国家自然科学基金(21175005)

作品数:6被引量:12H指数:2
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相关作者:刘虎威廖一平庞楠楠杨玉飞白玉更多>>
相关机构:北京大学北京科技大学北京师范大学更多>>
相关期刊:《Journal of Chinese Pharmaceutical Sciences》《分析科学学报》《Journal of Analysis and Testing》《化学通报(中英文)》更多>>
相关主题:质谱液相色谱铂类抗癌药物毛细管电泳相互作用更多>>
相关领域:医药卫生理学更多>>
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Supercritical Fluid Chromatography and Its Application in Lipid Isomer Separation被引量:2
《Journal of Analysis and Testing》2017年第4期330-334,共5页Shiyao Song Huwei Liu Yu Bai 
the National Natural Science Foundation of China(Nos.21527809 and 21175005).
Supercritical fluid chromatography(SFC),which uses supercritical fluid with higher diffusivity and lower viscosity than liquid as its mobile phase,can provide fast,green,high-throughput and good performance methods fo...
关键词:Supercritical fluid chromatography LIPID ISOMERS Mass spectrometry 
Plasma Lipidomic Analysis to Identify Novel Biomarkers for Hepatocellular Carcinoma
《Journal of Analysis and Testing》2017年第3期223-232,共10页Li Yang Yu Bai Xiaohong Han Yuankai Shi Huwei Liu 
the National Natural Science Foundation of China(Grant numbers,21527809 and 21175005).
Hepatocellular carcinoma(HCC)accounts for the major primary liver cancer,and its morbidity and mortality rates are very high.Identification of novel biomarkers for the early diagnosis and treatment of this disease is ...
关键词:BIOMARKER Hepatocellular carcinoma LIPIDOMICS NP/RP 2D LC-QToF/MS 
Sphingolipids Profiling of Plasma in Patients with Diabetes Mellitus Associated with Atherosclerosis by a Novel Normal-Phase UPLC-QToF MS Method
《Journal of Analysis and Testing》2017年第3期245-254,共10页Min Li Li Yang Yining Huang Yu Bai Huwei Liu 
the National Key R&D Program of China(2017YFC0906800);National Natural Science Foundation of China(Grant nos.21527809 and 21175005).
A novel normal-phase UPLC-QToF MS method was developed for sphingolipids analysis,which was then applied to separate and identify seven classes of sphingolipids in plasma.The time-consuming of this novel method was mu...
关键词:UPLC-QToF MS Diabetes mellitus ATHEROSCLEROSIS SPHINGOLIPIDS Lipidomics Cardiovascular disease 
油酸氧化产物的电喷雾离子化-离子阱-质谱裂解机理研究被引量:2
《分析科学学报》2014年第5期600-606,共7页庞楠楠 聂洪港 周宇 廖一平 刘虎威 
国家自然科学基金(No.21175005)
9,10-环氧十八酸(9,10-Epoxyoctadecanoic Acid,9,10-EODE)和9,10-邻二羟基十八酸(9,10-Dihydroxyoctadecanoic Acid,9,10-(OH)2-18∶0)是油酸的两种氧化产物。基于碰撞诱导解离,利用离子阱多级质谱对9,10-(OH)2-18∶0和9,10-EODE进行...
关键词:远离电荷中心均裂 9 10-环氧十八酸 9 10-邻二羟基十八酸 碎裂 质谱 
Comparative study on different derivatization procedures for analysis of recombinant human erythropoietin by capillary electrophoresis with laser-induced fluorescence detection
《Journal of Chinese Pharmaceutical Sciences》2014年第5期317-323,共7页杨霞 庞楠楠 付晓芳 尹红锋 廖一平 刘虎威 
National Natural Science Foundation of China(Grant No.20635001 and 21175005)
Human erythropoietin (hEPO), an endogenous glycoprotein, plays a fundamental role in erythropoiesis controlling the formation of red blood cells. Production of recombinant human erythropoietin (rhEPO) has made it ...
关键词:Recombinant human erythropoietin Capillary electrophoresis Laser-induced fluorescence detection On-capillaryderivatization 
铂类抗癌药物及其作用机理的分析技术进展被引量:8
《化学通报》2013年第10期867-877,共11页刘一 杨玉飞 白玉 刘虎威 
科技部仪器专项基金项目(2012YQ090194-9);国家自然科学基金项目(21175005)资助
以顺铂为代表的铂类抗癌药物已投入临床应用将近30年,因强大的抗癌活性及广谱的抗癌效果而得到了迅速发展和广泛应用,卡铂则是另一个成功应用的铂类抗癌药。这些抗癌药的抗癌机理被普遍认为是Pt(Ⅱ)与DNA的亲电作用,进而形成DNA链交联...
关键词:铂族抗癌药物 液相色谱 毛细管电泳 质谱 相互作用 
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