ATHEROGENESIS

作品数：28被引量：85H指数：5
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相关机构：南京军区总医院北京大学更多>>
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Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis
《Research》2024年第2期123-137,共15页Di Xiang Lei Jiang Qiong Yuan Yang Yu Ruiming Liu Meiting Chen Zheng Kuai Wendy Zhang Fan Yang Tingting Wu Zhiyu He Zuhui Ke Wanzi Hong Pengcheng He Ning Tan Yeying Sun Zhen Shi Xuebiao Wei Jianfang Luo Xiaoqiu Tan Yuqing Huo Gangjian Qin Chunxiang Zhang 
supported by the National Natural Science Foundation of China(Grant Nos.82030007,81670398,and 91639102);the Central Government Guides Local Science and Technology Development Project(Grant No.2022ZYD0057);the Sichuan Science and Technology Program(Grant Nos.2022YFS0578 and 2022YFS0614);the Start-up Research Fund of Southwest Medical University(Grant No.00040155);supported in part by the Start-up fund from the University of Alabama at Birmingham.
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis.Long non-coding RNAs(lncRNAs)are a group of protein ...
关键词：inhibited MOR markedly 
Sortilin-induced lipid accumulation and atherogenesis are suppressed by HNF1b SUMOylation promoted by flavone of Polygonatum odoratum
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第11期998-1013,共16页Fang LIU Shirui CHEN Xinyue MING Huijuan LI Zhaoming ZENG Yuncheng LV 
supported by the Natural Science Foundation of Guangxi Zhuang Autonomous Region,China (No.2019JJA140728);the Horizontal Cooperation Project with Hunan Mingshun Pharmaceutical Co.,Ltd. (No.2021GLHX02);the Guangxi Province Postgraduate Co-training Base for Cooperative Innovation in Basic Medicine of Guilin Medical University (No.Gui Xue Wei[2020]7).
This study aims to investigate the impact of hepatocyte nuclear factor 1β(HNF1b)on macrophage sortilin-mediated lipid metabolism and aortic atherosclerosis and explore the role of the flavone of Polygonatum odoratum(...
关键词：ATHEROSCLEROSIS Lipid accumulation Hepatocyte nuclear factor 1β(HNF1b) Flavone of Polygonatum odoratum SUMOYLATION 
lncR-GAS5 upregulates the splicing factor SRSF10 to impair endothelial autophagy,leading to atherogenesis被引量：4
《Frontiers of Medicine》2023年第2期317-329,共13页Yuhua Fan Yue Zhang Hongrui Zhao Wenfeng Liu Wanqing Xu Lintong Jiang Ranchen Xu Yue Zheng Xueqing Tang Xiaohan Li Limin Zhao Xin Liu Yang Hong Yuan Lin Hui Chen Yong Zhang 
supported,in part,by the National Natural Science Foundation of China(Nos.81773735,81973313,and 81503069);the National Key R&D Program of China(No.2017YFC1702003);the Natural Science Foundation of Heilongjiang Province(No.ZD2022H002);the Fundamental Research Funds for the Provincial Universities-Academician Mr.Yu Weihan Foundation for Distinguished Young Scholars(No.JFYWH202001).
Long noncoding RNAs(lncRNAs)play a critical role in the regulation of atherosclerosis.Here,we investigated the role of the lncRNA growth arrest-specific 5(lncR-GAS5)in atherogenesis.We found that the enforced expressi...
关键词：lncR-GAS5 miR-193-5p splicing factor SRSF10 AUTOPHAGY ATHEROGENESIS 
Advances in research of Apo C-Ⅲ and Coronary Atherosclerosis Heart Disease
《South China Journal of Cardiology》2022年第2期103-110,共8页YU Jin-jin ZHU Ping PAN Wei 
Coronary atherosclerotic heart disease had been regarded as the leading killer of human being.The atherosclerotic lesion would cause blood flow blockage or lumen stenosis of coronary arteries,thus resulting in myocard...
