MODELING

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Adeno-associated viral vectors for modeling Parkinson's disease in non-human primates
《Neural Regeneration Research》2026年第1期224-232,共9页Julia Chocarro JoséL.Lanciego 
supported by grants PID2020-120308RB-I00 and PID2023-147802OB-I00 funded by MICIU/AEI/10.13039/501100011033;FEDER,UE,by Aligning Science Across Parkinson’s(ref.ASAP-020505)through the Michael J.Fox Foundation for Parkinson’s Research;by CiberNed Intramural Collaborative Projects(ref.PI2020/09);by the Spanish Fundación Mutua Madrile?a de Investigación Médica(to JLL)。
The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that...
关键词：adeno-associated viral vectors ALPHA-SYNUCLEIN DOPAMINE Lewy bodies NEURODEGENERATION NEUROMELANIN NEUROPATHOLOGY substantia nigra 
Modeling and Performance Evaluation of Streaming Data Processing System in IoT Architecture
《Computers, Materials & Continua》2025年第5期2573-2598,共26页Feng Zhu Kailin Wu Jie Ding 
funded by the Joint Project of Industry-University-Research of Jiangsu Province(Grant:BY20231146).
With the widespread application of Internet of Things(IoT)technology,the processing of massive realtime streaming data poses significant challenges to the computational and data-processing capabilities of systems.Alth...
关键词：System modeling performance evaluation streaming data process IoT system PEPA 
Kolmogorov-Arnold networks modeling of wall pressure wavenumber-frequency spectra under turbulent boundary layers
《Theoretical & Applied Mechanics Letters》2025年第2期115-121,共7页Zhiteng Zhou Yi Liu Shizhao Wang Guowei He 
supported by the National Natural Science Foundation of China Basic Science Center Program for“Multiscale Problems in Nonlinear Mechanics”(Grant No.11988102);the National Natural Science Foundation of China(Grant Nos.92252203,12102439,and 12425207);the Chinese Academy of Sciences Project for Young Scientists in Basic Research(Grant No.YSBR-087);the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB0620102).
The empirical models for wavenumber-frequency spectra of wall pressure are broadly used in the fast prediction of aerodynamic and hydrodynamic noise.However,it needs to fit the parameter using massive data and is only...
关键词：Wavenumber-frequency spectra Kolmogorov-Arnold networks modeling Turbulent boundary layers 
Fine-Grained Point Cloud Intensity Correction Modeling Method Based on Mobile Laser Scanning
《Computers, Materials & Continua》2025年第4期575-593,共19页Xu Liu Qiujie Li Youlin Xu Musaed Alhussein Khursheed Aurangzeb Fa Zhu 
supported in part by the National Natural Science Foundation of China under grant number 31901239;funded by Researchers Supporting Project Number(RSPD2025R947),King Saud University,Riyadh,Saudi Arabia.
The correction of Light Detection and Ranging(LiDAR)intensity data is of great significance for enhancing its application value.However,traditional intensity correction methods based on Terrestrial Laser Scanning(TLS)...
关键词：LIDAR intensity correction mobile laser scanning distance and incidence angle MODELING 
MITM: A new Mars Ionosphere-Thermosphere Model
《Earth and Planetary Physics》2025年第2期337-345,共9页ZhiPeng Ren YunBo Liu WeiXing Wan Yong Wei XinAn Yue 
This work is supported by the B-type Strategic Priority Program of the Chinese Academy of Sciences (Grant No. XDB4100000);the pre-research Project on Civil Aerospace Technologies No. D020105 funded by CNSA;the Strategic Priority Research Program of Chinese Academy of Sciences (Grant XDA17010404, XDA17010201)。
In this study, we present an innovative Mars Ionosphere-Thermosphere Model(MITM), which is a time-dependent, threedimensional(3-D) model that comprehensively represents the self-consistently coupled thermosphere and i...
关键词：MARS THERMOSPHERE IONOSPHERE MODELING 
Prediction by simulation in plant breeding
《The Crop Journal》2025年第2期501-509,共9页Huihui Li Luyan Zhang Shang Gao Jiankang Wang 
supported by Biological Breeding-National Science and Technology Major Project(2023ZD0407501);National Natural Science Foundation of China(31861143003);Innovation Program of Chinese Academy of Agricultural Sciences.
Computer simulation permits answering theoretical and applied questions in animal and plant breeding.Blib is a novel multi-module simulation platform,which is able to handle more complicated genetic effects and models...
关键词：Prediction by simulation Plant breeding MODELING Genetic model Breeding method 
An origami-inspired nonlinear energy sink:design,modeling,and analysis
《Applied Mathematics and Mechanics(English Edition)》2025年第4期601-616,共16页Youcheng ZENG Hu DING J.C.JI 
Project supported by the National Science Fund for Distinguished Young Scholars(No.12025204);the China Scholarship Council(No.202206890066)。
Designing,modeling,and analyzing novel nonlinear elastic elements for the nonlinear energy sink(NES)have long been an attractive research topic.Since gravity is difficult to overcome,previous NES research mainly focus...
关键词：nonlinear energy sink(NES) stacked Miura-origami(SMO) vertical vibration quasi-zero stiffness(QZS) 
Nonlinear stress analysis of aero-engine pipeline based on semi-analytical method
《Applied Mathematics and Mechanics(English Edition)》2025年第3期521-538,共18页Weijiao CHEN Xiaochi QU Ruixin ZHANG Xumin GUO Hui MA Bangchun WEN 
Project supported by the National Science and Technology Major Project(No.J2019-I-0008-0008);the National Natural Science Foundation of China(No.52305096);the Chinese Postdoctoral Science Foundation(No.GZB20230117)。
Fatigue failure caused by vibration is the most common type of pipeline failure.The core of this research is to obtain the nonlinear dynamic stress of a pipeline system accurately and efficiently,a topic that needs to...
关键词：pipeline modeling stress analysis nonlinear-clamp support nonlinear vibration 
Modeling telomere shortening process
《Quantitative Biology》2025年第1期77-87,共11页Panpan Han Yang Zhou Weihua Deng 
National Natural Science Foundation of China,Grant/Award Numbers:12225107,12071195;Major Science and Technology Projects in Gansu Province-Leading Talents in Science and Technology,Grant/Award Number:23ZDKA0005;Innovative Groups of Basic Research in Gansu Province,Grant/Award Number:22JR5RA391;Lanzhou Talent Work Special Fund。
Cell senescence has attracted much attention in the long history of human beings,and telomere shortening(TS)is one of the main concerns in the study of cell senescence.To reveal the microscopic mechanism of TS process...
关键词：AGING anomalous diffusion CTRW telomere shortening process 
Optimal Location of Renewable Energy Generators in Transmission and Distribution System of Deregulated Power Sector:A Review
《Energy Engineering》2025年第3期823-859,共37页Digambar Singh Najat Elgeberi Mohammad Aljaidi Ramesh Kumar Rabia Emhamed Al Mamlook Manish Kumar Singla 
The literature on multi-attribute optimization for renewable energy source(RES)placement in deregulated power markets is extensive and diverse in methodology.This study focuses on the most relevant publications direct...
关键词：Optimization of RESs distributed generation modeling and selection of RESs hybrid systems standalone systems optimal location 
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