《Oncology Research》

作品数:383被引量:139H指数:5
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《Oncology Research》
主办单位:Tech Science Press
最新期次:2025年5期更多>>
发文主题:RETRACTIONPROMOTESPROGRESSIONINVASIONPROLIFERATION更多>>
发文领域:医药卫生文化科学生物学自动化与计算机技术更多>>
发文基金:国家自然科学基金广东省自然科学基金重庆市自然科学基金北京市自然科学基金更多>>
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Death domain-associated protein(Daxx)impairs colon cancer chemotherapy by inhibiting the cGAS-STING pathway
《Oncology Research》2025年第5期1149-1159,共11页XI ZHU KAI HUANG XIAOMING KAO ZHAOHUI TANG WENJIE GUO TIANCONG WU QIURONG LI 
supported by the National Natural Science Foundation of China(82202956)。
Background:Colorectal cancer(CRC)holds the third position in global cancer prevalence mortality.Although chemotherapy is a conventional treatment,recent investigations have shed light on the therapeutic potential of t...
关键词:Death domain-associated protein(Daxx) Stimulator of the interferon gene(STING) Colorectal cancer(CRC) CHEMOTHERAPY 
Oncolytic adenovirus H101 enhances the anti-tumor effects of PD-1 blockade via CD47 downregulation in tumor cells
《Oncology Research》2025年第5期1161-1172,共12页CHENXIAO QIAO YIPENG XU YEDIE HE ZHIJIAN CAI HUA WANG 
supported by Techpool Bio-Pharma Co.,Ltd.(grant no.AKR-S005).
Objective:To investigate the anti-tumor effects of an E1B55KD-deleted oncolytic adenovirus,H101,in combination with a humanized anti-PD-1(Programmed cell death protein 1)monoclonal antibody,Camrelizumab.Methods:Anti-t...
关键词:Cancer Oncolytic adenovirus Macrophage CD47 Programmed cell death protein 1 blockade(PD-1 blockade) 
GlycoRNA:A new player in cellular communication
《Oncology Research》2025年第5期995-1000,共6页HYUNG SEOK KIM 
funded by the Korea Health Technology R&D Project through the Bio and Medical Technology Development Program of the National Research Foundation,supported by the Ministry of Science and ICT(RS-2023-00210847)and the Ministry of Education(RS-2024-00463331),Republic of Korea.
The discovery of glycosylated RNA molecules,known as glycoRNAs,introduces a novel dimension to cellular biology.This commentary explores the transformative findings surrounding glycoRNAs,emphasizing their unique roles...
关键词:GlycoRNA Cancer biology GLYCOSYLATION Immune evasion Therapeutic targets RNA modifications Lectin interactions 
The SS18-SSX fusion oncoprotein:Friend and foe in targeted therapy for synovial sarcoma
《Oncology Research》2025年第5期1001-1005,共5页GAVIN M.ANCHONDO KYRA PARKER ALEXIS BRUCE ELIZABETH CORTEZ LE SU 
Synovial sarcoma is a high-grade soft tissue malignancy characterized by a unique fusion gene known as SS18-SSX.The SS18-SSX fusion protein acts as an oncogenic driver of synovial sarcoma,and it has thus been commonly...
关键词:SS18-SSX Synovial sarcoma Targeted therapy 
Promising roles of vitamin D receptor and APRO family proteins for the development of cancer stem cells targeted malignant tumor therapy
《Oncology Research》2025年第5期1007-1017,共11页MOEKA NAKASHIMA NAOKO SUGA AKARI FUKUMOTO SAYURI YOSHIKAWA SATORU MATSUDA 
Malignant tumors are heterogeneous diseases characterized by uncontrolled cell proliferation,invasion,metastasis,and/or recurrence of their malignancies.In particular,cancer stem cells(CSCs)within these tumors might b...
