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Developmental Origins of Human Cortical Oligodendrocytes and Astrocytes被引量:6
《Neuroscience Bulletin》2022年第1期47-68,共22页Lin Yang Zhenmeiyu Li Guoping Liu Xiaosu Li Zhengang Yang 
This work was supported by grants from National Key Research and Development Program of China(2018YFA0108000);National Natural Science Foundation of China(31820103006,31630032,and 32070971);Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);ZJ Lab,and Shanghai Center for Brain Science and Brain-Inspired Technology.We thank Dr.John L.Rubenstein for critical reading of the manuscript.
Human cortical radial glial cells are primary neural stem cells that give rise to cortical glutaminergic projection pyramidal neurons, glial cells (oligodendrocytes and astrocytes) and olfactory bulb GABAergic interne...
关键词:Radial glial cell Intermediate progenitor cell EGFR HOPX OLIGODENDROCYTE ASTROCYTE Olfactory bulb interneuron Cerebral cortex HUMAN 
Optimal time for subarachnoid transplantation of neural progenitor cells in the treatment of contusive spinal cord injury被引量:2
《Neural Regeneration Research》2013年第5期389-396,共8页Yan Liu Ying Zhou Chunli Zhang Feng Zhang Shuxun Hou Hongbin Zhong Hongyun Huang 
supported by the People’s Liberation Army Fund for Special Projects of Medical Sciences, No. 06G114
This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutive...
关键词:neural regeneration spinal cord injury subarachnoid space cell transplantation neural progenitor cells time window grants-supported paper photographs-containing paper NEUROREGENERATION 
Endothelial progenitor cells with Alzheimer's disease被引量:6
《Chinese Medical Journal》2011年第6期901-906,共6页KONG Xiao-dong ZHANG Yun LIU Li SUN Ning ZHANG Ming-yi ZHANG Jian-ning 
Background Endothelial dysfunction is thought to be critical events in the pathogenesis of Alzheimer's disease (AD).Endothelial progenitor cells (EPCs) have provided insight into maintaining and repairing endothe...
关键词:endothelial progenitor cells Alzheimer's disease vascular dementia 
Effects of aspirin on number,activity and inducible nitric oxide synthase of endothelial progenitor cells from peripheral blood被引量:8
《Acta Pharmacologica Sinica》2006年第4期430-436,共7页Tu-gang CHEN Jun-zhu CHEN Xu-dong XIE 
Project supported by Science and Technology Foundation of Zhejiang Province(№021107613);Health Science Studying Foundation of Zhejiang Province(№2003A043).
Aim: To investigate whether aspirin has an influence on endothelial progenitor cells (EPC). Methods: Total mononuclear cells (MNC) were isolated from peripheral blood by Ficoll density gradient centrifugation, t...
关键词:ASPIRIN endothelial progenitor cells celladhesion cell count cell movement celldivision physiologic neovascularization 
Changes in expression and secretion patterns of fibroblast growth factor 8 and Sonic Hedgehog signaling pathway molecules during murine neural stem/progenitor cell differentiation in vitro被引量:4
《Neural Regeneration Research》2012年第22期1688-1694,共7页Jiang Lu Kehuan Lu Dongsheng Li 
supported by the National Natural Science Foundation of China,No.81070614;the Key Project of the Natural Science Foundation of Hubei Province of China,No.2008CDA044;the Natural Science Foundation of Hubei University of Medicine,No.2011QDZR-2
In the present study, we investigated the dynamic expression of fibroblast growth factor 8 and Sonic Hedgehog signaling pathway related factors in the process of in vitro hippocampal neural stem/progenitor cell differ...
关键词:neural stem cells neural progenitor cells fibroblast growth factor 8 Sonic Hedgehog signalpathway SECRETION dynamic DIFFERENTIATION NEURONS neural regeneration 
Hypoxia confers protection against apoptosis via the PI3K/Akt pathway in endothelial progenitor cells被引量:3
《Acta Pharmacologica Sinica》2008年第12期1425-1431,共7页Tao DAI Hao ZHENG Guo-sheng FU 
Aim: The recruitment of endothelial progenitor cells (EPC) to ischemia has recently been suggested as an important mechanism of tissue repair. Although tissue ischemia can facilitate EPC mobilization, recruitment, ...
关键词:HYPOXIA endothelial progenitor cell phosphati-dylinositol 3-kinase/Akt APOPTOSIS 
Biological properties of neural progenitor cells isolated from the hippocampus of adult cynomolgus monkeys被引量:16
《Chinese Medical Journal》2006年第2期110-116,共7页YUE Feng CHEN Biao WU Di DONG Kai ZENG Si-en ZHANG Yu 
This work was supported by grants from the National Basic Research Program of China (No.973, 2001CB510104), National Natural Science Foundation of China (No. 30460141), and Program for New Century Excellent Talents in University (2005).
Background The existence of neurogenesis in the hippocampus of adult nonhuman primates has been confirmed in recent years, however, the biological properties of adult neural stem cells or neural progenitor cells (NPC...
关键词:stem cells progenitor cells cell differentiation HIPPOCAMPUS PRIMATES ADULT 
Upregulation of stromal cell-derived factor-1 alpha/CXCR4 axis-induced migration of human neural progenitors by tumor necrosis factor-alpha and interleukin-8
《Neural Regeneration Research》2009年第11期832-837,共6页Jing Qu Hongtao Zhang Guozhen Hui Xueguang Zhang Huanxiang Zhang 
the National Natural Science Foundation of China,No.30671041;the National Basic Research Program of China(973 Program),No. 2005CB623902
BACKGROUND: Studies of several animal models of central nervous system diseases have shown that neural progenitor cells (NPCs) can migrate to injured tissues. Stromal cell-derived factor 1 alpha (SDF-la), and its...
关键词:human neural progenitor cells MIGRATION stromal cell-derived factor 1 alpha CXCR4 tumor necrosis factor-α INTERLEUKIN-8 
Live-cell imaging:new avenues to investigate retinal regeneration被引量:1
《Neural Regeneration Research》2017年第8期1210-1219,共10页Manuela Lahne David R.Hyde 
supported by NIH-NEI grants to DRH(R01-EY018417,R01-EY024519);the Center for Zebrafish Research,University of Notre Dame,USA
Sensing and responding to our environment requires functional neurons that act in concert. Neuronal cell loss resulting from degenerative diseases cannot be replaced in humans, causing a functional impairment to integ...
关键词:multiphoton microscopy live-cell imaging ZEBRAFISH interkinetic nuclear migration tissue culture retinal regeneration Miiller glia neuronal progenitor cell differentiation PHAGOCYTOSIS 
Autophagy in hepatic progenitor cells modulates exosomal miRNAs to inhibit liver fibrosis in schistosomiasis
《Frontiers of Medicine》2024年第3期538-557,共20页Yue Yuan Jiaxuan Li Xun Lu Min Chen Huifang Liang Xiao-ping Chen Xin Long Bixiang Zhang Song Gong Xiaowei Huang Jianping Zhao Qian Chen 
supported by the National Natural Science Foundation of China(No.82003403(Jianping Zhao),No.81974077,and No.82170633(Qian Chen)).
Schistosoma infection is one of the major causes of liver fibrosis.Emerging roles of hepatic progenitor cells(HPCs)in the pathogenesis of liver fibrosis have been identified.Nevertheless,the precise mechanism underlyi...
关键词:SCHISTOSOMIASIS hepatic progenitor cell AUTOPHAGY extracellular vesicle fibrosis miRNA 
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