云南高校图书馆联盟文献共享服务平台- MASH

MASH: 作品数：92被引量：356H指数：9; 导出分析报告; 相关领域：电子电信天文地球更多>>; 相关作者：丁欣李红吴建辉许春艳邹家禄更多>>; 相关机构：东南大学中国科学院中国地质大学（北京）中国科学院大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国地质调查局地质调查项目更多>>

How improvements in US FDA regulatory process and procedures led to the drug approval for first ever treatment of a common liver disease: 《Acta Pharmacologica Sinica》2025年第3期515-524,共10页Brian E.Harvey; Metabolic-associated liver disease is a growing public health crisis,with phenotypes from fatty liver to steatohepatitis,previously known as NASH(Non-Alcoholic SteatoHepatitis)and currently rebranded as MASH(Metabolic...; 关键词：US Food&Drug Administration metabolic dysfunction-associated steatohepatitis MASH NASH type 2 diabetes mellitus DYSLIPIDEMIA

Drug discovery targeting thyroid hormone receptor b (THRb) for the treatment of liver diseases and other medical indications: 《Acta Pharmaceutica Sinica B》2025年第1期35-51,共17页Kean Wang Feiyang Chen Jiang Wang Hong Liu; the National Natural Science Foundation of China(82130105,22337003,and 82121005 to Hong Liu,and 82322063,22177124 to Jiang Wang);the Lingang Laboratory(LG-GG-202403-01 to Jiang Wang,China);Program of Shanghai Academic Research Leader(23XD1460300 to Jiang Wang,China).; Thyroid hormone receptors(THRs),a crucial nuclear receptor protein family,primarily consist of two categories:a receptors and b receptors.Among them,THRb is the primary subtype of thyroid hormone that confers benefits...; 关键词：Thyroid hormone Thyroid hormoneβreceptor MASLD MASH THRβagonist

Resmetirom for metabolic dysfunction-associated steatohepatitis:targeting hepatic and cardiovascular disease: 《Hepatobiliary Surgery and Nutrition》2024年第6期1034-1037,共4页Isabella Lurje Frank Tacke; Metabolic dysfunction-associated steatotic liver disease(MASLD)is defined as hepatic steatosis with at least one concomitant cardiovascular risk factor,and has emerged as the most frequent liver disease worldwide(1).I...; 关键词：Metabolic dysfunction-associated steatotic liver disease(MASLD) metabolic dysfunctionassociated steatohepatitis(MASH) nonalcoholic fatty liver disease(NAFLD) nonalcoholic steatohepatitis(NASH) thyroid receptors

FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis: 《Acta Pharmacologica Sinica》2024年第11期2313-2327,共15页Ying-quan Wen Zi-yuan Zou Guan-guan Zhao Meng-jiao Zhang Yong-xin Zhang Gai-hong Wang Jing-jing Shi Yuan-yang Wang Ye-yu Song Hui-xia Wang Ru-ye Chen Dong-xuan Zheng Xiao-qun Duan Ya-meng Liu Frank J.Gonzalez Jian-gao Fan Cen Xie; supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39020600);National Key Research and Development Program of China(2021YFA1301200);National Natural Science Foundation of China(82222071,91957116,82173873);and Project supported by Shanghai Municipal Science and Technology Major Project.; The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis(MASH)to the forefront of public health concerns.The activation of FXR shows promise to combat MASH a...; 关键词：MASLD/MASH FXR TRANSCRIPTOME gut-liver axis AGONIST

应用于WIFI收发系统的宽带低杂散频率综合器设计: 《中国集成电路》2024年第11期55-62,共8页廖春连李斌曲明宋明宇; 本文基于28nm标准CMOS工艺,提出一种适用于WIFI收发系统的频率综合器,该频率综合器电路包括鉴频鉴相器、电荷泵、宽带压控振荡器、可编程分频器和HK-MASH小数调制器。与常规的MASH结构相比,HK-MASH结构具有更好的降杂散能力。经过测试,...; 关键词：HK-MASH 宽带压控振荡器频率综合器

Potential therapeutic strategies for MASH: from preclinical to clinical development: 《Life Metabolism》2024年第5期45-60,共16页Zhifu Xie Yufeng Li Long Cheng Yidan Huang Wanglin Rao Honglu Shi Jingya Li; supported by grants from the National Natural Science Foundation of China(92057116 to J.L.;82170872 to Z.X.,and 82200965 to Y.L.);the Natural Science Foundation of Shanghai’s 2021“Science and Technology Innovation Action Plan”(21ZR1475300 to Z.X.);Shanghai Science and Technology Development Funds(22YF1456900 to Y.L.).; Current treatment paradigms for metabolic dysfunction-associated steatohepatitis(MASH)are based primarily on dietary restrictions and the use of existing drugs,including anti-diabetic and anti-obesity medications.Give...; 关键词：STEATOSIS inflammation FIBROSIS metabolic dysfunction-associated steatohepatitis PHARMACOTHERAPY

Brand Construction of Characteristic Agricultural Products in Ethnic Regions under the Background of Rural Revitalization:A Case Study of Honeysuckle Industry of Mashan County被引量：1: 《Meteorological and Environmental Research》2024年第4期66-70,共5页Shaohong MO; The brand construction of agricultural products is a necessary path for agricultural development and an effective way to enhance the added value and market competitiveness of agricultural products.How to do a good job...; 关键词：Rural revitalization Local specialty agricultural products Brand construction HONEYSUCKLE

采用Mash2-1架构的高精度Sigma-Delta ADC设计: 《微处理机》2024年第3期22-25,共4页于凯至辛晓宁任建卢苡; 鉴于模数转换器(ADC)在芯片和混合信号处理领域举足轻重的作用,为探索进一步提高模数转换器精度的可能性,满足当今应用系统对模数转换精度的新需求,设计一款基于Mash2-1级联架构的sigma-delta ADC。设计采用TSMC 180 nm CMOS工艺,在完...; 关键词：SIGMA-DELTA调制器高信噪比低失真 Mash级联架构

三峡水库蓄水20年以来宜昌水文站水文情势改变分析被引量：1: 《长江科学院院报》2024年第6期193-199,206,共8页朱迪崔福宁卜慧汪琳王含; 水利部重大科技项目(SKS-2022038);国家重点研发计划项目(2021YFC3200304)。; 三峡水库自2003年开展蓄水调度以来,已运行20 a,在防洪、发电、航运、水资源利用、生态环境保护等方面发挥了重要作用,但也对下游水文情势产生影响。选择宜昌水文站1950—2022年逐日径流和水位资料,采用MASH滑动平均法、Sen斜率估计法和...; 关键词：三峡水库水文情势 MASH滑动平均法 IHA/RVA法宜昌水文站

Hormone-based pharmacotherapy for metabolic dysfunction-associated fatty liver disease被引量：1: 《Medical Review》2024年第2期158-168,共11页Zara Siu Wa Chui Yaqian Xue Aimin Xu; supported by National Key R&D Program of China(2022YFA0806102);the Hong Kong Research Grants Council/Area of Excellence(AoE/M-707/18);Health and Medical Research Fund(06172446);General Research Fund(17127518);as well as the National Natural Science Foundation of China(82070860,82161138026).; Metabolic dysfunction-associated fatty liver disease(MAFLD)has reached epidemic proportions globally in parallel to the rising prevalence of obesity.Despite its significant burden,there is no approved pharmacotherapy ...; 关键词：metabolic hormones metabolic dysfunctionassociated steatohepatitis(MASH) liver fibrosis biopharmaceutical development clinical trials

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

MASH

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

MASH

检索结果分析

下载全文

用户登录

高级检索检索式检索