《Chinese Medical Journal》

作品数：16510被引量：75077H指数：55
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《Chinese Medical Journal》
主办单位：中华医学会
最新期次：2025年3期更多>>
发文主题：PATIENTSTREATMENTAFTERDIAGNOSISCHINESE更多>>
发文领域：医药卫生生物学农业科学化学工程更多>>
发文作者：黎磊石刘志红曹克将杨伟炎蒋次鹏更多>>
发文机构：复旦大学中国人民解放军总医院上海交通大学医学院附属瑞金医院北京大学更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金广东省自然科学基金更多>>
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Role of silent mutations in KRAS-mutant tumors
《Chinese Medical Journal》2025年第3期278-288,共11页Jun Lu Chao Zhou Feng Pan Hongyu Liu Haohua Jiang Hua Zhong Baohui Han 
National Natural Science Foundation of China(Nos.82473102,82272913,82301980,and 82072573);National Multi-disciplinary Treatment Project for Major Disease(No.2020NMDTP);Chinese Society of Clinical Oncology(Nos.Y-2019AZZD-0355 and Y-QL2019-012);Shanghai Jiao Tong University(No.YG2021QN12)
Silent mutations within the RAS gene have garnered increasing attention for their potential roles in tumorigenesis and therapeutic strategies.Kirsten-RAS(KRAS)mutations,predominantly oncogenic,are pivotal drivers in v...
关键词：MUTATIONS Silent mutation TUMOR Biological characteristics 
Cancer therapy-related interstitial lung disease
《Chinese Medical Journal》2025年第3期264-277,共14页Chengzhi Zhou Haiyi Deng Yilin Yang Fei Wang Xinqing Lin Ming Liu Xiaohong Xie Tao Luan Nanshan Zhong 
Guangzhou Science and Technology Major Clinical Project(No.2023C-DZ06);China Primary Health Care Foundation(No.BH001496)
With the increasing utilization of cancer therapy, the incidence of lung injury associated with these treatments continues to rise. The recognition of pulmonary toxicity related to cancer therapy has become increasing...
关键词：Cancer therapy Interstitial lung disease Lung toxicity 
Chinese guidelines on remote programming of deep brain stimulation for patients with Parkinson’s disease
《Chinese Medical Journal》2025年第3期261-263,共3页Fangang Meng Jie Zhang Wenbin Zhang Ling Chen Jianjun Wu Shanshan Mei Lijuan Wang Jianguo Zhang The Chinese Medical Association Neurosurgery Branch of Functional Neurosurgery Group The Chinese Medical Association Neurology Branch of Parkinson’s Disease,Movement Disorders Group The Chinese Physician Association Neurosurgeon Branch of Functional Neurosurgery Expert Committee The Chinese Physician Association Neurologist Branch of Parkinson’s Disease and Movement Disorders Professional Committee China Neuromodulation Union Society Whole-process Management of Neuromodulation and Chinese Expert Committee on Deep Brain Stimulation for Parkinson’s Disease 
National Key Research and Development Program of China(Nos.2022YFC2405100 and 2021YFC2401200);National Natural Science Foundation of China(No.81830033);Key R&D Program of Jiangsu Science and Technology Project(No.BE2022049);Key Research and Development Program of Henan Province(No.241111310100)
Deep brain stimulation(DBS)is a neurosurgical procedure that allows targeted circuit-based neuromodulation;it is also a standard of care for Parkinson’s disease(PD).[1]Postoperative DBS programming is a crucial step ...
关键词：stimulation parameters neurosurgical procedure deep brain stimulation dbs release symptoms parkinson s disease which remote programming postoperative programming deep brain stimulation 
Circulating immunological transcriptomic profile identifies DDX3Y and USP9Y on the Y chromosome as promising biomarkers for predicting response to programmed death 1/programmed death ligand 1 blockade
《Chinese Medical Journal》2025年第3期364-366,共3页Liting You Zhaodan Xin Feifei Na Min Chen Yang Wen Jin Li Jiajia Song Ling Bai Jianzhao Zhai Xiaohan Zhou Binwu Ying Juan Zhou 
National Natural Science Foundation of China(No.NSFC82372331);Project of Science and Technology Department of Sichuan Province(Nos.2024NSFSC1551 and 2023NSFSC0716)
To the Editor:Immune checkpoint inhibitors(ICIs)have shown remarkable clinical responses;however,their efficacy remains limited to a small subset of patients.Peripheral blood mononuclear cells(PBMCs)offer an effective...
关键词：circulating immunological transcriptomic profile blood mononuclear cells pbmcs offer programmed death assess tumor immune status programmed death ligand immune checkpoint inhibitors biomedical ethics committee ddx y 
DDX24 promotes lymphangiogenesis and lymph node metastasis via AGRN production in cervical squamous cell carcinoma
《Chinese Medical Journal》2025年第3期361-363,共3页Baibin Wang Yuan Zhuang Chongrong Weng Yanhui Jiang Bingfan Xie Lijie Wang Yingying Dong Xiangpei Fang Jianzhong He Xiaojin Wang Huanhuan He Yong Chen Huilong Nie 
National Natural Science Foundation of China(Nos.92159105 and 81872113);Guangdong Province(No.2020A0505100028)
To the Editor:Cervical cancer(CC)is the second leading cause of cancer death in women,representing a major global health challenge.[1]Cervical squamous cell carcinoma(CSCC)accounts for 70%of CC cases,and pelvic lymph ...
