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Paeonol attenuated vascular fibrosis through regulating Treg/Th17 balance in gut microbiota-dependent manner被引量:7
《中国药理学与毒理学杂志》2021年第10期736-737,共2页SHI Xiao-yan HUANG Han-wen ZHOU Min LIU Ya-rong WU Hong-fei DAI Min 
National Natural Science Foundation of China(81773937)。
OBJECTIVE Atherosclerosis(AS)is a chronic inflammatory disease characterized by the accumulation of lipids,vascular fibrosis,and inflammation.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chi...
关键词:PAEONOL ATHEROSCLEROSIS gut microbiota Treg/Th17 balance vascular fibrosis 
Extrahepatic organs in the development of non-alcoholic fatty liver disease in liver transplant patients被引量:1
《Hepatobiliary Surgery and Nutrition》2022年第3期400-411,共12页Renyi Su Xuyong Wei Qiang Wei Di Lu Zuyuan Lin Shuo Wang Chuxiao Shao Xiao Xu 
National Natural Science Funds for Distinguished Young Scholar of China/International(grant No.81625003);National Science and Technology Major Project of China(grant No.2017ZX10203205);Science Funds for Young Scholar of China(grant No.81702858);Youth Program of Natural Science Foundation of Zhejiang Province(grant No.LQ17H160006).
Background and Objective:Non-alcoholic fatty liver disease(NAFLD)is highly prevalent in patients who undergo liver transplantation(LT).Whereas there is huge data on NAFLD,little is known about NAFLD in LT.In this revi...
关键词:Non-alcoholic fatty liver disease(NAFLD) liver transplant SARCOPENIA LIPID GUT 
Composition and immuno-stimulatory properties of extracellular DNA from mouse gut flora被引量:4
《World Journal of Gastroenterology》2017年第44期7830-7839,共10页Ce Qi Ya Li Ren-Qiang Yu Sheng-Li Zhou Xing-Guo Wang Guo-Wei Le Qing-Zhe Jin Hang Xiao Jin Sun 
Supported by China Postdoctoral Science Foundation,No.172774;Fund of Key Laboratory of Carbohydrate Chemistry and Biotechnology,Ministry of Education,Jiangnan University,No.KLCCB-KF201603;National Natural Science Foundation of China,No.31201805
AIM To demonstrate that specific bacteria might release bacterial extracellular DNA(e DNA) to exert immunomodulatory functions in the mouse small intestine.METHODS Extracellular DNA was extracted using phosphate buffe...
关键词:Bacterial extracellular DNA FLORA Immunestimulatory property Gut microbiota MOUSE Small intestine 
Efficacy and Safety of Washed Microbiota Transplantation to Treat Patients with Mild-to-Severe COVID-19 and Suspected of Having Gut Microbiota Dysbiosis: Study Protocol for a Randomized Controlled Trial被引量:3
《Current Medical Science》2021年第6期1087-1095,共9页Li-hao WU Zhi-ning YE Ping PENG Wen-rui XIE Jia-ting XU Xue-yuan ZHANG Harry Hua-xiang XIA Xing-xiang HE 
supported by the Special Research Project on Prevention and Control of COVID-19 in Universities of the Guangdong Provincial Education Department(No.2020KZDZX1132).
Objective:Coronavirus disease 2019(COVTD-19)is often accompanied by gastrointestinal symptoms,which are related to gut microbiota dysbiosis(GMD).Whether washed microbiota transplantation(WMT)is an effective treatment ...
关键词:COVID-19 SARS-Cov-2 virus gut microbiota MICROBIOME DYSBIOSIS washed microbiota transplantation 
Cereal type and combined xylanase/glucanase supplementation influence the cecal microbiota composition in broilers
《Journal of Animal Science and Biotechnology》2022年第5期1531-1542,共12页Dimitrios Kouzounis Jannigje G.Kers Natalia Soares Hauke Smidt Mirjam A.Kabel Henk A.Schols 
funded by Huvepharma NV。
Dietary fiber-degrading enzyme supplementation in broilers aims at off-setting the anti-nutritive effect of non-starch polysaccharides and at promoting broiler health.Recently,we demonstrated that xylanase/glucanase a...
关键词:Arabinoxylo-oligosaccharides Broiler gut microbiota Cereal non-starch polysaccharides Feed enzymes Fiber fermentation PREBIOTICS 16S rRNA 
Gut microbiota-induced CXCL1 elevation triggers early neuroinflammation in the substantia nigra of Parkinsonian mice被引量:3
《Acta Pharmacologica Sinica》2024年第1期52-65,共14页Xi-zhen Ma Lei-lei Chen Le Qu Hui Li Jun Wang Ning Song Jun-xia Xie 
supported by grants from the National Natural Science Foundation of China(32170984,31871049);the Excellent Innovative Team of Shandong Province and the Taishan Scholars Construction Project,and the Natural Science Foundation of Shandong Province(ZR2023QH110,ZR2020YQ23,and ZR2021MC116).
