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Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration
《Neural Regeneration Research》2026年第1期406-416,共11页Xiaoxu Huang Yumeng Zhang Yuxin Jiang Tong Li Shiqi Yang Yimin Wang Bo Yu Minwen Zhou Guanran Zhang Xiaohuan Zhao Junran Sun Xiaodong Sun 
supported by the National Natural Science Foundation of China,Nos. 82171076 (to XS) and U22A20311 (to XS), 82101168 (to TL);Shanghai Science and technology Innovation Action Plan,No. 23Y11901300 (to JS);Science and Technology Commission of Shanghai Municipality,No. 21ZR1451500 (to TL);Shanghai Pujiang Program,No. 22PJ1412200 (to BY)。
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal de...
关键词:age-related macular degeneration ferroptosis light exposure damage oxidative stress pathway PHOTORECEPTOR programmed cell death solute carrier family 7 member 11(SLC7A11) 
Working Together for Inter-Civilizational Exchange and Mutual Learning
《China Today》2025年第5期32-36,共5页JIA GUIDE 
Italy is a key member of the EU,and the China-Italy relationship is an important aspect of the China-EU relationship.
关键词:mutual learning eu member china italy relationship inter civilizational exchange china eu relationship 
Clinical,genetic and functional perspectives on ATP-binding cassette subfamily B member 4 variants in five cholestasis adults
《World Journal of Gastroenterology》2025年第14期142-156,共15页Yu-Hang Weng Yu-Feng Zheng Dan-Dan Yin Qing-Fang Xiong Jin-Long Li Shun-Xin Li Wei Chen Yong-Feng Yang 
Supported by the National Natural Science Foundation of China,No.81970454.
BACKGROUND ATP-binding cassette subfamily B member 4(ABCB4)deficiency is associated with cholestatic liver disease primarily because of missense mutations,and many variants remain unidentified.Here,we validate the pat...
关键词:ATP-binding cassette subfamily B member 4 Multidrug resistance protein 3 CHOLESTASIS Functional analysis CLINICAL Gene mutation Whole-exome sequencing 
MdBAM17, a novel member of the β-amylase gene family,positively regulates starch degradation in ALA-induced stomatal opening in apple
《Horticultural Plant Journal》2025年第2期504-519,共16页Longbo Liu Jiayi Zhou Jianting Zhang Yan Zhong Liangju Wang 
supported by the Natural Science Foundation of China(Grant No.32172512);the Jiangsu Special Fund for Frontier Foundation Research of Carbon Peaking and Carbon Neutralization(Grant No.BK20220005);a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions。
5-Aminolevulinic acid(ALA)is a novel plant growth regulator that has shown outstanding capability to promote stomatal opening.Starch degradation,catalyzed byβ-amylase(EC3.2.1.2,BAM),plays an important role in stomata...
关键词:ALA APPLE BAM gene family MdBAM17 Starch degradation Stomatal opening 
LncRNA FTX promotes colorectal cancer radioresistance through disturbing redox balance and inhibiting ferroptosis via miR-625-5p/SCL7A11 axis
《World Journal of Gastroenterology》2025年第16期49-65,共17页Qing Dai Tian-Yin Qu Jin-Lan Yang Jing Leng Lin Fang Qian-Qian Zhu Ke-Bi Wu Jie Wu Jing-Jing Ma Huang-Fei Yu 
Supported by the National Natural Science Foundation of China,No.81960506;Science and Technology Fund Project of Guizhou Provincial Health Commission,No.gzwkj2022-299;Key Projects of Zunyi Science and Technology Fund,No.zunshikeheHZzi(2023)24 and No.zunshikeheHZzi(2024)9.
BACKGROUND Radiotherapy is widely employed in colorectal cancer(CRC)treatment,but the occurrence of radioresistance severely limits the clinical benefit to patients and significantly contributes to treatment failure a...
关键词:Colorectal cancer LncRNA FTX Solute carrier family 7 member 11 Ferroptosis Redox RADIORESISTANCE 
Inhibition of the SERPINB5/HSP90AA1 axis restrains the proliferation and invasion of rectal cancer
《World Journal of Gastroenterology》2025年第11期153-163,共11页Ze-Song Meng Ji-Tao Hu Hao Wu Bao-Kun Li 
Supported by the Medical Science Research Project Plan of the Hebei Provincial Health Commission,No.20210027.
BACKGROUND The upregulation of serpin family B member 5(SERPINB5)has been linked to the progression of rectal cancer.However,the specific roles and underlying mechanisms of SERPINB5 in rectal cancer are not fully unde...
关键词:Rectal cancer Serpin family B member 5 Heat shock protein 90 alpha class A member 1 PROLIFERATION INVASION 
NR4A1 silencing alleviates high-glucose-stimulated HK-2 cells pyroptosis and fibrosis via hindering NLRP3 activation and PI3K/AKT pathway
《World Journal of Diabetes》2025年第3期203-215,共13页Jin-Meng Li Zi-Hua Song Yuan Li Han-Wen Chen Han Li Lu Yuan Jing Li Wen-Yue Lv Lei Liu Na Wang 
Supported by Research Fund for Academician Lin He New Medicine,No.JYHL2022FMS02.
BACKGROUND The pathophysiology of diabetic kidney disease(DKD)is complex.Interfering with the processes of pyroptosis and fibrosis is an effective strategy for slowing DKD progression.Previous studies have revealed th...
关键词:Diabetes Diabetic kidney disease PYROPTOSIS FIBROSIS Nuclear receptor subfamily 4 group A member 1 
High-speed Railway Young Ed itoral Board Member
《High-Speed Railway》2025年第1期F0003-F0003,共1页
Chlorogenic acid induces hepatocellular carcinoma cell ferroptosis via PTGS2/AKR1C3/GPX4 axis-mediated reprogramming of arachidonic acid metabolism
《World Journal of Gastrointestinal Oncology》2025年第3期202-220,共19页Ling Wu Hong-Yao Chen Jing-Ting Zhang Ren-Yi Yang Zhi-Bin Wang Pei-Sen Xue Wei Peng Ke-Xiong Li Wen-Hui Gao Pu-Hua Zeng 
the National Natural Science Foundation of China,No.82074425;Natural Foundation of Hunan Province,No.2023JJ30364 and No.2023JJ30361;Hunan Provincial Key R&D Program,No.2023SK2057;Key Project of Hunan Provincial Administration of Traditional Chinese Medicine,No.A2023042.
BACKGROUND Ferroptosis is an iron-dependent programmed non-apoptotic cell death characterized by the accumulation of free iron ions and lipid peroxidation.It is associated with the inactivation of glutathione peroxida...
关键词:Chlorogenic acid Hepatocellular carcinoma Ferroptosis Prostaglandin endoperoxide synthase 2/aldo-keto reductase family 1 member C3/glutathione peroxidase 4 axis BIOINFORMATICS In vitro experiment 
MEMBER LIST OF THE SECOND EDITORIAL BOARD OF CHRONIC DISEASES AND TRANSLATIONAL MEDICINE
《Chronic Diseases and Translational Medicine》2025年第1期F0002-F0002,共1页
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