关键词：pelvic lymph node metastasis squamous cell carcinoma cscc accounts ddx cervical squamous cell carcinoma agrn LYMPHANGIOGENESIS underlying mechanisms lymph node metastasis 
Locoregional treatments of metastatic internal mammary node following neoadjuvant chemotherapy
《Chinese Medical Journal》2025年第3期358-360,共3页Jinhui Zhang Huajie Guan Cailu Song Lingrui Liu Hailin Tang Jin Wang 
National Natural Science Foundation of China(No.82273399);Natural Science Foundation of Guangdong Province(No.2022A1515012229);National Natural Science Foundation of China(No.82372742)
To the Editor:Neoadjuvant chemotherapy(NAC)significantly improves the prognosis for patients with breast cancer with internal mammary lymph node(IMN)involvement,[1]but the locoregional treatment of IMNs including IMN ...
关键词：surgical approaches locoregional treatment breast cancer imn boost irradiation imnb cardiopulmonary side effects metastatic internal mammary node internal mammary lymph node imn involvement surgical dissection 
O-linked β-N-acetylglucosaminylation in lung cancer and beyond: A multidimensional perspective
《Chinese Medical Journal》2025年第3期355-357,共3页Jinxiu Jiang Xiaochun Huang Jianguo Feng Li Liu Yulin Liu Jing Jia 
National Natural Science Foundation of China(No.82000052);Sichuan Science and Technology Program(2022YFS0632);joint foundation of Luzhou Government and Southwest Medical University(Nos.2020LZXNYDJ11,2021LZXNYD-J25);
To the Editor:O-linkedβ-N-acetylglucosaminylation(OGlcNAcylation)is a crucial post-translational modification regulated by two enzymes,O-GlcNAc transferase(OGT)and O-GlcNAcase(OGA).Dysregulation of O-GlcNAcylation ha...
关键词：lung cancer TUMORIGENESIS OGT post translational modification o linked n acetylglucosaminylation OGA cancer cell adap disease processes 
Research trends and hotspots of intratumor microbiome:A comprehensive visualization and bibliometric study from 2012 to 2024
《Chinese Medical Journal》2025年第3期376-378,共3页Chaoyue Xiao Xiang Feng Tiantian Zhao Gouping Ding Yawen Gao 
This work was supported by the National Natural Science Foundation of China(No.82150006);Chinese Society of Clinical Oncology Research Foundation(Nos.Y-HR2017-117,Y-HH202102-0060);Beijing Medical and Health Foundation(No.YWJKJJHKYJJ-F3046D);Qujiang District Quzhou City Life Oasis Public Service Center(No.BJHA-CRP-040);Wu Jieping Medical Foundation(No.320.6750.2023-05-10)to Yawen Gao.
To the Editor:As early as in the mid-19th century,microbiologists first recognized multiple microorganisms within human tumors.Nevertheless,the perceptions of intratumor microbiome have made little progression during ...
关键词：low biomass microbiome detection techniques analytical tools bibliometric study intratumor microbiome host microbe interplays 
Leonurus japonicus:A promising anticancer Chinese medicine modulating regulated cell death
《Chinese Medical Journal》2025年第3期373-375,共3页Xue Li Mingyu Han Huali Fan Sui Li Fu Peng 
To the Editor:According to the latest statistics published by National Cancer Center of China,approximately 4,824,700 cancer cases were newly diagnosed and 2,574,200 patients died from cancer in China in 2022.[1]Uncon...
关键词：Leonurus japonicus physiological death resistancewhich drug discovery pharmacological activities reprogram cancerous suicide cell proliferation cancer cell death 
Prevalence and influencing factors of mild cognitive impairment and dementia in Chinese older adults:A community-based study
《Chinese Medical Journal》2025年第3期370-372,共3页Wei Li Lin Sun Ling Yue Shifu Xiao 
China Ministry of Science and Technology(No.STI2030-Major Projects-2022ZD0213100);National Natural Science Foundation of China(Nos.82101564,82001123,and 82271607);Feixiang Program of Shanghai Mental Health Center(No.2020-FX-03);Shanghai Clinical Research Center for Mental Health(No.19MC1911100);Shanghai brain health foundation(No.SHBHF2016001);Chinese Academy of Sciences(No.XDA12040101);Shanghai Clinical Research Center for Mental Health(Nos.SCRC-MH,19MC1911100);Shanghai Science and Technology Committee(No.20Y11906800)
To the Editor:Dementia is a common degenerative disease characterized by a progressive decline in cognitive function and the ability to perform activities of daily living.In 2010,>35 million people worldwide were livi...
关键词：mild cognitive impairment PREVALENCE influencing factors Chinese older adults DEMENTIA community based study epidemiological studies cognitive impairment mci 
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