MOLECULE-1

作品数：63被引量：347H指数：10
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相关领域：医药卫生更多>>
相关作者：张文岚杨璐薛丽娟赵军叶青更多>>
相关机构：郑州大学第五附属医院佛山市高明区人民医院吉林省中医药科学院天津市第三中心医院更多>>
相关期刊：《临床肝胆病杂志》《Journal of US-China Medical Science》《Journal of Hainan Medical University》《Current Medical Science》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金国家高技术研究发展计划更多>>
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TL1A Promotes Fibrogenesis in Colonic Fibroblasts via the TGF-β1/Smad3 Signaling Pathway
《Current Medical Science》2024年第3期519-528,共10页Jia SONG Dong-lei SUN Chen-yang LI Yu-xin LUO Qian LIU Yue YAO Hong ZHANG Ting-ting YANG Mei SONG Xin-li BAI Xiao-lan ZHANG 
supported by grants from the National Natural Science Foundation of China(No.82270545 and No.81870381);Natural Science Foundation of Hebei Province(No.H2014206446)。
Objective Intestinal fibrosis is a refractory complication of inflammatory bowel disease(IBD).Tumor necrosis factor ligand-related molecule-1A(TL1A)is important for IBD-related intestinal fibrosis in a dextran sodium ...
关键词：tumor necrosis factor ligand-related molecule-1A fibrosis inflammatory bowel disease MYOFIBROBLASTS transforming growth factor-β1 
Vitamin D deficiency and increased inflammatory factor intercellular cell adhesion molecule-1 indicate severe leukoaraiosis in northern China
《Frigid Zone Medicine》2024年第2期102-109,共8页Jiaxin Guan Lu Gan Chaoqi Yan Boyu Hou Ying Fan 
This work was supported by the National Natural Science Foundation of Heilongjiang Province of China(No.LH2020H051);Key R&D projects of Natural Science Foundation of Heilongjiang Province(No.2023ZX06C03);Foundation of Harbin Science Technology Bureau of China(No.2014RFQGJ042).
Background and objective:Commonly plaguing in the frigid zone of the world,vitamin D deficiency,as indicated by low levels of 25-hydroxyvitamin D,exacerbated inflammatory responses and impaired endothelial function.Le...
关键词：cerebral small vascular disease degenerative disease LEUKOARAIOSIS white matter hyperintensities lacunar infarction 25-hydroxyvitamin D ICAM-1 fibrinogen-C inflammatory factor fazekas scale 
Inflammation responsive tofacitinib loaded albumin nanomedicine for targeted synergistic therapy in ulcerative colitis被引量：1
《Nano Research》2023年第7期9873-9884,共12页Bang Li Xiaoyan Liu Qi Long Xiaoduan Zhuang Yanfei Gao Barkat Ali Haoting Chen Dongyang Zhang Xinying Wang Weisheng Guo 
This work was partially supported by grants from the National Natural Science Foundation of China(Nos.31971302 and 82170532);the Natural Science Foundation of Guangdong Province of China(No.2019A1515011597);the talent young scientist supporting program of China Association for Science and Technology,the Educational Commission of Guangdong Province of China key Project(No.2020ZDZX2001);the joint grant between Guangzhou City and College(No.202102010106);Guangzhou Science and Technology Plan Project(No.202201011509).
Patients with ulcerative colitis(UC)often loss responses over long term usage of conventional therapies.Tofacitinib,a pan-Janus kinases(JAK)inhibitor is approved for moderate to severe UC treatment,while dose-limiting...
关键词：ulcerative colitis mucosal vascular addressin cell-adhesion molecule-1(MAdCAM-1) tofacitinib reactive oxygen species(ROS)-responsive targeted delivery 
Temporal alterations in pericytes at the acute phase of ischemia/reperfusion in the mouse brain被引量：5
《Neural Regeneration Research》2022年第10期2247-2252,共6页Shuang Zhang Xue-Jing Liao Jia Wang Yi Shen Han-Fen Shi Yan Zou Chong-Yang Ma Xue-Qian Wang Qing-Guo Wang Xu Wang Ming-Yang Xu Fa-Feng Cheng Wan-Zhu Bai 
financially supported by the China Academy of Chinese Medical Sciences Innovation Fund,No.CI2021A03407(to WZB);the National Natural Science Foundation of China,No.81973789(to FFC).
Pericytes,as the mural cells surrounding the microvasculature,play a critical role in the regulation of microcirculation;however,how these cells respond to ischemic stroke remains unclear.To determine the temporal alt...
关键词：acute ischemic stroke alpha-smooth muscle cerebral blood flow MICROCIRCULATION no-reflow phenomenon PERICYTES platelet endothelial cell adhesion molecule-1 platelet-derived growth factor receptor beta vascular endothelial cells 
Therapeutic effects of the extract of Sancao Formula, a Chinese herbal compound, on imiquimod-induced psoriasis via cysteine-rich protein 61被引量：3
《Journal of Integrative Medicine》2022年第4期376-384,共9页Wan-jun Guo Yi Wang Yu Deng Lin-yan Cheng Xin Liu Ruo-fan Xi Sheng-jie Zhu Xin-yi Feng Liang Hua Kan Ze Jian-yong Zhu Dong-jie Guo Fu-lun Li 
supported by National Natural Science Foundation of China (No. 81803982, 82004366, and 82074428);Clinical Research Plan of Shanghai Shenkang Hospital Development Center(No. SHDC2020CR4041);Shanghai Municipal Commission of Science and Technology (No. 20XD1423600, 20DZ2301900);Sailing Program of Shanghai Rising-Star Program (No. 22YF1449700);the Project of Shanghai University of Traditional Chinese Medicine(No. Y2020064, Y2021019);Shanghai Municipal Commission of Economy and Information Technology,Shanghai Artificial Intelligence Innovation and Development Project-Intelligent Dermatology Clinic Based on Modern TCM Diagnostic Technology (No. 2020-RGZN-02038)。
Objective: Psoriasis is a common chronic inflammatory skin disease that is prone to recurrence, and the proinflammatory factor, cysteine-rich protein 61(Cyr61), is important in its pathophysiology. Long-term clinical ...
