supported by the Intramural Research Program of the National Institutes of Health,the National Cancer Institute,and the Center for Cancer Research(ZIASC010357 to Z.M.Z.).
Plasmid DNA transfection is one of the fundamental tools of biomedical research.Here,we found that plasmid DNA transfection mediated by liposomes activates multiple innate immune responses in several widely used cell ...
funded by the Indiana Clinical and Translational Science Institute and Showalter Trust (to Uma K. Aryal);the Human Resources Program in Energy Technology of the Korea Institute of Energy Technology Evaluation and Planning (20214000000140 (to HeeChang Lim));the National Institutes of Health R35GM147412 (to Jing Liu) and R01AR074473 (to William R. Thompson);the National Natural Science Foundation of China, 81971326 (to Bai-Yan Li);the 100 Voices of Hope (to Hiroki Yokota)。
Bone frequently serves as a metastatic site for breast and prostate cancers. Given the potential of low-intensity vibration(LIV) to increase bone health and reduce cancer risk, this study investigated the impact of LI...
supported by the grants from the National Natural Science Foundation of China(Nos.82173177 and 82103429).
Lung adenocarcinoma(LUAD)remains a predominant cause of cancer-related mortality globally,underscoring the urgency for targeted therapeutic strategies.The specific role and impact of the SEC61 translocon gamma subunit...
National Natural Science Foundation of China,Grant/Award Numbers:82372943,82303610;Hunan Provincial Natural Science Foundation of China,Grant/Award Number:2022JJ20095;Hunan Youth Science and Technology Talent Project,Grant/Award Number:2023RC3074;China Postdoctoral Science Foundation,Grant/Award Number:2023MD734131;Chongqing Postdoctoral Science Foundation,Grant/Award Number:CSTB2023NSCQBHX0002;Kuanren Talents Program of the second affiliated hospital of Chongqing Medical University;Chongqing Postdoctoral Research Special Funding Project,Grant/Award Number:2023CQBSHTB3095。
The intratumoral microbiome(TM)refers to the microorganisms in the tumor tissues,including bacteria,fungi,viruses,and so on,and is distinct from the gut microbiome and circulating microbiota.TM is strongly associated ...
supported by the Natural Science Foundation of Sichuan Province(2022NSFSC0774);the Sichuan Science and Technology Regional Collaboration Project(2023YFQ0012).
Cardiac myxoma is a commonly encountered tumor within the heart that has the potential to be life-threatening.However,the cellular composition of this condition is still not well understood.To fill this gap,we analyze...
Cancer is a major cause of morbidity and mortality worldwide,and the incidence is increasing,highlighting the need for effective strategies to treat this disease.Exercise has emerged as fundamental therapeutic medicin...
National Natural Science Foundation of China,Grant/Award Numbers:82373275,81974384,82173342,82203015;China Postdoctoral Science Foundation,Grant/Award Number:2023JJ40942;Nature Science Foundation of Hunan Province,Grant/Award Numbers:2021JJ3109,2021JJ31048,2023JJ40942;Nature Science Foundation of Changsha,Grant/Award Number:73201;CSCO Cancer Research Foundation,Grant/Award Numbers:Y-HR2019-0182,Y-2019Genecast-043;the Key Research and Development Program of Hainan Province,Grant/Award Numbers:ZDYF2020228,ZDYF2020125。
Significant developments in cancer treatment have been made since the advent of immune therapies.However,there are still some patientswithmalignant tumors who do not benefit from immunotherapy.Tumors without immunogen...
supported by funding from the Swiss National Science Foundation(SNSF Grant No.310030-215237/1);the Schoenmakers-Müller Foundation,a research grant from Ono Pharmaceuticals,and the Cancer League of Basel(KlbB).Open access funding provided by University of Basel.
The overexpression of sialic acids on glycans,called hypersialylation,is a common alteration found in cancer cells.Sialylated glycans can enhance immune evasion by interacting with sialic acid-binding immunoglobulin-l...
The global incidence of lung cancer is marked by a considerably elevated mortality rate.MicroRNAs(miRNAs)exert pivotal influence in the intricate orchestration of gene regulation,and their dysregulation can precipitate...
supported by Shanghai Shenkang Hospital Development Center(No.SHDC12019X38).
Through bioinformatics predictions,we identified that GTF2I and FAT1 were downregulated in thyroid carcinoma(TC).Further,Pearson’s correlation coefficient revealed a positive correlation between GTF2I expression and ...