Gut microbiota disturbance and systemic inflammation have been implicated in the degeneration of dopaminergic neurons in Parkinson's disease(PD).How the alteration of gut microbiota results in neuropathological events...
关键词:Parkinson's disease INFLAMMATION gut microbiota CXCL1 PPAR linoleic acid 
Causality Between Gut Microbiota and Inflammatory Bowel Disease:A Bidirectional Mendelian Randomization Study
《Infectious Microbes & Diseases》2024年第2期93-99,共7页Qi Zheng Yuetong Li Jiali Ni Yong Huang Jiajun Wu Xiang Xu Guoping Sheng Lanjuan Li 
the Fundamental Research Funds for the Central Universities(2022ZFJH003);Shandong Provincial Laboratory Project(SYS202202);the Research Project of Jinan Microecological Biomedicine Shandong Laboratory(JNL-2022001A).
The exact relationship between inflammatory bowel disease(IBD)and gut microbiota(GM)is still unclear.This study aimed to explore the cause-and-effect relationship between IBD and GM by Mendelian randomization analysis...
关键词:gut microbiota inflammatory bowel disease Mendelian randomization 
意大利蜜蜂工蜂幼虫肠道发育过程中lncRNA的表达谱和调控作用
《昆虫学报》2024年第8期1050-1062,共13页赵浩东 臧贺 叶道有 陈颖 王宁 吴鹰 蒋海宾 冯睿蓉 陈大福 熊翠玲 郭睿 
国家自然科学基金面上项目(32372943,32172792);国家现代农业产业技术体系专项资金(CARS-44-KXJ7);福建省自然科学基金面上项目(2022J01131334);福建省教育厅中青年教师教育科研项目(JAT231226);福建农林大学硕士生导师团队项目(郭睿);福建农林大学科技创新专项基金(KFb22060XA);福建省大学生创新创业训练计划项目(X202310389084,X202310389086)。
【目的】解析意大利蜜蜂Apis mellifera ligustica工蜂幼虫肠道发育过程中的长链非编码RNA(long non-coding RNA,lncRNA)差异表达谱,并揭示差异表达lncRNA(differentially expressed lncRNA,DElncRNA)在幼虫肠道发育中的调控作用。【方...
关键词:意大利蜜蜂 工蜂 幼虫 长链非编码RNA 肠道 发育 
Enhanced protective effect of selenium-biofortified peptide RYNA(Se)MNDYT compared with its native peptide RYNAMNDYT in lipopolysaccharide-injured murine gut microbiota
《Food Science and Human Wellness》2024年第6期3391-3402,共12页Shujian Wu Zhenjun Zhu Mengfei Chen Aohuan Huang Yizhen Xie Jiaming Chen Liang Xue Moutong Chen Jumei Zhang Juan Wang Qingping Wu Yu Ding 
Guangzhou Basic and Applied Basic Research Project(202201010197);State Key Laboratory of Applied Microbiology Southern China(SKLAM011-2021);National Natural Science Foundation of China(32202014),Guangdong Provincial Key Laboratory(2020B121201009);Guangdong Province Academy of Sciences Special Project for Capacity Building of Innovation Driven Development(2020GDASYL-20200401002).
Selenopeptides may be a valuable bioactive compound to promote gut microbiota-targeted therapeutic methods for intestinal disease and hepatopathy.However,limited information is available on the utilization of selenope...
关键词:Selenopeptide Gut microbiota Metabolites Selenium biofortification Proteomics 
Reciprocal interactions between gut microbiota and autophagy被引量:8
《World Journal of Gastroenterology》2021年第48期8283-8301,共19页Pierre Lapaquette Jean-Baptiste Bizeau Niyazi Acar Marie-Agnès Bringer 
Agence Nationale de la Recherche,No.ANR-11-LABX-0021-01;French“Investissements d’Avenir”program,project ISITE-BFC,No.ANR-15-IDEX-0003;Conseil Régional de Bourgogne,Franche-Comté,No.RECH-E1INV-000131-0-EarlEAT;Institut Carnot Qualiment,INPROBIAUS grant;FEDER(European Funding for Regional Economic Development),EARLEAT,PO FEDER-FSE Bourgogne 2014-2020 BG 0027905 BG 0027810.
A symbiotic relationship has set up between the gut microbiota and its host in the course of evolution,forming an interkingdom consortium.The gut offers a favorable ecological niche for microbial communities,with the ...
关键词:Gut microbiota AUTOPHAGY Probiotic BRAIN LIVER MUSCLE 
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