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THERAPY: 作品数：3169被引量：9979H指数：32; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王飘王祖承钱铭怡李太生贾春生更多>>; 相关机构：首都医科大学第二军医大学复旦大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

Innovative gene delivery systems for retinal disease therapy: 《Neural Regeneration Research》2026年第2期542-552,共11页Hongguang Wu Ling Dong Shibo Jin Yongwang Zhao Lili Zhu; Hongguang Wu,Both authors contributed equally to this work and share first authorship;Ling Dong,Both authors contributed equally to this work and share first authorship;。; The human retina,a complex and highly specialized structure,includes multiple cell types that work synergistically to generate and transmit visual signals.However,genetic predisposition or age-related degeneration can...; 关键词：adeno-associated viruses delivery systems gene delivery gene therapy LENTIVIRUS nanoparticle delivery non-viral delivery retinal disease RETINA small molecular delivery

Biomaterial-based strategies:a new era in spinal cord injury treatment: 《Neural Regeneration Research》2025年第12期3476-3500,共25页Shihong Zhu Sijun Diao Xiaoyin Liu Zhujun Zhang Fujun Liu Wei Chen Xiyue Lu Huiyang Luo Xu Cheng Qiang Liao Zhongyu Li Jing Chen; supported by the Sichuan Science and Technology Program,No.2023YFS0164(to JC);the National Natural Science Foundation of China,No.82401629(to XL);the Natural Science Foundation of Sichuan Province,No.2024NSFSC1646(to XL);the China Postdoctoral Science Foundation,Nos.GZC20231811(to XL)and 2024T170601(to XL)。; Enhancing neurological recovery and improving the prognosis of spinal cord injury have gained research attention recently.Spinal cord injury is associated with a complex molecular and cellular microenvironment.This co...; 关键词：BIOMATERIALS growth factors NANOPARTICLES neural regeneration scaffolds spinal cord injury stem cells therapy strategies tissue engineering

Translational challenges in amyotrophic lateral sclerosis therapy with macrophage migration inhibitory factor: 《Neural Regeneration Research》2025年第9期2583-2584,共2页Leenor Alfahel Aleksandar Rajkovic Adrian Israelson; supported by grants from the Israel Science Foundation(ISF#284/19);German Israeli Foundation(GIF#I-116-415.6-2016)(to AI)。; Macrophage migration inhibitory factor(MIF):MIF acts as a pleiotropic inflammatory mediator,playing regulatory roles in innate and adaptive immunity,neuroinflammation,neuroendocrine functions,and nervous system develo...; 关键词：IMMUNITY SCLEROSIS

Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects: 《Neural Regeneration Research》2025年第8期2218-2230,共13页Rahul Mittal Keelin McKenna Grant Keith Evan McKenna Joana R.N.Lemos Jeenu Mittal Khemraj Hirani; Neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this condition.Diabetic peripheral neuropathy,a common complication of dia...; 关键词：diabetes mellitus diabetic peripheral neuropathy NEUROMODULATION neurostimulation therapy non-pharmacological treatment pain management

Insights into spinal muscular atrophy from molecular biomarkers被引量：1: 《Neural Regeneration Research》2025年第7期1849-1863,共15页Xiaodong Xing Xinzhu Liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing Xu Yan Liu Jian Zhang; supported by the Collaborative Innovation Center for Clinical and Translational Science by Chinese Ministry of Education&Shanghai,No.CCTS-2022205;the“Double World-Class Project”of Shanghai Jiaotong University School of Medicine(both to JZ)。; Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle weakness.It is one of the most common genetic causes of mortality among infants aged less than 2 years.Biomar...; 关键词：biomarkers disease progression gene-targeting therapy NEUROFILAMENTS Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

Emerging strategies for nerve repair and regeneration in ischemic stroke:neural stem cell therapy被引量：6: 《Neural Regeneration Research》2024年第11期2430-2443,共14页Siji Wang Qianyan He Yang Qu Wenjing Yin Ruoyu Zhao Xuyutian Wang Yi Yang Zhen-Ni Guo; supported by the National Natural Science Foundation of China,No.81971105(to ZNG);the Science and Technology Department of Jilin Province,No.YDZJ202201ZYTS677(to ZNG);Talent Reserve Program of the First Hospital of Jilin University,No.JDYYCB-2023002(to ZNG);the Norman Bethune Health Science Center of Jilin University,No.2022JBGS03(to YY);Science and Technology Department of Jilin Province,Nos.YDZJ202302CXJD061,20220303002SF(to YY);Jilin Provincial Key Laboratory,No.YDZJ202302CXJD017(to YY).; Ischemic stroke is a major cause of mortality and disability worldwide,with limited treatment options available in clinical practice.The emergence of stem cell therapy has provided new hope to the field of stroke trea...; 关键词：bystander effect cell replacement extracellular vesicles ischemic stroke neural stem cells neural stem cell engineering

Recent advances and future therapy development for Alzheimer’s disease and related disorders: 《Neural Regeneration Research》2024年第9期1877-1878,共2页Megan Hong Gal Bitan; supported by NIH grants RF1NS126406 and R21NS130326;by a generous gift from the Binder Foundation (to GB); Over 55 million people globally live with Alzheimer’s disease(AD)or related dementias(ADRD)and the number is expected to double every twenty years.Unt i l recent l y,onl y symptomatic treatments were available to pat...; 关键词：ALZHEIMER globally patients

MAP4K inhibition as a potential therapy for amyotrophic lateral sclerosis被引量：1: 《Neural Regeneration Research》2024年第8期1639-1640,共2页Shuaipeng Ma Chun-Li Zhang; supported by the TARCC,Welch Foundation Award(1-1724);the Decherd Foundation,the Pope Adarms Foundation;NIH grants NS092616,NS127375,NS117065,and NS111776(to CLZ)。; Amyotrophic lateral sclerosis(ALS)is a rare neurological disease,featuring gradual loss of muscle controls due to degeneration of motor neurons.Unfortunately,there is currently no cure for ALS.The available therapies ...; 关键词：DEGENERATION SCLEROSIS MAP4

Long non-coding RNAs with essential roles in neurodegenerative disorders: 《Neural Regeneration Research》2024年第6期1212-1220,共9页Wandi Xiong Lin Lu Jiali Li; supported by the National Natural Science Foundation of China,Nos.91649119 and 92049105(both to JL)。; Recently,with the advent of high-resolution and high-throughput sequencing technologies,an increasing number of long non-coding RNAs(lncRNAs)have been found to be involved in the regulation of neuronal function in the...; 关键词：Alzheimer's disease amyotrophic lateral sclerosis BIOMARKER Huntington's disease long non-coding RNAs neurodegenerative diseases Parkinson's disease THERAPY transcriptional regulation translational regulation

Learning to become addicted,one synapse at a time: 《Neural Regeneration Research》2024年第2期401-402,共2页Alessio Attardo Sidney B.Cambridge; Addiction has been extensively studied on many levels:from the molecular level,with various“omics”approaches(Natividad et al.,2018;Grecco et al.,2021),to the clinical level,with psychotherapy and MRI imaging(Ceceli ...; 关键词：CLINICAL THERAPY

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