关键词：Traditional Chinese medicine Sancao Formula PSORIASIS Plant extracts Cysteine-rich protein 61 Intercellular cell adhesion molecule-1 
Effect of Ilizarov external fixation combined with negative pressure sealing drainage and antibiotics in the treatment of infective tibial nonunion被引量：1
《Journal of Hainan Medical University》2019年第22期37-41,共5页Guang Li You-Qiang Wei Qi-Fa Guo Hai-Yun Zhang Luosong Jiumei Zhong-Lin Lu Chang-Shuai Li 
Qinghai provincial commission of health and family planning appropriate technology promotion project(2018-wjtg-03).
Objective:Observation on the effect of Ilizarov external fixation combined with vacuum pressure sealing drainage and antibiotics in the treatment of infective tibial nonunion.Methods:79 patients with tibial infective ...
关键词：ILIZAROV external fixation technology vacuum pressure sealing drainage ANTIBIOTICS INFECTIVE tibial NONUNION bone healing time serum INTERCELLULAR adhesion MOLECULE-1 level 
AF1q inhibited T cell attachment to breast cancer cell by attenuating Intracellular Adhesion Molecule-1 expression被引量：1
《Journal of Cancer Metastasis and Treatment》2019年第3期20-31,共12页Jino Park Jae Yeon Hwang Alexandra Thore Soojin Kim Tomiteru Togano Shotaro Hagiwara Juw Won Park William Tse 
The work was supported by the start-up funds from James Graham Brown Cancer Center,University of Louisville,and an award from the Kentucky Lung Cancer Research Foundation to Tse W.Part of this work was performed with assistance of the UofL Genomics Facility,which is supported by NIH/NIGMS KY-INB(P20GM103436);the James Graham Brown Foundation,and user fees
Aim: To investigate whether AF1q, overexpressed in metastatic cells compared with the primary tumor cells, plays a pivotal role in breast cancer metastasis. Methods: To investigate whether AF1q has a responsibility in...
关键词：MLLT11 AF1q intercellular adhesion molecule-1 breast cancer METASTASIS RNA-sequencing 
Change of Inflammatory Factors in Patients with Acute Coronary Syndrome被引量：52
《Chinese Medical Journal》2018年第12期1444-1449,共6页Cai-Yun Ma Zhen-Ye Xu Shao-Ping Wang Hong-Yu Peng Fang Liu Jing-Hua Liu Feng-Xue Ren 
Background： Acute coronary syndrome （ACS） is closely related to unstable plaques and secondary thrombosis. The inflammatory cells in plaques and their inflammatory products may be the cause for plaque instability a...
关键词：Acute Coronary Syndrome Chitinase-3-Like Protein 1 Coronary Heart Disease Intracellular Adhesion Molecule-1：Lipoprotein-Associated Phospholipase A2 
Changes in nitric oxide,angiotensinⅡ,angiopoietin-like protein 4 mRNA,neuregulin 1 mRNA,and platelet endothelial cell adhesion molecule-1 in rats with acute blood stasis induced by high-molecular-weight dextran被引量：3
《Journal of Traditional Chinese Medicine》2017年第6期846-853,共8页Feng Yu Zhang Junxiu Li Shaodan Liu Yi Zhang Yin Guo Yunxia Yang Minghui 
Supported by the National Program on Key Basic Research Project(973 Program:Study of Choroid Theory Based On Cardiac Cerebrovascular Disease.No.2012CB518601)
OBJECTIVE: To investigate the influence of acute blood stasis on nitric oxide(NO), angiotensin Ⅱ(Ang Ⅱ), angiopoietin-like protein 4(ANGPTL4)m RNA, neuregulin 1(NRG-1) m RNA, and platelet endothelial cell adhesion m...
关键词：Blood stasis Basic theory of TraditionalChinese Medicine Endothelial cells ANGIOTENSIN Ⅱ  NEUREGULIN-1 Antigens  CD31 
Relationship between Two Blood Stasis Syndromes and Inflammatory Factors in Patients with Acute Coronary Syndrome被引量：21
《Chinese Journal of Integrative Medicine》2017年第11期845-849,共5页MA Cai-yun LIU Jing-hua LIU Jian-xun SHI Da-zhuo XU Zhen-ye WANG Shao-ping JIA Min ZHAO FU-hai JIANG YUE-rong MA Qin PENG Hong-yu LU Yuan ZHENG Ze REN Feng-xue 
Supported by National Basic Research Program of China(973 program,No.2015CB554404)
Objective： To investigate the relationship between inflammatory factors and two Chinese medicine（CM） syndrome types of qi stagnation and blood stasis（QSBS） and qi deficiency and blood stasis（QDBS） in patients w...
关键词：coronary heart disease Chinese medicine qi deficiency and blood stasis syndrome qi stagnation and blood stasis syndrome inflammation intracellular adhesion molecule-1 chitinase-3-like protein 1 lipoprotein-associated phospholipase A2 
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