相关期刊:《Journal of Pharmaceutical Analysis》《Asian Pacific Journal of Tropical Medicine》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》更多>>
Objective:To explore the anti-tumor effects of asiatic moonseed rhizome extraction-dauricine on bladder cancer EJ cell strain,prostate cancer PC-3Mcell strain and primary cell culture system.Methods:The main effective...
Acknowledgements This work was supported by the grants from the National Natural Science Foundation of China (No 30872944), the Guangdong Administration of Traditional Chinese Medicine (No 2008166), and the Department of Science and Technology of Dongguan (No 2008108101029). We thank Prof Xiong-tai GUAN (Guangdong Medical College, Zhanjiang, China) for kindly providing Dau. We also thank Dr Anh D Le and Dr Qun-zhou ZHANG (Center for Craniofacial Molecular Biology, School of Dentistry, University of Southern California, Los Angeles, USA) for their technical assistance and strong support.
Aim: To investigate the effects of dauricine (Dau) on insulin-like growth factor-Ⅰ (IGF-Ⅰ)-induced hypoxia inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) expression in human br...
Project supported by the Scientific Research Foundation of Committee of Science and Technology of Hubei Province. №991P1609.
AIM: To study the combined pharmacokinetic-pharmacodynamic(PK-PD) model of daurisoline and dauricine, and compare their effects on cardiac electrophsiology, blood pressure, and hemodynamics in beagle dogs. METHODS: Th...
Project supported by Scientific Foundation of Ministry of Health of China,№ 96-1-134.
Tetrandrine, dauricine, daurisoline and neferine are bisbenzylisoquinoline alkaloid derivatives isolated from Chinese traditional medicine and herbs. The cardiovascular pharmacological effects and the mechanism of act...
Project supported by the National Natural Science Foundation of China, № 39670834.
AIM: To study the effects of dauricine and sotalol on monophasic action potentials and effective refractory period of the rabbit heart in situ. METHODS: Monophasic action potentials recording and programmed electrical...
This project was suported by a grant from the foundation of Youth Sciences and Technology Chenguang Planning ofWuhan (No.2 0
To study the metabolism of dauricine in vivo and in vitro and identify the structure of its main metabolites, urine of rats after drug administration as the samples of dauricine metabolism in vivo was studied. Rat liv...
Summary: To establish the determination method of dauricine (Dan) concentration in rats' blood and other biological samples, a reverse-phase HPLC method was adopted. Under the given condition, dauricine could be well...
Project supported by the National Natural Science Foundation of China. No 39670834.
AIM: To study the effects of dauricine(Dau) on the rapidly activating component (Ikr), the slowly activating component (Iks) of the delayed rectifier potassium current, and the inward rectifier potassium current (Ikl)...
Intravenous injection of platelet agonists ADP and thrombin induced the accumulation of 111 In labelled platelets within the pulmonary vasculature. Pretreatment with i.v. administration of Dauricine significan...
Objective: To investigate the effect of dauricine on the irreversible platelet aggregability of patients with mitral stenosis (MS).Methods: Glycoprotein Ⅳ (GPⅣ ) and thrombospondin (TSP) levels on the membrane surfa...