GALANGIN

作品数：8被引量：36H指数：2
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相关领域：医药卫生更多>>
相关作者：李建磊李修成何伟钱宇韩维奇更多>>
相关机构：绍兴市人民医院芜湖市第二人民医院山西医科大学南京医科大学更多>>
相关期刊：《Asian Pacific Journal of Tropical Biomedicine》《World Journal of Gastroenterology》《Journal of Polyphenols》《Journal of Hainan Medical University》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Galangin mitigates glucocorticoid-induced osteoporosis by activating autophagy of BMSCs via triggering the PKA/CREB signaling pathway被引量：1
《Acta Biochimica et Biophysica Sinica》2023年第8期1275-1287,共13页Chenying Zeng Shan Wang Huimin Gu Fenglei Chen Ziming Wang Jinteng Li Zhongyu Xie Pei Feng Huiyong Shen Yanfeng Wu 
supported by the grants from the National Natural Science Foundation of China(Nos.82172349 and 82172385);the Shenzhen Key Laboratory of Ankylosing Spondylitis(No.ZDSYS20190902092851024).
Glucocorticoid-induced osteoporosis(GIOP),one of the most common and serious adverse effects associated with glucocorticoid administration,manifests as decreased bone formation and increased bone resorption,eventually...
关键词：GALANGIN glucocorticoid-induced osteoporosis DEXAMETHASONE BMSC AUTOPHAGY 
Galangin probably ameliorates hyperuricemia by inhibiting urate acid transport 1 (URAT1): Homology modeling and mechanism exploration
《Journal of Polyphenols》2022年第1期55-63,共9页Aijinxiu Ma Fuqi Wang Xu Zhao 
This work was supported by Young and Middle Aged Teachers’Career Development Support Project of Shenyang Pharmaceutical University(ZQN2019005).
Urate acid transporter 1(URAT1)is the main transporter of uric acid reabsorption,which closely related to the pathogenesis of hyperuricemia.Screening URAT1 inhibitors and studying their possible metabolic processes is...
关键词：plant polyphenols GALANGIN URAT1 HYPERURICEMIA homology modeling 
Prescription optimization and characterization of Galangin-PLGA nanoparticles
《Journal of Hainan Medical University》2021年第11期8-13,共6页Ying-Zi Chen Rong Zhu Xu-Yi Sun Xin-Fu Wu Yu Zhang Yu-Ying Yang Na Wei Zhen-Miao Qin 
National natural science foundation of China(No.81660649);Innovation and entrepreneurship training program for undergraduates of Hainan medical university in 2019(No.X201911810073)。
Objective:To make Galangin-PLGA nanoparticles(GL-PLGA NPs)were prepared using the biodegradable material polylactic-coglycolic acid(PLGA)as the carrier material,and the formulation was optimized.Methods:Nanoparticles ...
关键词：GALANGIN Polylactic-coglycolic acid NANOPARTICLES Orthogonal test 
Galangin ameliorates changes of membrane-bound enzymes in rats with streptozotocin-induced hyperglycemia
《Asian Pacific Journal of Tropical Biomedicine》2019年第7期284-290,共7页Amal A.Aloud Chinnadurai Veeramani Chandramohan Govindasamy Mohammed A.Alsaif Khalid S.AlNumair 
Objective: To assess the protective effect of galangin on membrane bound enzymes in rats with streptozotocin-induced diabetes. Methods: A single low dose of streptozotocin was injected to adult male albino rats to ind...
关键词：STREPTOZOTOCIN HYPERGLYCEMIA Sodium-potassium-ATPase Calcium-ATPase Magnesium-ATPase GALANGIN 
Analysis of potential amino acid biomarkers in brain tissue and the effect of galangin on cerebral ischemia
《中国药理学与毒理学杂志》2015年第S1期46-47,共2页JianGAO ChangCHEN Fei-pengDUAN JingFANG Shao-jingLI 
The project supported by National Natural Science Foundation of China(81303261,81274133);the Major Scientific and Technological Special Project for″Significant New Drugs Creation″(2012ZX09103-201-055);the Fundamental Research Funds for the Central public welfare research institutes of China(ZZ2014005,ZZ2014060)
OBJECTIVE Galangin,apotent scavenger of free radicals,is used as herbal medicine for various ailments for centuries in Asia.With complex pathophysiology,ischemic stroke is one of the most frequent causes of death and ...
关键词：GALANGIN AMINO acid biomarkers CEREBRAL ISCHEMIA b 
Galangin and TRAIL cooperate to suppress A549 lung cancer proliferation via apoptosis and p38 MAPK activation被引量：4
《Acta Pharmaceutica Sinica B》2012年第6期569-574,共6页Wenjing Zhang Qilai Huang Zichun Hua 
This study was supported,in part,by the Science and Technology Development Fund of the Macao Special Administrative Region(Nos.071/2009/A3 and 091/2009/A);the National Key Basic Research Project from the Chinese Ministry of Science and Technology(2012CB967004);the Chinese National Nature Sciences Foundation(81121062,50973046,31070706);the Jiangsu Provincial Nature Science Foundation(BK2010046,BZ2010074,BZ2011048,BK2011228,BZ2011048);the Bureau of Science and Technology of Changzhou(CN20100016,CZ20100008,CE20115034,CZ20110028).
Tumor necrosis factor-related apoptosis inducing ligand(TRAIL)is a promising antitumor therapy against lung cancer which is currently undergoing a phase II clinical trial in China.Unfortunately some cancer patients in...
关键词：GALANGIN TRAIL A549 cellline Cytotoxicity APOPTOSIS P38 MAPK 
Galangin induces apoptosis of hepatocellular carcinoma cells via the mitochondrial pathway被引量：32
《World Journal of Gastroenterology》2010年第27期3377-3384,共8页Hai-Tao Zhang  Liu-Bo Lan  Da-Hua Fan  Kai-Dan Zhu  Xiao-Yi Chen  Min Wen  Hui-Ming Liu Guangdong Province  China Hui Luo 
Supported by The administration of traditional Chinese medicine of Guangdong province,China,No.1050047
AIM:To investigate the mechanism by which galangin,a polyphenolic compound derived from medicinal herbs,induces apoptosis of hepatocellular carcinoma(HCC) cells.METHODS:The 3-(4,5-Dimethyl-thiazol-2-yl)-2,5-diphenyl-t...
关键词：Hepatocellular carcinoma GALANGIN MITOCHONDRIA BCL-2 APOPTOSIS 
Flow-injection chemiluminescence determination of tryptophan using galangin-potassium permanganate-polyphosphoric acid system被引量：2
《Chinese Chemical Letters》2008年第2期203-206,共4页Hui Chen Li Li Min Zhou Yong Jun Ma 
A high sensitive flow-injection chemiluminescence （FI-CL） method for the determination of tryptophan has been developed. The method is based on the chemiluminescence reaction of galangin-potassium permanganate-trypt...
关键词：CHEMILUMINESCENCE FLOW-INJECTION GALANGIN Potassium permanganate TRYPTOPHAN 
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