《Journal of Pharmaceutical and Biopharmaceutical Research》

作品数：9被引量：3H指数：1
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《Journal of Pharmaceutical and Biopharmaceutical Research》
主办单位：新加坡SyncSci出版有限责任公司
最新期次：2019年2期更多>>
发文主题：DOCKINGCONFORMATIONMOLECULARLIPASESPECTROSCOPY更多>>
发文领域：医药卫生更多>>
发文基金：国家自然科学基金更多>>
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Microbial synthesis of anti-tumor agent oxysophoridine through one step by filamentous fungus
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第2期48-52,共5页Qingfeng Meng Xuan Zhou Xu Ran Song Yan Shaobin Fu 
Sophoridine and oxysophoridine are alkaloids extracted from Chinese traditional medicinewith significant antitumor activities. Computer-aided design and preliminary structure-activity relationship studiesshowed that t...
关键词：BIOTRANSFORMATION ALKALOID FUNGUS natural product condition optimization 
Spectroscopic and molecular docking studies on the binding mechanism of Mobic and lipase被引量：2
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第2期53-60,共8页Baosheng Liu Xu Cheng Hongcai Zhang 
Under simulated physiological conditions (pH=7.40), the interaction between non-steroidal anti-inflammatory drug Mobic and lipase was studied by fluorescence spectra, ultraviolet absorption spectra, circular dichroism...
关键词：SPECTROSCOPY Mobic LIPASE CONFORMATION MOLECULAR DOCKING interaction 
Synthesis of cocrystals of sulfonyl urea class drug using suitable coformers for enhancement of aqueous solubility
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第2期61-69,共9页Santosh S. Chhajed Yatish R. Rajderkar Anjali B. Tajanpure Jayprakash B. Ugale Sanjay J. Kshirsagar 
The pharmaceutical cocrystals and its engineering is widely accepted phenomenon regarding to the enhancement of aqueous solubility of poorly soluble drugs. The pharmaceutical cocrystals have the great ability to impro...
关键词：COCRYSTALS COCRYSTAL engineering BIOPHARMACEUTICAL classification system green CHEMISTRY 
Pharmacy, the interdisciplinary field of science
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期I0001-I0002,共2页Professor Pal Perjesi 
Pharmacy is an interdisciplinary field of science, which covers the knowledge of fate of drugs (pharmacons), excipients and formulated pharmaceutical products outside and inside the body. Separation of pharmacy as a s...
关键词：PHARMACY formulated PHARMACEUTICAL PRODUCTS OUTSIDE MEDICINE 
Functionalization of carbopol with NVP for designing antibiotic drug loaded hydrogel dressings for better wound management
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期1-14,共14页Baljit Singh Abhishek Dhiman 
In the present work an attempt has been made to design the antibiotic drug loaded carbopolpoly( NVP) based hydrogel wound dressings for better wound care. The polymer films were characterized by SEM-EDX, AFM, FTIR, 13...
关键词：drug delivery 1-Vinyl-2-pyrollidone hydrogel WOUND DRESSING 
The preparation of Garcinia Glycosides solid dispersion and intestinal absorption by rat in situ single pass intestinal perfusion
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期15-20,共6页Shengnan Li Jingchao Ji Yinghui Chen Ye Chen Ju Liu Yang Wang Hongsheng Liu 
Garcinia Glycosides is a candidate drug obtained by structural modification of Gambogic Acid (GA), which was acquired through High Throughput Screening(HTS). As Garcinia Glycosides is an effective but insoluble anti-t...
关键词：GARCINIA GLYCOSIDES solid dispersion INTESTINAL PERFUSION in SITU single-pass PERFUSION method 
Binding studies of trans-resveratrol with superoxide dismutase (SOD1): Docking assessment and Thermoanalysis
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期21-27,共7页Janhvi Dureja Renu Chadha Maninder Karan Akshita Jindal Kunal Chadha 
The binding pursuits of trans-resveratrol(t-RSV),an amazing health supplement are investigated with an antioxidant enzyme,superoxide dismutase(SOD1).The aim of the study is to dock t-RSV on the adrenaline binding site...
关键词：TRANS-RESVERATROL superoxide DISMUTASE DOCKING MICROCALORIMETRY binding constant free energy 
Spectroscopic study on the mechanism of meloxicam and α-amylase
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期28-35,共8页Xu Cheng Baosheng Liu Hongcai Zhang 
In order to explore the mechanism of action of meloxicam and α-amylase. The interaction between the rheumatoid arthritis drug meloxicam and α-amylase was studied by fluorescence spectroscopy, synchronous fluorescenc...
关键词：DRUG protein fluorescence analysis CONFORMATION molecular DOCKING BINDING rate 
SeDeM Expert System: A review and new perspectives被引量：1
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期36-47,共12页Mingxian Gu Tianbing Guan Shulin Wan Han Zhang Xuelian Li Songtao Kong Jianbing Ren Huimin Sun Chuanyun Dai 
The SeDeM Expert System was first known as a galenic pre-formulation system, which was based on the experimental research and quantitative determination of powdered substances. And the mathematical formula provided by...
关键词：SeDeM EXPERT System radar GRAPH POWDER direct compression pre-formulation coprocessed 
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