关键词:Vitamin D Cancer stem cell INVASION METASTASIS CHEMORESISTANCE Ferroptosis Tumor microenvironment Noncoding RNAs Cancer therapy 
Current innovations in head and neck cancer:From diagnostics to therapeutics
《Oncology Research》2025年第5期1019-1032,共14页TAYYABA SATTAR IQRA NAZIR MEHREEN JABBAR JAVARIA MALIK SABA AFZAL SANA HANIF SEYED ALI MOSADDAD AHMED HUSSAIN HAMID TEBYANIYAN 
Background:Head and neck cancers(HNC)account for a significant global health burden,with increasing incidence rates and complex treatment requirements.Traditional diagnostic and therapeutic approaches,while effective,...
关键词:Head and neck cancer(HNC) DIAGNOSTICS THERAPEUTICS Innovations 
Non-coding RNAs as potential mediators of resistance to lung cancer immunotherapy and chemotherapy
《Oncology Research》2025年第5期1033-1054,共22页JIAHUI WANG HONGCHENG GE ZHENGYUAN YU LINGZHI WU 
Lung cancer is a common cause of cancer-related death globally.The majority of lung cancer patients initially benefit from chemotherapy and immunotherapy.However,as the treatment cycle progresses and the disease evolv...
关键词:Non-coding RNAs(ncRNAs) Lung cancer Drug resistance IMMUNOTHERAPY CHEMOTHERAPY Immune checkpoints Immune escape 
A review on pathobiology of circulating tumour plasma cells:The sine qua non of poor prognosis in plasma cell neoplasms
《Oncology Research》2025年第5期1055-1068,共14页PRATIBHA SUKU AISHWARYA DASH ARAVIND RADHAKRISHNAN PANKAJ MALHOTRA MAN UPDESH SINGH SACHDEVA 
Circulating plasma cells(CPCs)in patients of plasma cell neoplasm have been an area of intense research in recent decades.Circulating tumor plasma cells(CTPCs)might represent a sub-clone of tumor cells that have exite...
关键词:Circulating Plasma Cells(CPCs) Multiple Myeloma(MM) Flow cytometry Circulating Tumor Plasma Cells(CTPCs) Microenvironment Monoclonal gammopathy 
Classical biomarkers and non-coding RNAs associated with diagnosis and treatment in gastric cancer
《Oncology Research》2025年第5期1069-1089,共21页JINGDAN QUAN ZIXIN WAN WEI WU XINYUAN CAO JIAYUAN QIU XIAOYE LIU ZHIWEI ZHANG 
funded by the National Key Research and Development Project,grant number 2021YFE0192100;Natural Science Foundation of Hunan Province,grant numbers 2021JJ30694,2023JJ30529;Innovation and Entrepreneurship Training Program for College Students in Hunan Province,grant number S202210555254;Key Projects of Hunan Provincial Education Department,grant number 21A0285;Natural Science Foundation of Hunan Provincial and Municipal Co-Funding,grant number 2022JJ50029;Key Projects of Shaoyang Science and Technology Bureau,grant number 2021GZ031;Innovation and Entrepreneurship Training Program for College Students of the University of South China,grant numbers D202405212006326156,D202405210948392932,D202405211329047648,D202405221955420827.
One of the most prevalent malignant tumors worldwide,stomach cancer still has a high incidence and fatality rate in China,and the number of young people developing early-onset gastric cancer is steadily increasing.The...
关键词:Gastric cancer Biomarkers Immune checkpoint molecules Diagnosis MicroRNA CircRNA LncRNA PIRNA 
Research progress on cancer-associated fibroblasts in osteosarcoma
《Oncology Research》2025年第5期1091-1103,共13页LIWEN FENG YUTING CHEN WENYI JIN 
supported by the National Natural Science Foundation of China(grant number 81773285);Beijing Chao-Yang Hospital Golden Seeds Foundation(grant number CYJZ202341).
Osteosarcoma(OS)is a prevalent primary bone malignancy with limited treatment options.Therefore,it is imperative to investigate and understand the mechanisms underlying OS pathogenesis.Cancer-associated fibroblasts(CA...
关键词:Osteosarcoma(OS) Cancer-associated fibroblasts(CAFs) Tumor microenvironment(TME) Bone tumor 
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