the grants from the National Natural Science Foundation of China(Nos.81773294,81472608 and 31200573);the project of Education Department of Hunan Province(Nos.16A189 and 15C1204);the Natural Science Foundation of Hunan Province(No.13JJ6051);the Chuanshan Talent Project of the University of South China(No.CS2018-3-35).
Autophagy as a novel therapeutic target can inhibit or increase treatment efficacy in various types of breast cancer in a cell-type-dependent manner [1,2].Several studies have revealed that the coordination between Ak...
This work was supported by the National Natural Science Foundation of China (31401186, 81473249, 81321004 and 81673471), National Mega-project for Innovative Drugs (2014ZX09201042) and the CAMS Innovation Fund for Medical Sciences (CIFMS) (2016-I2M-2-002).
c-Myc, a key activator of cell proliferation and angiogenesis, promotes the development and progression of breast cancer. Ezrin-radixin-moesin-binding phosphoprotein-50 (EBPSO) is a multifunctional scaffold protein ...
Owing to the presence of multidrug resistance in tumor cells, conventional chemotherapy remains clinically intractable. To enhance the therapeutic efficacy of chemotherapeutic agents, targeting strategies based on mag...
This research was supported by National Natural Science Foundation of China (No 81273517).
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in regulating cell survival and death. Silibinin is a natural polyphenolic flavonoid isolated from milk thistle with anti-tumo...