关键词：Apo C-Ⅲ Coronary atherosclerosis heart disease ATHEROGENESIS 
Autophagy enhanced by curcumin ameliorates inflammation in atherogenesis via the TFEB-P300-BRD4 axis被引量：14
《Acta Pharmaceutica Sinica B》2022年第5期2280-2299,共20页Xuesong Li Ruigong Zhu Hong Jiang Quanwen Yin Jiaming Gu Jiajing Chen Xian Ji Xuan Wu Haiping Fu Hui Wang Xin Tang Yuanqing Gao Bingjian Wang Yong Ji Hongshan Chen 
supported by grants from the National Natural Science Foundation of China (31771334,81970428 and 81800385);the Key Research Plan of the National Natural Science Foundation of China (81820108002);the Major Research Plan of the National Natural Science Foundation of China (91649125 and 91639204);University Natural Science Research of Jiangsu Province (18KJB310008,China);Jiangsu Province Health and Family Planning Commission Scientific Research Project (H2017011,China);Jiangsu Provincial Medical Youth Talent (QNRC2016432,China);Top Talents Project Foundation of “Six-One Project” for High-level Health Talents of Jiangsu Province (LGY2020055,China);Technology Development Foundation of Nanjing Medical University (2017NJMUZD020,China);supported by the program of special professor of Jiangsu Province,the program of the special medical experts of Jiangsu Province and the program of innovation and entrepreneurship team plan of Jiangsu Province,China。
Disturbance of macrophage-associated lipid metabolism plays a key role in atherosclerosis.Crosstalk between autophagy deficiency and inflammation response in foam cells(FCs) through epigenetic regulation is still poor...
关键词：MACROPHAGE AUTOPHAGY TFEB P300 BRD4 INFLAMMATION Atherosclerosis CURCUMIN 
Diabetic patients with chronic kidney disease: Non-invasive assessment of cardiovascular risk被引量：2
《World Journal of Diabetes》2021年第7期975-996,共22页Nejc Piko Sebastjan Bevc Robert Ekart Tadej Petreski Nina Vodošek Hojs Radovan Hojs 
The prevalence and burden of diabetes mellitus and chronic kidney disease on global health and socioeconomic development is already heavy and still rising.Diabetes mellitus by itself is linked to adverse cardiovascula...
关键词：Diabetes mellitus Diabetes complications Chronic kidney disease ATHEROGENESIS ATHEROSCLEROSIS Cardiovascular risk 
The Configuration of the Femoral Arterial Bifurcation’s Influence on Its Atherogenesis被引量：1
《Forensic Medicine and Anatomy Research》2020年第2期45-53,共9页Magaye Gaye Papa Adama Dieng Ainina Ndiaye Racky Wade Sidy Diop Ndeye Fatou Sow Papa Amath Diagne Souleymane Diatta Salmane Ba Mourad Boufi Assane Ndiaye Amadou Gabriel Ciss Abdoulaye Ndiaye 
Several theories point to the influence of the geometry of femoral arterial bifurcation in the formation and evolution of atherosclerosis plaques at the level of common, superficial and deep femoral arteries. The obje...
关键词：TORTUOSITY CALCIFICATION Atherosclerosis FEMORAL ARTERIAL Bifurcation 
Atherogenic Diet Accelerates Ectopic Mineralization in a Mouse Model of Pseudoxanthoma Elasticum
《International Journal of Dermatology and Venereology》2020年第2期91-96,共6页Zhao Jing-Yi Kingman Joshua Jacobs Ida Joely Uitto Jouni Cao Yi Li Qiao-Li 
This study was supported by National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases grants(No.R01AR055225 to JU,K01AR064766 to QL,and R01AR072695 to JU and QL).
Objective:Pseudoxanthoma elasticum(PXE)is a multisystem heritable disorder caused by mutations in the Abcc6 gene.The disease is characterized by ectopic mineralization of the skin,eyes,and arterial blood vessels.Previ...
关键词：pseudoxanthoma elasticum ectopic mineralization ATHEROGENESIS mouse model 
Catechins Green Tea GMB4 Clone Increases mRNA of ABCA1 through LXR Signaling in Cultured Macrophage Exposed OX-LDL
《Food and Nutrition Sciences》2019年第9期1179-1190,共12页Erna Susanti Retty Ratnawati Aulanni’am Aulanni’am Achmad Rudijanto 
Inhibition of atherogenesis through inhibition of lipid metabolism has not been explored while other inhibitions through inflammation, endothelial dysfunction and free radicals have done. Inhibition of atherogenesis v...
关键词：ATHEROGENESIS CATECHINS ABCA1 ABCG1 Dan SRB1 CULTURED MACROPHAGE 
Impact of Connexins on Atherogenesis: A Brief Review
《Journal of Integrative Medicine（双语）》2018年第2期12-19,共8页Veronika A. Myasoedova Dongwei Zhang Reinhard Wetzker Andrey V. Grechko Alexander N. Orekhov 
the Russian Science Foundation (Grant # 18-15-00254).
Connexins family in humans consists of 21 highly conserved proteins that are responsible for contact formation between cells. On the cell surface, connexins form hemichannels, or connexons. Two hemichannels brought to...
关键词：CONNEXIN Connexon Gap JUNCTION ATHEROSCLEROSIS VASCULAR wal 
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