manoli 
Muscle-in-vein conduits are used alternatively to nerve grafts for bridging nerve defects. The purpose of this study was to examine short- and long-term regeneration results after digital nerve reconstruction with mus...
关键词：peripheral nerve regeneration muscle-in-vein conduits digital nerves sensory recovery Semmes-Weinstein two-point discrimination outcome short-term long-term 
Effects of long-term sustained naltrexone release on the optic center in opioid-dependent patients Case-control study in four provinces of China
《Neural Regeneration Research》2011年第3期236-240,共5页He, Shengxi Yu, Longchuan Jia, Shaowei Chen, Qing Wang, Dongmei Hu, Shu 
the Natural Science Foundation of Guangdong Province,No. 06027973;the Science and Technology Development Program of Guangdong Province,No. 2004B3600105;the Medical Science Foundation Program of Guangdong Province,No. A2007592
Very little is known about visual functional recovery following long-term naltrexone administration in opioid-dependent patients. In the present study, a portable event-related potential （ERP） working system was uti...
关键词：long-term sustained naltrexone release opioid dependence projection of unilateralvisual field event-related potential PIO0 
Repair of abnormal perfusion foci in idiopathic epilepsy patients under long-term antiepileptic treatment被引量：7
《Neural Regeneration Research》2011年第2期155-160,共6页Weimin Wang Siyu Zhao Yaqing Liu 
the Key Pro-ject of Gansu Province,No. 432328
Epileptic seizure control and the disappearance of epileptJform discharge are not indicative of the absence of abnormal perfusion foci. Perfusion abnormalities are a major cause of epileptic discharge, and the existen...
关键词：abnormal perfusion focus brain damage idiopathic epilepsy neural regeneration region of interest REPAIR single-photon emission computed tomography 
Case report of a healthy,elderly man with long-term high titers for anti-acetylcholine receptor antibody without myasthenia gravis
《Neural Regeneration Research》2010年第23期1832-1835,共4页Jin Jun LUO Nae J. Dun 
Anti-acetylcholine receptor antibodies （AAR） are considered pathognomonic and pathogenetic for myasthenia gravis （MG）. AAR detection confirms clinical diagnosis of MG. However, AAR is rarely detected in patients w...
关键词：myasthenia gravis anti-acetylcholine receptor antibody false-positive antibody autoimmune disorder 
Zinc transporter-3 expression and long-term cognitive impairments in a rat model of neonatal concurrent seizure
《Neural Regeneration Research》2009年第8期618-622,共5页Hong Ni Yuwu Jiang Luyang Tao Zhenghong Qin Xiru Wu 
the National Natural Science Foundation of China,No.30470555, 30870808;the Natural Science Foundation of Jiangsu Province of China, No.BK2007509;the Natural Science Foundation for Higher Education Institutions in Jiangsu Province, No.07KJB320103
BACKGROUND： Developmental seizures, which are pathologically characterized by regenerative sprouting of hippocampal mossy fibers, cause long-term damaging effects to synaptic plasticity. Zn^2＋ metabolism has been sh...
关键词：zinc transporter-3 neonatal seizure Morris water maze learning MEMORY 
Short-term versus long-term water maze training effects on hippocampal neuronal synaptic plasticity in a rat model of senile dementia被引量：1
《Neural Regeneration Research》2008年第9期929-932,共4页Guogui Li 
the Natural Science Foundation of Hubei Province, No.2005ABA197
BACKGROUND： Changes in synaptic plasticity might underlie senile dementia, and might be the neurobiological basis for learning and memory dysfunctions in patients with Alzheimer＇s Disease. OBJECTIVE： To investigate...
关键词：Alzheimer＇s disease HIPPOCAMPUS memory model PLASTICITY rats SYNAPSE 
Value of long-term electroencephalogram in diagnosing epilepsy被引量：1
《Neural Regeneration Research》2007年第9期544-547,共4页Shisen Zhang 
BACKGROUND： Routine electroencephalogram （EEG） usually cannot accurately reflect the discharge of epileptic patients due to the short examination, and long-term EEG can make up the shortcoming. OBJECTIVE： To compa...
关键词：ELECTROENCEPHALOGRAPHY EPILEPSY SLEEP 
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