Financial support from the Science and Technology Plan Project of Wuhan(2023020402010631);the Natural Science Foundation of Beijing(7222262);Opening Project of Key Laboratory of Biomedical Polymers of Ministry of Education at Wuhan University(20230401)was gratefully acknowledged.
Gold nanoparticles have recently been exploited as versatile nanocarriers in diagnostic and therapeutic drug delivery for cancer nanomedicine, owing to their biocompatibility, low biotoxicity, surface modifiability an...
supported by the National Natural Science Foundation of China[52073216 and 51773130].
Immune checkpoint blockade therapy provides a new strategy for tumor treatment;however,the insufficient infiltration of cytotoxic T cells and immunosuppression in tumor microenvironment lead to unsatisfied effects.Her...
Funded by National Natural Science Foundation of China(82172076);Key Scientific Program of Jiangsu Provincial Health Commission(ZD2021033);Gusu Health Leading Talent Program of Suzhou(GSWS2021020);Discipline construction project of the Second Affiliated Hospital of Soochow University(XKTJXK202004);Scientific Program of Suzhou Municipal Health and Health Committee(LCZX202004);Project of Medical New Technology Assistance of the Second Affiliated Hospital of Soochow University(23ZL004 and 23ZL012).
Cartilage tissue engineering offers hope for tracheal cartilage defect repair.Establishing an anti-inflammatory microenvironment stands as a prerequisite for successful tracheal cartilage restoration,especially in imm...
supported by the National Natural Science Foundation of China(T2288101,31971266,82272152);Guangdong Basic and Applied Basic Research Foundation(2022A1515011925);National Key R&D Program of China(2021YFC2400700);Science and Technology Innovation Program of Guangdong Province Medical Products Administration(2022ZDZ11);Applied Basic Research Program of Guangzhou city of China(202201010040).
Mitochondrial network architecture,which is closely related to mitochondrial function,is mechanically sensitive and regulated by multiple stimuli.However,the effects of microtopographic cues on mitochondria remain poo...
support from the Key Research and Development Program of Zhejiang Province[2021C01180];University Development Fund[UDF01002665,CUHK-Shenzhen];the Research Initiation Fund Project from Zhejiang Sci-Tech University[22212012-Y];Zhejiang Provincial Natural Science Foundation of China under Grant No.LQ24F050005.
Bacteria-infected wounds healing has been greatly hindered by antibiotic resistance and persistent inflammation.It is crucial to develop multifunctional nanocomposites that possess effective antibacterial properties a...
supported by the National Natural Science Foundation of China(52173151,82002734,51803067);the Natural Science Foundation of Guangdong Province of China(2021A1515011084,2019A1515110312);the Fundamental Research Funds for the Central Universities(22qntd1302);the Shenzhen Outbound Postdoctoral Scientific Research Fund(SZBH202108).
Cartilage tissues possess an extremely limited capacity for self-repair,and current clinical surgical approaches for treating articular cartilage defects can only provide short-term relief. Despite significantadvances...
As we age,our skin loses elasticity and wrinkles form.To prevent this,most people try to improve skin wrinkles by performing procedures such as fillers,and absorbable lifting threads.Another way to solve this structur...
supported by research funding from the National Natural Science Foundation of China(82141130,82372735);the Sichuan Province Science and Technology Support Program(2019YJ0724,2023NSFSC1519);the China Postdoctoral Science Foundation(2022M712240);West China School/Hospital of Stomatology,Sichuan University(RCDWJS2022-10).
Head and neck squamous cell carcinoma(HNSCC)is the sixth most common malignant tumor worldwide.Considering its special anatomical site and the progressive resistance to chemotherapy drugs,the development of more effec...
supported by National Key Research and Development Program 2022YFC2409100;Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences[CIFMS,(no.2021-I2M-5-013)];111 Project[The Program of Introducing Talents of Discipline to Universities(no.B16033)].
Surgical repair with artificial chordae replacement has emerged asa standard treatment for mitral regurgitation. Expanded polytetrafluoroethylene (ePTFE) sutures are commonly employed asartificial chordae;however, the...
supported primarily by the National Natural Science Foundation of China(22075191,21774089,and 21935008);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Key Laboratory of Polymeric Materials Design and Synthesis for Biomedical Function,Soochow University;the Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application,Soochow University.
Surface endothelialization is a promising way to improve the hemocompatibility of biomaterials.However,current surface endothelialization strategies have limitations.For example,various surface functions are not well ...