supported by grants to S.C.L.from the Swee Liew-Wadsworth Endowment fund,National University of Singapore(NUS),Ministry of Education(MOE-T2EP30220-0014),Singapore;the National Research Foundation(NRF-ISF003-3221),Singapore;grants to H.M.S.from University of Macao(CPG2023-0032FHS and UM-MYRG2020-00022-FHS);Macao Science and Technology Development Fund(FDCT0078/2020/A2,FDCT0031/2021/A1,FDCT0081/2022/AMJ,and FDCT 0004/2021/AKP);supported by the NUS Graduate School Research Scholarships.
Glucose-6-phosphate dehydrogenase(G6PD)is the rate-limiting enzyme in the pentose phosphate pathway(PPP)in glycolysis.Glucose metabolism is closely implicated in the regulation of mitophagy,a selective form of autopha...