QUINIDINE

作品数:15被引量:35H指数:3
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相关领域:医药卫生更多>>
相关作者:周鹏杨新春郭东林胡崇家曾繁典更多>>
相关机构:首都医科大学附属北京朝阳医院首都医科大学同济医科大学更多>>
相关期刊:《Open Journal of Veterinary Medicine》《Acta Pharmacologica Sinica》《Science China Chemistry》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金更多>>
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Pharmacological Treatment for Atrial Fibrillation—Modalities in Equines and Companion Animals
《Open Journal of Veterinary Medicine》2024年第10期257-303,共47页Ina Cojoaca 
Cardiac arrhythmias are probably more common in horses than in any other domestic animal species where poor performance and exercise intolerance is the most frequent clinical complaint. Atrial fibrillation is a type o...
关键词:Atrial Fibrillation ARRYTHMIA Equine Cardiology Poor Performance Pharmacological Treatment QUINIDINE Genetic Predisposition Sinus Rhythm 
Deuterated dextromethorphan/quinidine for agitation in Alzheimer's disease
《Neural Regeneration Research》2022年第5期1013-1014,共2页Rita Khoury 
Alzheimer's disease(AD)is the most common type of neurode generative disorder;it affects around 47 million individuals worldwide(Prince et al.,2013).AD rose from the 12 th most burdensome disease in the United States ...
关键词:ALZHEIMER AGITATION 
Pathogenesis and drug response of iPSC-derived cardiomyocytes from two Brugada syndrome patients with different Nav1.5-subunit mutations
《The Journal of Biomedical Research》2021年第5期395-407,I0004-I0007,共17页Yue Zhu Linlin Wang Chang Cui Huiyuan Qin Hongwu Chen Shaojie Chen Yongping Lin Hongyi Cheng Xiaohong Jiang Minglong Chen 
supported by the Natural Science Foundation of Jiangsu Province of China(Grant No.BK20160134 to LW and BK20191071 to CC);National Natural and Science Foundation of China(Grant No.81900295 to CC);Special Foundation for Clinical Science and Technology of Jiangsu Province(Grant No.BE2017754 to HWC).
Brugada syndrome(BrS)is a complex genetic cardiac ion channel disease that causes a high predisposition to sudden cardiac death.Considering that its heterogeneity in clinical manifestations may result from genetic bac...
关键词:human iPSCs Brugada syndrome disease modeling QUINIDINE SCN5A SCN1B 
Evidence for using dextromethorphan-quinidine for the treatment of agitation in dementia
《World Journal of Psychiatry》2020年第4期29-33,共5页Rajesh R Tampi Pallavi Joshi Padmapriya Marpuri Deena J Tampi 
Behavioral and psychological symptoms including agitation are common in dementia,and are associated with decreased quality of life,increased risk of institutionalization,and greater patient and caregiver distress.Phar...
关键词:DEXTROMETHORPHAN QUINIDINE AGITATION DEMENTIA Behavioral and psychological SYMPTOMS of DEMENTIA 
Determination of L-norvaline and L-tryptophan in dietary supplements by nano-LC using an O-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11- dihydroquinidine-silica hybrid monolithic column被引量:1
《Journal of Pharmaceutical Analysis》2020年第1期70-77,共8页Dongsheng Xu Elena Sanchez-Lopez Qiqin Wang Zhengjin Jiang María Luisa Marina 
An analytical methodology based on an O-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11-dihydroquinidine(MQD)-silica hybrid monolithic column was developed for the enantioseparation of 9-fluorenylmethoxycarbonyl(FMOC)deriv...
关键词:9-Fluorenylmethoxycarbonyl Amino acids Chiral separation NANO-LC Quinidine-silica hybrid monolithic column 
Interaction of Iron(III)-5,10,15,20-Tetrakis (4-Sulfonatophenyl) Porphyrin with Chloroquine, Quinine and Quinidine
《Crystal Structure Theory and Applications》2017年第3期25-38,共14页Dikima D. Bibelayi Pitchouna I. Kilunga Albert S. Lundemba Matthieu K. Bokolo Pius T. Mpiana Philippe V. Tsalu Juliette Pradon Colin C. Groom Celine W. Kadima Luc Van Meervelt Zephyrin G. Yav 
Iron(III)-5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin (FeTPPS) is used as non-physiological metalloporphyrin model for the natural iron (III)-protoporphyrin IX (FePPIX) resulting from hemoglobin degradation to in...
关键词:FeTPPS Apparent Binding Constant (K) Molecular Electrostatic Potential (MEP) CAMBRIDGE Structural Database (CSD) 
Modulation of the pentose phosphate pathway alters phase I metabolism of testosterone and dextromethorphan in HepG2 cells被引量:3
《Acta Pharmacologica Sinica》2015年第2期259-267,共9页Wen-jing XIAO Ting MA Chun GE Wen-juan XIA Yong MAO Run-bin SUN Xiao-yi YU Ji-ye AA Guang-ji WANG 
Aim: The pentose phosphate pathway (PPP) is involved in the activity of glucose-6-phosphate dehydrogenase (G6PD) and generation of NADPH, which plays a key role in drug metabolism. The aim of this study was to in...
关键词:drug metabolism HepG2 cells pentose phosphate pathway G6PD p53 CYP TESTOSTERONE DEXTROMETHORPHAN KETOCONAZOLE QUINIDINE cyclic PFT-a NSC 66811 6-aminonicotinamide MENADIONE 
Charge-transfer interaction of drug quinidine with quinol,picric acid and DDQ: Spectroscopic characterization and biological activity studies towards understanding the drug–receptor mechanism
《Journal of Pharmaceutical Analysis》2014年第2期81-95,共15页Hala H.Eldaroti Suad A.Gadir Moamen S.Refat Abdel Majid A.Adam 
Investigation of charge-transfer (CT) complexes of drugs has been recognized as an important phenomenon in understanding of the drug-receptor binding mechanism. Structural, thermal, morpholo-gical and biological beh...
关键词:QUINIDINE Charge-transfer interac-tion Powder X-ray diffractionMorphology Thermal analysis 
Gold nanoparticles based digital color analysis for quinidine detection被引量:2
《Chinese Science Bulletin》2013年第18期2027-2032,共6页ZOU BoZhou LIU Yue YAN XiaoLi HUANG ChengZhi 
supported by the National Natural Science Foundation of China (21035005);the National Special Major Project of Science and Technology for Creation of New Drugs (20102X09401-306-1-4)
In this contribution,we developed a novel digital color analysis of gold nanoparticles(AuNPs) for pharmaceutical detection by choosing quinidine as an example.It was found that the color of AuNPs colloid solution chan...
关键词:金纳米粒子 数字彩色 检测分析 基础 胶体溶液 颜色信息 药品检测 最佳条件 
Effects of Matrine on Aconitine-Induced Electrophysiological Changes in Rat Ventricular Myocytes被引量:19
《Journal of Chinese Pharmaceutical Sciences》2004年第3期193-198,共6页SHANHong-li YANGBao-feng ZHOUYu-hong WANGHe LIBao-xin 
NationalNaturalScienceFoundationofChina(30271599),
Aim To explore the reason that the antiarrhythmic effect of the extract oftraditional Chinese medicinal herb, matrine, is weaker than quinidine and verapamil by comparison ofthe effect and efficacy of matrine on vario...
关键词:ARRHYTHMIAS MATRINE QUINIDINE VERAPAMIL ion channel 
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