《Open Journal of Apoptosis》

作品数:31被引量:17H指数:2
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《Open Journal of Apoptosis》
主办单位:美国科研出版社
最新期次:2019年1期更多>>
发文主题:APOPTOSISCELL_DEATHANTISENSEOLIGONUCLEOTIDESBCL-2更多>>
发文领域:医药卫生更多>>
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Cell Death Effects of the Phthalate 2-Ethyl-1-Hexanol on Human Linfoblast Cells
《Open Journal of Apoptosis》2019年第1期1-15,共15页Karoline Rios Christian Vélez Beatriz Zayas 
Phthalates have been used in a wide variety of consumer goods. Their versatility as plasticizers has translated into worldwide use in a vast array of consumer products. These compounds can leach into matrices, such as...
关键词:PHTHALATES 2-Ethyl-1-Hexanol Diethylhexyl PHTHALATE Autophagy Apoptosis LYMPHOBLAST Caspase 
Sodium Fluoride Induces Hepato-Renal Oxidative Stress and Pathophysiological Changes in Experimental Animals
《Open Journal of Apoptosis》2018年第1期1-23,共23页Azab Elsayed Azab Mohamed Omer Albasha J. M. Jbireal Almokhtar A. Adwas 
The liver is a primary site for xenobiotics detoxification, and its metabolism is readily altered by toxicity. The kidney is a common target for toxic xenobiotics due to its capacity to extract and concentrate toxic s...
关键词:Sodium FLUORIDE TOXICITY OXIDATIVE Stress Hepatorenal HISTOPATHOLOGICAL CHANGES Hepatorenal Pathophysiological CHANGES 
Antiepileptic Drug-Induced Apoptosis Was Prevented by L-Type Calcium Channel Activator in Cultured Rat Cortical Cells
《Open Journal of Apoptosis》2017年第2期17-27,共11页Tsuneo Takadera Masashi Aoki Naruto Nakanishi 
Experimental data have shown that antiepileptic drugs cause neurodegeneration in developing rats. Valproate (VPA) is the drug of choice in primary generalized epilepsies, and carbamazepine (CBZ) is one of the most pre...
关键词:ANTIEPILEPTIC Drug Valproate CARBAMAZEPINE L-TYPE Calcium Channel GLYCOGEN SYNTHASE Kinase-3 Apoptosis 
Evaluation of Stress Response and Apoptosis on Leucocytes in TIVA versus Balanced Anesthesia
《Open Journal of Apoptosis》2017年第1期1-16,共16页G. Soto F. Pignolo F. Calero F. Saucina L. Lainatti S. Molinari G. Harvey 
Background: The aim of this study was to assess the stress response and apoptosis on leucocytes, in patients under two different anesthetics techniques. Methods: Thirty patients ASA I-II were prospectively randomized ...
关键词:Propofol-Sevoflurane-Hemodynamics Response-Cortisol-Apoptosis in Leucocytes-Annexin V-Propidium Iodide 
Effect of a Nutrient Mixture on Fanconi Anemia Fibroblast and Normal Human Dermal Fibroblast: A Comparison
《Open Journal of Apoptosis》2016年第1期1-8,共8页Mohd Waheed Roomi Tatiana Kalinovsky Aleksandra Niedzwiecki Matthias Rath 
Fanconi anemia (FA) is a fatal heterogeneous autosomal recessive disorder, characterized by progressive bone marrow failure, congenital defect and cancer predisposition. Cell culture from FA fibroblast (FAF) displays ...
关键词:Fanconi Anemia Fibroblasts Normal Human Dermal Fibroblasts NUTRIENTS Cell Viability MMP-2 and 9 Apoptosis 
Varicose Veins, Retinal Tears and Deep Vein Thrombosis, New Insights into the Causes from Adams Disease
《Open Journal of Apoptosis》2015年第3期59-61,共3页James David Adams Jr. 
Adams disease is the consequence of overly active transient receptor potential cation channels (TRP). This case report presents a patient suffering from multiple vascular problems and may provide new insights into the...
关键词:Transient Receptor Potential Cation Channels Deep VEIN THROMBOSIS VARICOSE VEINS RETINAL TEARS Adams Disease 
Altered Oncogene Activity Contributes to Compensation for Antisense Suppression of Bcl-2 and Tumor Resistance被引量:1
《Open Journal of Apoptosis》2015年第3期62-70,共9页Marvin Rubenstein Courtney M. P. Hollowell Patrick Guinan 
Antisense oligonucleotides (oligos) have targeted growth regulatory proteins in prostate cancer models. To identify compensatory alterations in the expression of non-targeted genes we evaluate mono- and bispecific oli...
关键词:ANTISENSE OLIGONUCLEOTIDES Prostate Cancer BCL-2 Gene COMPENSATION Therapy 
Apoptosis and Skeletal Muscle in Aging被引量:1
《Open Journal of Apoptosis》2015年第2期41-46,共6页Giuseppe Musumeci Rosa Imbesi Marta Anna Szychlinska Paola Castrogiovanni 
Apoptosis is highly considered as a possible mechanism in the aging process of skeletal muscle. Age-related apoptosis pathways in aging skeletal muscle are several, and apoptotic stimuli considered as initiators could...
关键词:APOPTOSIS AGING SKELETAL MUSCLE Exercise NUTRITION 
BAX G(-248)A Gene Polymorphism and Its Association with Risk of Non-Small Cell Lung Cancer—A Case Control Study
《Open Journal of Apoptosis》2015年第2期47-58,共12页Jamsheed Javid Rashid Mir Pramod Kumar Julka Prakash Chandra Ray Alpana Saxena 
Pro-apoptotic Bcl-2 protein BAX is an important member of mitochondrial dependent apoptosis regulation and ultimately plays a pivotal role in malignancies. A promoter G(-248)A polymorphism in the TP53 binding region o...
关键词:BAX G(-248)A POLYMORPHISM PIRA-PCR NSCLC RISK 
Following Inhibition of BCL-2 by Antisense Oligonucleotides Compensatory Suppression of Apoptosis Involves the Direct Signal Transduction Pathway of LNCaP Cells被引量:1
《Open Journal of Apoptosis》2015年第1期1-10,共10页Marvin Rubenstein Courtney M. P. Hollowell Patrick Guinan 
Previously we have shown that when LNCaP cells are treated with antisense oligonucleotides (oligos) directed against BCL-2, compensatory changes in non-targeted genes take place in attempts to restore apoptosis and pr...
关键词:ANTISENSE OLIGONUCLEOTIDES Prostate Cancer Fas FAS-LIGAND PD-1 PD-1 Ligand Caspase-3 BCL-2 Bax Therapy 
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