National Natural Science Foundation of China,No.81873934;and Jinan Science and Technology Planning Project,No.202225065.
BACKGROUND Mesenchymal stem cells,found in various tissues,possess significant healing and immunomodulatory properties,influencing macrophage polarization,which is essential for wound repair.However,chronic wounds pre...
Supported by Science and Technology Department Project of Jilin Province,China,No.20230101163JC;the Outstanding Youth Fund Project of Jilin Provincial Department of Education,China,No.JJKH20241324KJ.
Coronavirus disease 2019(COVID-19)is an acute respiratory infection caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).SARS-CoV-2 infection typically presents with fever and respiratory symptoms,whi...
Supported by the National Natural Science Foundation of China,No.81871568,No.32100643;COVID-19 Infection and Prevention Emergency Special Project of Chongqing Education Commission,No.KYYJ202009.
BACKGROUND The immunosuppressive capacity of mesenchymal stem cells(MSCs)is dependent on the“license”of several proinflammatory factors to express immunosuppressive factors such as programmed cell death 1 ligand 1(P...
Supported by National Natural Science Foundation of China,No.82074533.
Ischemic stroke(IS)is the most prevalent form of brain disease,characterized by high morbidity,disability,and mortality.However,there is still a lack of ideal prevention and treatment measures in clinical practice.Not...
BACKGROUND Sustained injury,through radiotherapy,burns or surgical trauma,can result in fibrosis,displaying an excessive deposition of extracellular matrix(ECM),persisting inflammatory reaction,and reduced vasculariza...
Supported by the National Natural Science Foundation of China,No.81670444;and the CAMS Innovation Fund for Medical Sciences(CIFMS),No.2020-I2MC&T-A-004.
Fibrosis is the hyperactivation of fibroblasts that results in excessive accumulation of extracellular matrix,which is involved in numerous pathological changes and diseases.Adipose-derived stem cells(ASCs)are promisi...
Fundo de IncentivoàPesquisa e Eventos(Fipe)-Hospital de Clínicas de Porto Alegre,No.GPPG 2017-0004.
Mesenchymal stromal cells (MSCs) are multipotent and self-renewing stem cellsthat have great potential as cell therapy for autoimmune and inflammatorydisorders, as well as for other clinical conditions, due to their i...
The therapeutic value of mesenchymal stem cells (MSCs) for the treatment of infectious diseases and the repair of disease-induced tissue damage has been explored extensively. MSCs inhibit inflammation, reduce pathogen...
Supported by the Project Contract for Technical Innovation Project for Small and Medium-sized Science and Technology Enterprises in Jiangning District,No.2020JSCX0563.
Pneumonia is the inflammation of the lungs and it is the world’s leading cause of death for children under 5 years of age.The latest coronavirus disease 2019(COVID-19)virus is a prominent culprit to severe pneumonia....
Umbilical cord blood(UCB)is a primitive and abundant source of mesenchymal stem cells(MSCs).UCB-derived MSCs have a broad and efficient therapeutic capacity to treat various diseases and disorders.Despite the high lat...